(1) Since the protective protein possesses extensive sequence homology with carboxypeptidase Y (carb Y) and the KEX 1 gene product from yeast, we have used the artificial substrate N-CBZ-Phe-Leu to detect and characterize the peptidase activity of the lysosomal carboxypeptidase (carb L).
(2) To study the molecular mechanisms involved in polyprotein processing, we have transfected the yeast KEX-2 gene into mouse NIH 3T3 fibroblasts and established a new cell line (called 2N-DK) where the KEX-2 endoprotease is permanently expressed.
(3) • Doubles from £117 room-only, Laugavegur 66-68, +354 553 9366, aldahotel.is Kex Hostel Facebook Twitter Pinterest Not only is Kex one of the smartest hostels you’ll come across, it’s also one of the coolest places to hang out in Reykjavik – whether that’s listening to bands playing in the bar (or on the terrace), eating in the superb bar or relaxing in the lounge.
(4) The first-order rates are compared with that of a fourth variant Phe82----Gly which has been measured previously (E0 = 220 mV, kex = 0.7 s-1).
(5) While the mammalian endoproteases responsible for these cleavages are yet to be identified, this function has been unequivocally assigned in yeast to the product of the KEX-2 gene.
(6) The evidence for this cellular location is supported by measurement of intracellular and extracellular KEX-2 enzyme activity.
(7) The apparent pseudo-first-order exchange rate, kex, of the backbone amide protons and the correspondent activation enthalpies, delta H not equal to, were determined.
(8) For all other backbone amide protons in BPTI, the exchange was found to be uncorrelated and by an EX2 mechanism under all conditions of p2H and temperature where quantitative measurements could be obtained with the methods used, i.e., for kex approximately less than 5 min-1.
(9) For three variants of yeast iso-1-cytochrome c the rate constants measured by saturation transfer are wild-type (Asn52, E0 = 270 mV, kex = 0.3 s-1), Asn52----Ala (E0 = 240 mV, kex = 0.6 s-1), Asn52----Ile (E0 = 220 mV, kex = 1.0 s-1).
(10) It was found that the KEX-2 protease was unable to cleave the prepro-Lys-Arg-Pro-IL6 sequence, but that unspecific cleavage of the precursor protein had occurred.
(11) Thus, the kex phenotype does not require an alteration of the killer plasmid.--Kex1 and kex2 strains each contain near-normal levels of the 1.4 x 10(6) molecular weight double-stranded RNA, whose presence is correlated with the presence of the killer genome.
(12) The experimental study showed that KEX-I can inactivate directly the virus of Coxsackie B3, protect the heart cells in mice, prevent attack by Coxsackie B3, promote the growth of internal interferon and increase the NK cell's function to regulate immunity in experimental mice.
(13) When P2 organelles were separated in sucrose density gradients Rho1p comigrated with the Kex-2 activity, a late Golgi marker.
(14) Insulin affected both rate constants, reducing k(in) by 2.8-fold and increasing kex by 3.3-fold.
(15) The rate constants of efficient exchange interaction (kex) of spin-labelled lysozyme and the triplet probes perylene, eosine and anthracene butanoic acid with the haemoproteins were measured in microsomes and in solution by electron paramagnetic resonance and by the registration of delayed annihilation fluorescence.
(16) The look of Kex is, in part, down to Hálfdan Lárus Pedersen, a film production designer.
(17) At pH 6.0, first order rate constants for amino acid exit (kex) under steady state conditions for L-leucine, L-alanine, and L-serine were 1.1-1.3, 0.084, and 0.053 min-1, respectively.
(18) Most significantly, cleavage of the precursor to SRIF-28 was independent of the Kex 2 endoprotease since processing occurred efficiently in a kex 2 mutant strain.
(19) The clinical study was carried out with KEX-I according to a random, paired and cross-over design.
(20) Of particular clinical relevance is the [Cai] response to cardioplegia containing 16 mM [Kex]: neither group demonstrated the expected [Cai] increase in response to potassium depolarization.
Rex
Definition:
(n.) A king.
Example Sentences:
(1) Bio-Rex 70, a carboxylic acid cation exchanger, is studied as a biological ion-exchanger resin model for cellular cytoplasm.
(2) Photograph: Rex Features 'Voga' Vogueing + yoga, apparently.
(3) Photograph: Rex Features If Brookstein had confined his anger to legitimate provocations, it would be easier to sympathise, for he seems to have suffered more than enough of them on The X Factor.
(4) Using an extracellular microelectrode recording technique, the effects of intravenously administered morphine sulfate upon the single-unit activities of cells in Rexed lamina VII of the lumbar spinal cord were studied in cats following decerebration and spinal cord transection at L1.
(5) Photograph: Rex If they are still unhappy they can go to the free Financial Ombudsman Service (FOS), which resolves disputes between consumers and financial firms, although the PAC raised concerns about the service’s backlog of cases.
(6) The lateral basal region (LBR) of the spinal cord gray matter (Rexed's laminae IV-VII) by physiologic and anatomic criteria is the major terminal zone for the corticospinal (CS) tract in the cat.
(7) Phosphorylation of Rex occurred in all HTLV-I-infected cell lines examined in vivo, primarily at serine residues and to a very small extent at threonine residues.
(8) Mutations bas, rex and sesD delay recovery from the prolonged depolarization afterpotential.
(9) In the upper cervical cord of chick embryos at stage 36 when all spinal neurons finished cell migration and the cytoarchitecture similar to that of the cat spinal cord (Rexed, 1952) could be recognized (cf.
(10) For the second show in the Guardian’s 10-week radio series on NTS, Alexis talked to the Guide’s Kate Hutchinson about glam’s early innovators, forgotten outliers and its modern descendants: T Rex to David Bowie and Iron Virgin to Perfume Genius.
(11) Chymotryptic digestion of phosphorylated Rex yielded two phosphopeptides.
(12) Rex also bound in vitro to the human immunodeficiency virus type 1 (HIV-1) Rev-responsive element (RRE), while purified HIV-1 Rev protein did not bind to the RXRE.
(13) The state department issued a stinging rebuke of the behaviour of the Saudis and their Egyptian, Emirati and Bahraini allies, with the secretary of state, Rex Tillerson, warning them to make their demands on Qatar “ reasonable and actionable ”.
(14) The vibrissae of rex are curved or bent and may break off; those of waved are a mixture of straight, curved, and bent hairs.
(15) Therefore, binding of RevBL to the RRE had neither positive nor negative effects on the mRNA, since this mRNA could be efficiently utilized in the presence of a functional Rex-RXRE interaction.
(16) The results of the present study are, to the authors' knowledge, the first demonstration of the suppressive effect of morphine on the spinal nociceptive neurons in Rexed lamina V as they respond to graded noxious thermal stimuli.
(17) On the basis of these in vitro data the observed defect in the Devon Rex cats can be fully explained.
(18) Photograph: REX Shutterstock Nicky Morgan S ecretary of state for education and minister for women and equalities Morgan dramatically increased her majority at the election and she will keep both of her ministerial briefs, where she won plaudits especially for her rethink on equal marriage, which she had previously opposed.
(19) Photograph: Rex Feeding into this narrative, an email from Sarah Vine, Gove’s wife, was accidentally sent to a member of the public, leaking details of her reservations about Johnson’s popularity with members and media bosses.
(20) One of these mutants is able to suppress the function of the wild-type HTLV-I Rex protein in trans on the homologous rex response element sequence.