(n.) One of a large class of organic substances resembling the aldehydes, obtained by the distillation of certain salts of organic acids and consisting of carbonyl (CO) united with two hydrocarbon radicals. In general the ketones are colorless volatile liquids having a pungent ethereal odor.
Example Sentences:
(1) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(2) Urinalysis revealed a low pH, increased ketones and bilirubin excretion, dark yellowish change in color, the appearance of "leaflet-shaped" crystals and increased red blood cells and epithelial cells in the urinary sediment, increased water intake, decreased specific gravity and decreased sodium, potassium and chloride in the urine.
(3) The infusion of sodium acetoacetate resulted in a 10- to 15-fold increase in circulating concentrations of ketone bodies, which were similar in magnitude in normal subjects and diabetic patients.
(4) Results of repeated visual readings spread over three different color blocks for certain concentrations of glucose, ketone, and protein, whereas repeated instrumental readings were never spread greater than two color blocks.
(5) The plasma concentrations of alanine and proline as well as other amino acids increased as the blood ketone body ratio decreased.
(6) Trifluoromethyl ketone dipeptide analogues are good inhibitors of angiotensin converting enzyme.
(7) As a conclusion sec-butanol, probably through its metabolite methyl-ethyl-ketone, is the most potent inducer of microsomal cytochrome P-450 in liver and kidney while iso-butanol does not alter total cytochrome P-450.
(8) A model of increased microvascular permeability pulmonary edema was developed in chronically instrumented unanesthetized sheep using perilla ketone (PK).
(9) Administration of different brain fuels--glucose, mannose, fructose, or the ketone beta-hydroxybutyrate--reduced hippocampal damage induced by coadministration of GCs and either of 2 different neurotoxins (kainic acid and 3-acetylpyridine).
(10) We report the effects of n-alkanols (n-butanol to n-octanol), methyl carboxylic esters (methyl propionate to methyl octanoate) and n-alkyl ketones (2-pentanone to 2-nonanone) on a fast reflex escape response to a mechanical stimulus in Gammarus.
(11) Examination of other potential inhibitors revealed a rank order of potency against calpain to be: peptidyl sulphonium methyl ketones > fluoromethyl ketones, diazomethyl ketones >> acyloxymethyl ketones, an order which differs sharply from that found for cathespin B.
(12) Epigalanthamine, a diastereomer of GAL, was 130-times less potent in vitro in its effect on acetylcholinesterase (AChE) in erythrocytes than the parent compound, and it did not differ significantly from the ketone galanthaminone.
(13) Also, a significant correlation was found between the levels of urine glucose and ketones and the level of acyl carnitine.
(14) This is in contrast to fasting adult dogs, which maintain glucohomeostasis and show only slightly decreased insulin levels, normal glucagon levels and a moderate increase of plasma ketone bodies.
(15) The following processes are discussed in this article: enzyme-catalysed hydrolyses of carboxylic acid esters and amides, phosphate esters, nitriles and epoxides; esterification and inter-esterification reactions catalysed by enzymes; reduction of ketones to secondary alcohols using whole-cell systems or isolated dehydrogenases; oxidation of alicyclic and aromatic substrates using mono-oxygenases and dioxygenases in bacteria and fungi including enzyme-catalysed Baeyer-Villiger oxidations; aldol reactions, formation of optically active cyanohydrins and enzyme-catalysed acyloin type reactions.
(16) The paint base consisted primarily of toluene and methyl ethyl ketone.
(17) Ketonic bodies participate in the power supply of cortex functions of satisfied one-day pigs but their contribution to the nerve tissue power of fasting one-and five-day pigs is insignificant.
(18) Mechanism-based inhibition of myocardial cytosolic calcium-independent phospholipase A2 by Compound 1 was established by demonstrating: 1) time-dependent irreversible inactivation; 2) covalent binding of [3H]Compound 1 to the purified phospholipase A2; 3) ablation of covalent binding of [3H]Compound 1 after chemical inactivation of phospholipase A2 enzymic activity; 4) identical inhibition of myocardial phospholipase A2 by Compound 1 in the absence or presence of nucleophilic scavengers; 5) Compound 1 is a substrate for myocardial calcium-independent phospholipase A2 resulting in the generation of the electrophilic alpha-bromomethyl ketone; 6) phospholipase A2 inhibition requires the in situ generation of the reactive electrophile (i.e.
(19) Inhibition by phenylmethanesulfonyl fluoride and N alpha-p-tosyl-L-lysine chloromethyl ketone indicates the presence of serine and histidine residues in the active center, respectively.
(20) In addition, adrenal S-adenosylmethionine (SAM) and blood ketone bodies were determined Sections of adrenals were evaluated by electron microscopy for histopathological changes.
Organic
Definition:
(a.) Of or pertaining to an organ or its functions, or to objects composed of organs; consisting of organs, or containing them; as, the organic structure of animals and plants; exhibiting characters peculiar to living organisms; as, organic bodies, organic life, organic remains. Cf. Inorganic.
(a.) Produced by the organs; as, organic pleasure.
(a.) Instrumental; acting as instruments of nature or of art to a certain destined function or end.
(a.) Forming a whole composed of organs. Hence: Of or pertaining to a system of organs; inherent in, or resulting from, a certain organization; as, an organic government; his love of truth was not inculcated, but organic.
(a.) Pertaining to, or denoting, any one of the large series of substances which, in nature or origin, are connected with vital processes, and include many substances of artificial production which may or may not occur in animals or plants; -- contrasted with inorganic.
Example Sentences:
(1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(2) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
(3) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(4) After 3 and 6 months, blood collected by cardiocentesis using ether anesthesia and then sacrificed to remove CNS and internal organs.
(5) Addition of phospholipase A2 from Vipera russelli venom led to a significant increase in the activity of guanylate cyclase in various rat organs.
(6) For the first time it was organized on the basis of population.
(7) Acceptance of less than ideal donors is ill-advised even though rejection of such donors conflicts with the current shortage of organs.
(8) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
(9) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(10) Recovery of CV-3988 from plasma averaged 81.7% for the column procedure and 40% for the organic extraction.
(11) One of the main users is coastal planning organizations and conservation organizations that are working on coral reefs.
(12) Infection with opportunistic organisms, either singly or in combination, is known to occur in immunocompromised patients.
(13) The causative organisms included viruses, fungi, and bacteria of both high and low pathogenicity.
(14) A chronic cannulation procedure is described which allows for sampling vomeronasal organ (VNO) contents repeatedly in freely moving conscious subjects.
(15) Neither Brucella organisms, nor increased numbers of neutrophils could be found in semen samples collected from the experimental animals.
(16) The lineage and clonality of Hodgkin's disease (HD) were investigated by analyzing the organization of the immunoglobulin and T-cell receptor beta-chain (T beta) gene loci in 18 cases of HD, and for comparison, in a panel of 103 cases of B- and T-cell non-Hodgkin's lymphomas (NHLs) and lymphoid leukemias (LLs).
(17) A review is made from literature and an inventory of psychological and organic factors implicated in this pathology.
(18) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(19) Data is available to support the early influences of enamel organ epithelium upon a responding mesenchyme in the determination of dental morphogenetic fields (Dryburg, 1967; Miller, 1969).
(20) The four deaths were not related to the injuries of parenchymatous organs.