(1) This enhancer sequence is not strictly cell-type specific since it functions in cell lines of both placental (JEG-3) and pituitary (18-54,SF) origin.
(2) VIP maximally increased the transient expression of CRE alpha CAT and the expression of endogenous hCG-alpha mRNA in JEG-3 cells by 4- and 9-fold, respectively.
(3) This result may be explained by the observation that the JAr cells lacked any detectable glucocorticoid receptor and the receptor levels in cytosol prepared from JEG and BeWo cells were 12% and 2%, respectively, of those measured in HeLa cytosol.
(4) The HLA-6.0 or HLA-E genes may encode the lower molecular mass component on Jeg-3 cells, because these genes express molecules of about 38 kDa and 41 kDa, respectively, when transfected to appropriate host cells.
(5) In order to determine whether RA stimulates the hCG secretion by other trophoblastic cell lines, we evaluated the effect of RA on hCG, hCG-alpha subunit (hCG-alpha), and progesterone secretion in three choriocarcinoma cell lines: JEG-3, JAR, and BeWo.
(6) Reporter genes containing either the intact 1.5 kilobase of 5'-flanking sequence from the HCG alpha gene, or just the 36-bp tandem repeat cAMP response element, when coupled to an enhancerless promoter, both exhibit a vigorous cAMP stimulation of expression but no response to phorbol ester in JEG-3 cells.
(7) We demonstrate the molecular peculiarities of these modified smooth muscle cells using monoclonal antibodies produced against a benign human JEG-cell tumour.
(8) The transcriptional activities of P1 + P2 in their natural tandem orientation were additive in rat keratinocytes and human JEG choriocarcinoma cells.
(9) Using DNase I protection analyses and gel-mobility shift assays, we examined in vitro the domains in the human alpha-gene 5'-flanking sequence that bind nuclear proteins extracted from JEG-3 choriocarcinoma cells.
(10) The effect of JEG-3 choriocarcinoma supernatant on human natural killer cell and lymphokine-activated killer cell activity was investigated.
(11) Similar observations have been made in JeG-3 cells and Chinese hamster ovary cells stably transfected with human apoE cDNA constructs.
(12) In human choriocarcinoma JEG-3 and monkey COS-1 cells, the cytosolic thyroid hormone binding protein is a monomer of the tetrameric pyruvate kinase, subtype M2, which does not bind T3.
(13) In this study the 5'-flanking sequence of the CG beta gene was fused to a sensitive luciferase (LUC) reporter gene, allowing delineation of a CG beta CRE in transient expression assays performed in JEG-3 choriocarcinoma cells.
(14) JEG-3 choriocarcinoma cells demonstrate c-myc transcript levels that are greater than those of nonmalignant trophoblastic tissue at any stage of gestation.
(15) No significant expression of any of these ANG-GH fusion genes over the promoterless pOGH was observed in JEG-3 cells.
(16) Results of these studies suggest that there is some degree of tissue specificity of FN gene expression and reveal that cAMP induction is mediated, in part, by the same element (CRE) in both HT-1080 and JEG-3 cells.
(17) Epidermal growth factor (EGF) binds to JEG-3 cells, a tissue culture line of human choriocarcinoma.
(18) In JEG-3 choriocarcinoma cells the MMTV promoter is transcribed inefficiently, even after transfection of the receptor cDNA and treatment with glucocorticoids or progestins.
(19) A similar increase in Class I antigens is also found in JEG-3 choriocarcinoma cells after treatment with IFN-gamma.
(20) Deletion of the FN promoter from positions -510 to -56 resulted in an ~30-fold decrease in promoter activity when this construction was transfected into HT-1080 cells, and similar results were observed in NIH 3T3 cells; however, less than a 2-fold effect was observed in JEG-3 cells.
Jog
Definition:
(v. t.) To push or shake with the elbow or hand; to jostle; esp., to push or touch, in order to give notice, to excite one's attention, or to warn.
(v. t.) To suggest to; to notify; to remind; to call the attention of; as, to jog the memory.
(v. t.) To cause to jog; to drive at a jog, as a horse. See Jog, v. i.
(v. i.) To move by jogs or small shocks, like those of a slow trot; to move slowly, leisurely, or monotonously; -- usually with on, sometimes with over.
(n.) A slight shake; a shake or push intended to give notice or awaken attention; a push; a jolt.
(n.) A rub; a slight stop; an obstruction; hence, an irregularity in motion of from; a hitch; a break in the direction of a line or the surface of a plane.
Example Sentences:
(1) Training must be based on physical exercises in endurance (jogging, bicycle) at the rate of 3 weekly sessions to reach a good level of intensity corresponding at least to an energy consumption of 2,000 calories per week.
(2) To determine whether recreational levels of training (jogging) will provoke short luteal phase menstrual cycles, a prospective study was conducted.
(3) On separate occasions, each subject walked (4.8 kph) or jogged (9.6 kph) for 25 min.
(4) Participation in vigorous sports activities, such as jogging, swimming, tennis, etc., helps to protect against the development of hypertension, even when other predisposing factors are present.
(5) The solution is for Hathaway to spend a year in sarky Manchester, where her attempts to go jogging will be thwarted by 324 days of rain, and if she so much as thinks about telling a Mancunian barmaid that she has poured those lagers fantastically well, she will swiftly learn an aloofness not taught in any American drama school.
(6) Patients' confidence in their ability to jog various distances was measured with a jog self-efficacy (SE) scale before a group exercise program was begun.
(7) In Portland, their routine starts with Farah and Rupp running 12 miles on grass before they jog to a running track that seems to have been dropped from 30,000 feet into the woods.
(8) In the present study, insulin action was determined using the euglycemic clamp technique in six untrained nonobese subjects before, during, and after long-term mild regular jogging.
(9) In the training group, patients performed 2 km walk-jog exercise everyday for 1 month, keeping their heart rate (HR) at 90-100% of that in the anaerobic threshold.
(10) 8.08pm BST 6 min: Baines goes on a wee jog down the left, and guides a cross-cum-pass into the area for Rooney, arriving late level with the left-hand post, ten yards out.
(11) They’d say: ‘Today he’s jogging but he doesn’t look quite right’.
(12) The levels of the thyrotropic and thyroid hormones were studied in the serum of 115 persons going in for jogging and in 271 persons not going in for jogging, using a radioimmunoassay.
(13) Under the name of "brain jogging", an economical programme is introduced for mental training, aimed at maintaining and improving basic central information processing capacities.
(14) The aerobic regimen consisted of walking, jogging, stationary bicycling, or any combination of these activities for 30 minutes, four times a week, at 65-80% maximal heart rate.
(15) These findings indicate that water walking could serve as an effective exercise mode, for example, for cardiorespiratory fitness for individuals who are unable to perform such weight-bearing activities as jogging, fast walking, cycling, and dancing.
(16) The change in the aggregation response was significant for t alpha at month 1 and for delta tmax at month 2 after starting the jogging.
(17) Endurance jogging reduced the sympathetic response to moderate exercise.
(18) Physiologic levels were maintained during the final 8 weeks and showed no differences between the CST and jogging groups.
(19) The training program consisted of three 45-min walking and jogging exercise sessions per week at an intensity of approximately 60-85% of the heart rate at peak VO2.
(20) Five healthy, mature, previously trained Standardbred horses were given no exercise (left in a stall) for 4 months, then jogged (slow exercise) for 3 weeks, and placed in a 6-week training period.