(1) This enhancer sequence is not strictly cell-type specific since it functions in cell lines of both placental (JEG-3) and pituitary (18-54,SF) origin.
(2) VIP maximally increased the transient expression of CRE alpha CAT and the expression of endogenous hCG-alpha mRNA in JEG-3 cells by 4- and 9-fold, respectively.
(3) This result may be explained by the observation that the JAr cells lacked any detectable glucocorticoid receptor and the receptor levels in cytosol prepared from JEG and BeWo cells were 12% and 2%, respectively, of those measured in HeLa cytosol.
(4) The HLA-6.0 or HLA-E genes may encode the lower molecular mass component on Jeg-3 cells, because these genes express molecules of about 38 kDa and 41 kDa, respectively, when transfected to appropriate host cells.
(5) In order to determine whether RA stimulates the hCG secretion by other trophoblastic cell lines, we evaluated the effect of RA on hCG, hCG-alpha subunit (hCG-alpha), and progesterone secretion in three choriocarcinoma cell lines: JEG-3, JAR, and BeWo.
(6) Reporter genes containing either the intact 1.5 kilobase of 5'-flanking sequence from the HCG alpha gene, or just the 36-bp tandem repeat cAMP response element, when coupled to an enhancerless promoter, both exhibit a vigorous cAMP stimulation of expression but no response to phorbol ester in JEG-3 cells.
(7) We demonstrate the molecular peculiarities of these modified smooth muscle cells using monoclonal antibodies produced against a benign human JEG-cell tumour.
(8) The transcriptional activities of P1 + P2 in their natural tandem orientation were additive in rat keratinocytes and human JEG choriocarcinoma cells.
(9) Using DNase I protection analyses and gel-mobility shift assays, we examined in vitro the domains in the human alpha-gene 5'-flanking sequence that bind nuclear proteins extracted from JEG-3 choriocarcinoma cells.
(10) The effect of JEG-3 choriocarcinoma supernatant on human natural killer cell and lymphokine-activated killer cell activity was investigated.
(11) Similar observations have been made in JeG-3 cells and Chinese hamster ovary cells stably transfected with human apoE cDNA constructs.
(12) In human choriocarcinoma JEG-3 and monkey COS-1 cells, the cytosolic thyroid hormone binding protein is a monomer of the tetrameric pyruvate kinase, subtype M2, which does not bind T3.
(13) In this study the 5'-flanking sequence of the CG beta gene was fused to a sensitive luciferase (LUC) reporter gene, allowing delineation of a CG beta CRE in transient expression assays performed in JEG-3 choriocarcinoma cells.
(14) JEG-3 choriocarcinoma cells demonstrate c-myc transcript levels that are greater than those of nonmalignant trophoblastic tissue at any stage of gestation.
(15) No significant expression of any of these ANG-GH fusion genes over the promoterless pOGH was observed in JEG-3 cells.
(16) Results of these studies suggest that there is some degree of tissue specificity of FN gene expression and reveal that cAMP induction is mediated, in part, by the same element (CRE) in both HT-1080 and JEG-3 cells.
(17) Epidermal growth factor (EGF) binds to JEG-3 cells, a tissue culture line of human choriocarcinoma.
(18) In JEG-3 choriocarcinoma cells the MMTV promoter is transcribed inefficiently, even after transfection of the receptor cDNA and treatment with glucocorticoids or progestins.
(19) A similar increase in Class I antigens is also found in JEG-3 choriocarcinoma cells after treatment with IFN-gamma.
(20) Deletion of the FN promoter from positions -510 to -56 resulted in an ~30-fold decrease in promoter activity when this construction was transfected into HT-1080 cells, and similar results were observed in NIH 3T3 cells; however, less than a 2-fold effect was observed in JEG-3 cells.
Jet
Definition:
(n.) Same as 2d Get.
(n.) A variety of lignite, of a very compact texture and velvet black color, susceptible of a good polish, and often wrought into mourning jewelry, toys, buttons, etc. Formerly called also black amber.
(n.) A shooting forth; a spouting; a spurt; a sudden rush or gush, as of water from a pipe, or of flame from an orifice; also, that which issues in a jet.
(n.) Drift; scope; range, as of an argument.
(n.) The sprue of a type, which is broken from it when the type is cold.
(v. i.) To strut; to walk with a lofty or haughty gait; to be insolent; to obtrude.
(v. i.) To jerk; to jolt; to be shaken.
(v. i.) To shoot forward or out; to project; to jut out.
(v. t.) To spout; to emit in a stream or jet.
Example Sentences:
(1) Pentamidine aerosol was administered with an MA2 jet nebulizer.
(2) A neodymium YAG (Nd:YAG) laser was evaluated in a dog ulcer model used in the same manner as is recommended for bleeding patients (power 55 W, divergence angle 4 degrees, with CO2 gas-jet assistance).
(3) It was found that there was a substantial increase in mortality rates in the area under the jets where there was large noise radiation.
(4) Fleeting though it may have been (he jetted off to New York this morning and is due in Toronto on Saturday), there was a poignant reason for his appearance: he was here to play a tribute set to Frankie Knuckles, the Godfather of house and one of Morales's closest friends, who died suddenly in March.
(5) Kiev said the jets were downed by a missile launched from Russian territory , and that the pilots had parachuted out.
(6) It's been a busy free-agency period for the Eagles, with Michael Vick going to the New York Jets and Mark Sanchez moving in the opposite direction .
(7) In all cases, the maximal velocity of the tricuspid regurgitation jet was measured by continuous wave Doppler ultrasound and the systolic pressure gradient between right ventricle and the right atrium was calculated by the modified Bernoulli equation.
(8) High-frequency two-way jet ventilation was achieved by adding reverse jet pulses inside the trachea through an intratracheal reverse jet system to the expiratory phase of common high-frequency jet ventilation.
(9) He knew how to shmooze Middle East clients and his al-Yamamah deal - under which jets were sold to Saudi Arabia - was the mid-1980s contract which secured his later position as executive chairman at BAE Systems .
(10) Angiographic features felt to indicate valve tearing were present following 17 of 25 procedures and included increased excursion or straightening of leaflets, localized change in leaflet motion (flail leaflet), and the presence of an additional contrast jet through the valve.
(11) The spatial distribution of simulated regurgitant jets imaged by Doppler color flow mapping was evaluated under constant flow and pulsatile flow conditions.
(12) Both intraobserver and interobserver correlations were excellent for mitral regurgitant jet areas (r = 0.97 and r = 0.93, respectively).
(13) Correlation of all Doppler color flow measurements with angiographic grades of mitral regurgitation were comparable, maximal jet area being closest at r = 0.76.
(14) The design of motor cycle helmets has been changing over the years and at the present time there are two basic types in popular use: "full-face" and "jet" helmets.
(15) He says that two dozen Delta Force commandos, Black Hawk helicopters, drones and fighter jets were involved in the rescue, adding “but we weren’t there”.
(16) But 30 minutes before takeoff on our private jet – like a top-end Lexus limo with wings – actress Rosamund Pike has heroically stepped in for the year's hot meal ticket: an El Bulli supper, pitch perfect for a selection of rare champagne, devised by Adrià with Richard Geoffroy, Dom Pérignon's effervescent chef de cave.
(17) The main damage mechanisms are plasma formation and expansion, emission of acoustic transients, and cavitation with jet formation.
(18) The 777 has enjoyed one of the safest records of any jetliner built.” Besides last year’s Asiana crash, the only other serious incident with the 777 came in January 2008 when a British Airways jet landed 305 metres short of the runway at London’s Heathrow airport.
(19) The researcher is completing a PhD on the superyacht scene and says the vessels are unique among prestige assets: unlike private jets they are not a useful mode of transport; unlike art and property, they always depreciate in value.
(20) IDC high-frequency jet ventilation and high-frequency, conventional mechanical ventilation produced nearly identical histologic injuries.