(n.) An oily, volatile hydrocarbon, obtained by the distillation of caoutchouc or guttaipercha.
Example Sentences:
(1) The location of the internal trans and cis isoprene units in ficaprenol-11 isolated from Ficus elastica was determined by 13C nuclear magnetic resonance.
(2) An enzymatic comparison with a variety of polyprenol substrates indicates that the solubilized kinase prefers long-chain (C90-95) polyprenols with saturated alpha-isoprene units.
(3) Analysis by mass spectrometry and by nuclear magnetic resonance showed that the molecule is formed by condensation of 10 unsaturated isoprene units and 1 saturated isoprene unit.
(4) The chemical structure of synthetic dolichol-19, which was prepared by the addition of a saturated isoprene unit to the polyprenol-18 isolated from Ginkgo biloba, was confirmed to be identical with that of pig liver dolichol-19.
(5) The number of internal trans isoprene residues in this compound was three in comparison with two such residues in long-chain C95-dolichol.
(6) It was demonstrated that C30-C80-polyprenyl phosphates with unsaturated alpha-isoprene unit were as active as natural acceptor (undecaprenyl phosphate) in this enzymic system.
(7) Hb adducts also accumulated linearly after repeated daily administration of 100 mumol [14C]butadiene or 500 mumol [14C]isoprene per kilogram body wt to mice and rats, respectively, for 3 days.
(8) The relative amount of the metabolites present in blood was highest for low concentrations of inhaled isoprene and for shorter exposure durations.
(9) Three side-chains monocarboxylic acids hydroxylated in allylic positions in the isoprene moiety were also characterized.
(10) Catalytic hydrogenolysis has been used as a means of distinguishing between classes of polyprenyl phosphate sugars which contain saturated alpha-isoprene units from those in which this grouping is allylic.
(11) Two isoprenoids with 9 to 10 isoprene chains (polyprenoids), N-(p-methylbenzyl)decaprenylamine and N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine overcame the multidrug resistance almost completely in cultured Chr-24, whereas they only slightly sensitized the parental KB cells to anticancer agents.
(12) This was independent of inhaled isoprene concentration.
(13) The incorporation of radioactive farnesyl pyrophosphate and radioactive geranylnerol and the lack of incorporation of radioactive geranylgeraniol into betulaprenols-6 to -9 demonstrated that they are formed by the cis-additions of isoprene residues to all-trans-farnesyl pyrophosphate.
(14) In brain, spleen, and intestine one-third and in other tissues 10-20% of the total ubiquinone contained 10 isoprene units.
(15) The compound is thus designated MK-8(2H), indicating a menaquinone with eight isoprene units but only seven double bonds in the side chain.
(16) The isoprenoid pattern for dolichol and dolichyl-P, respectively, is modified to longer polyprenols in the two fractions as seen in the percent distribution of the individual isoprenes.
(17) Six differential observations were made: (1) Plastoquinone and ubiquinones, with a side chain of more than two isoprene units, are by far better mediators than their short-chain homologues.
(18) 14CO2 exhalation after the end of the 6-hr exposure was minimal (2%) at the 20 ppm exposure and increased up to 18% at the higher isoprene exposure concentrations.
(19) A biosynthesis of hexahydroprenols by addition of cis-isoprene units to all-trans-geranylgeranyl pyrophosphate, or a dihydro or tetrahydro derivative thereof, is suggested.
(20) A method for the determination of neophytadiene in the total particulate matter of cigarette smoke was developed and applied to test its relationship to isoprene deliveries.
Unsaturated
Definition:
(a.) Capable of absorbing or dissolving to a greater degree; as, an unsaturated solution.
(a.) Capable of taking up, or of uniting with, certain other elements or compounds, without the elimination of any side product; thus, aldehyde, ethylene, and ammonia are unsaturated.
Example Sentences:
(1) An unsaturated fatty acid auxotroph of Escherichia coli was grown with a series of cis-octadecenoate isomers in which the location of the double bond varied from positions 3 to 17.
(2) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(3) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(4) Saturated acyl residues predominated in lysolecithin and unsaturated ones in acids released by hydrolysis of egg lecithin.
(5) The content of unsaturated fatty acids in walleye pollock PRM is 1.4 times greater than in frog PRM.
(6) Taken together with other physical studies on the effect of vitamin E on (unsaturated) phospholipids, these results indicate that vitamin E could influence the physical properties of membrane phospholipids in addition to its known antioxidant role.
(7) Partially purified fatty acid synthetase produced saturated and unsaturated fatty acids with chain lengths of C10 to C18.
(8) The phosphatidylcholine and phosphatidylethanolamine had distinctive fatty acid distributions for position sn-2 of the triacylglycerol had a predominance of unsaturated fatty acids of which 18:1 (69.9%) was the major component.
(9) Alternatively, the data presented herein strongly suggest that diets containing conventional quantities of fat, in which saturated fat is replaced by unsaturated fat and dietary cholesterol reduced, would result in the desired reductions to total and low-density lipoprotein cholesterol concentrations without the adverse effects of increased postprandial glucose and insulin concentrations, increased fasting and postprandial total and very-low-density lipoprotein triglyceride concentrations, and decreased fasting high-density lipoprotein cholesterol concentrations.
(10) While undoubtedly a good understanding of soil microbiology in terms of pedology exists, little is presently known about unsaturated subsoils, and aquifers.
(11) In the intact neutrophil, this enzyme can be activated by increases in cytosolic calcium, protein kinase C, and unsaturated fatty acids such as arachidonic acid, all of which are produced on stimulation by chemotactic peptides like N-formyl-methionyl-leucyl-phenylalanine.
(12) In 8 of 11 patients no changes occurred in excretion of bile acids during the period on unsaturated fat when plasma cholesterol was declining.
(13) linoleic and gamma-linolenic acid also inhibited its secretion, whereas saturated fatty acid and mono-unsaturated fatty acids, such as oleic acid, were without effect.
(14) Patients under caloric restriction showed a reduction in their total triglyceride content, a reduction in their content of unsaturated fatty acyl groups, and a relative increase in phospholipid content.
(15) Protons and divalent cations show synergistic effects on the destabilization of liposomes composed of unsaturated phosphatidylethanolamine and oleic acid (Düzgünes et al., Biochemistry (1985) 24, 3091).
(16) 3H-acetyl CoA is more intensively used in the synthesis of unsaturated fatty acids than 14C-acetyl CoA synthesized from acetate.
(17) Amides containing an epoxy group exhibit a broad spectrum of antimicrobial activity which is further enhanced by unsaturation.
(18) The same enzyme biosynthesises saturated and mono-unsaturated very long chain fatty acids.
(19) In the infected chicks also the transferrin saturation was significantly lower and the unsaturated ironbinding capacity higher, on days 4, 6, and 8 after infection.
(20) Alcohol dehydrogenase purified by CM-cellulose chromatography from the sera of patients with hepatoma had a higher affinity for butanol long chain saturated and unsaturated alcohols than the purified enzyme from healthy controls.