(n.) The act of passing or flowing out; a moving out from any inclosed place; egress; as, the issue of water from a pipe, of blood from a wound, of air from a bellows, of people from a house.
(n.) The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
(n.) That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
(n.) Progeny; a child or children; offspring. In law, sometimes, in a general sense, all persons descended from a common ancestor; all lineal descendants.
(n.) Produce of the earth, or profits of land, tenements, or other property; as, A conveyed to B all his right for a term of years, with all the issues, rents, and profits.
(n.) A discharge of flux, as of blood.
(n.) An artificial ulcer, usually made in the fleshy part of the arm or leg, to produce the secretion and discharge of pus for the relief of some affected part.
(n.) The final outcome or result; upshot; conclusion; event; hence, contest; test; trial.
(n.) A point in debate or controversy on which the parties take affirmative and negative positions; a presentation of alternatives between which to choose or decide.
(n.) In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination. See General issue, under General, and Feigned issue, under Feigned.
(v. i.) To pass or flow out; to run out, as from any inclosed place.
(v. i.) To go out; to rush out; to sally forth; as, troops issued from the town, and attacked the besiegers.
(v. i.) To proceed, as from a source; as, water issues from springs; light issues from the sun.
(v. i.) To proceed, as progeny; to be derived; to be descended; to spring.
(v. i.) To extend; to pass or open; as, the path issues into the highway.
(v. i.) To be produced as an effect or result; to grow or accrue; to arise; to proceed; as, rents and profits issuing from land, tenements, or a capital stock.
(v. i.) To close; to end; to terminate; to turn out; as, we know not how the cause will issue.
(v. i.) In pleading, to come to a point in fact or law, on which the parties join issue.
(v. t.) To send out; to put into circulation; as, to issue notes from a bank.
(v. t.) To deliver for use; as, to issue provisions.
(v. t.) To send out officially; to deliver by authority; as, to issue an order; to issue a writ.
Example Sentences:
(1) You lot have got real issues to talk about and deal with.
(2) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(3) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
(4) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
(5) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
(6) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
(7) Much of the current information concerning this issue is from short-term studies.
(8) It is entirely proper for serving judges to set out the arguments in high-profile cases to help public understanding of the legal issues, as long as it is done in an even-handed way.
(9) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
(10) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
(11) The issue has been raised by an accountant investigating the tax affairs of the duchy – an agricultural, commercial and residential landowner.
(12) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
(13) One is that the issue of whether the World Cup should go ahead in Russia and Qatar still firmly remains on the table.
(14) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
(15) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(16) It can feel as though an official opinion has been issued.
(17) The first part of this survey which dealt with equipment for the anterior segment was published in a previous issue of this journal.
(18) Problem definition, the first step in policy development, includes identifying the issues, discussing and framing the issues, analyzing data and resources, and deciding on a problem definition.
(19) Heathrow, likewise, said Gatwick's new runway would not solve the issue of hub capacity.
(20) The deep green people who have an issue with the language of natural capital are actually making the same jump from value to commodification that they state that they don’t want ... They’ve equated one with the other,” he says.
Produce
Definition:
(v. t.) To bring forward; to lead forth; to offer to view or notice; to exhibit; to show; as, to produce a witness or evidence in court.
(v. t.) To bring forth, as young, or as a natural product or growth; to give birth to; to bear; to generate; to propagate; to yield; to furnish; as, the earth produces grass; trees produce fruit; the clouds produce rain.
(v. t.) To cause to be or to happen; to originate, as an effect or result; to bring about; as, disease produces pain; vice produces misery.
(v. t.) To give being or form to; to manufacture; to make; as, a manufacturer produces excellent wares.
(v. t.) To yield or furnish; to gain; as, money at interest produces an income; capital produces profit.
(v. t.) To draw out; to extend; to lengthen; to prolong; as, to produce a man's life to threescore.
(v. t.) To extend; -- applied to a line, surface, or solid; as, to produce a side of a triangle.
(v. i.) To yield or furnish appropriate offspring, crops, effects, consequences, or results.
(n.) That which is produced, brought forth, or yielded; product; yield; proceeds; result of labor, especially of agricultural labors
(n.) agricultural products.
Example Sentences:
(1) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
(2) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
(3) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(4) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) If ascorbic acid was omitted from the culture medium, the extensive new connective tissue matrix was not produced.
(7) All of the strains examined were motile and hemolytic and produced lipase and liquid gelatin.
(8) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(9) Ethanol and L-ethionine induce acute steatosis without necrosis, whereas azaserine, carbon tetrachloride, and D-galactosamine are known to produce steatosis with varying degrees of hepatic necrosis.
(10) Whereas strain Ga-1 was practically avirulent for mice, strain KL-1 produced death by 21 days in 50% of the mice inoculated.
(11) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(12) Attempts are now being made to use this increased understanding to produce effective killed vaccines that produce immune responses in the lung.
(13) It was also found that lipocortin I and ONO-RS-082, but not neomycin, facilitated the generation of GIF-producing T cells.
(14) The origins of aging of higher forms of life, particularly humans, is presented as the consequence of an evolved balance between 4 specific kinds of dysfunction-producing events and 4 kinds of evolved counteracting effects in long-lived forms.
(15) First, it has diverted grain away from food for fuel, with over a third of US corn now used to produce ethanol and about half of vegetable oils in the EU going towards the production of biodiesel.
(16) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(17) Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation.
(18) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(19) Dilutional studies comparing the mechanism of inhibition of monoamine oxidase produced by Gerovital H3 and by ipronizid demonstrated that Gerovital H3 was a reversible inhibitor of monoamine oxidase.
(20) The AL plus EA produced significantly greater adverse effects than with SFO plus EA.