(1) Since the protective protein possesses extensive sequence homology with carboxypeptidase Y (carb Y) and the KEX 1 gene product from yeast, we have used the artificial substrate N-CBZ-Phe-Leu to detect and characterize the peptidase activity of the lysosomal carboxypeptidase (carb L).
(2) To study the molecular mechanisms involved in polyprotein processing, we have transfected the yeast KEX-2 gene into mouse NIH 3T3 fibroblasts and established a new cell line (called 2N-DK) where the KEX-2 endoprotease is permanently expressed.
(3) • Doubles from £117 room-only, Laugavegur 66-68, +354 553 9366, aldahotel.is Kex Hostel Facebook Twitter Pinterest Not only is Kex one of the smartest hostels you’ll come across, it’s also one of the coolest places to hang out in Reykjavik – whether that’s listening to bands playing in the bar (or on the terrace), eating in the superb bar or relaxing in the lounge.
(4) The first-order rates are compared with that of a fourth variant Phe82----Gly which has been measured previously (E0 = 220 mV, kex = 0.7 s-1).
(5) While the mammalian endoproteases responsible for these cleavages are yet to be identified, this function has been unequivocally assigned in yeast to the product of the KEX-2 gene.
(6) The evidence for this cellular location is supported by measurement of intracellular and extracellular KEX-2 enzyme activity.
(7) The apparent pseudo-first-order exchange rate, kex, of the backbone amide protons and the correspondent activation enthalpies, delta H not equal to, were determined.
(8) For all other backbone amide protons in BPTI, the exchange was found to be uncorrelated and by an EX2 mechanism under all conditions of p2H and temperature where quantitative measurements could be obtained with the methods used, i.e., for kex approximately less than 5 min-1.
(9) For three variants of yeast iso-1-cytochrome c the rate constants measured by saturation transfer are wild-type (Asn52, E0 = 270 mV, kex = 0.3 s-1), Asn52----Ala (E0 = 240 mV, kex = 0.6 s-1), Asn52----Ile (E0 = 220 mV, kex = 1.0 s-1).
(10) It was found that the KEX-2 protease was unable to cleave the prepro-Lys-Arg-Pro-IL6 sequence, but that unspecific cleavage of the precursor protein had occurred.
(11) Thus, the kex phenotype does not require an alteration of the killer plasmid.--Kex1 and kex2 strains each contain near-normal levels of the 1.4 x 10(6) molecular weight double-stranded RNA, whose presence is correlated with the presence of the killer genome.
(12) The experimental study showed that KEX-I can inactivate directly the virus of Coxsackie B3, protect the heart cells in mice, prevent attack by Coxsackie B3, promote the growth of internal interferon and increase the NK cell's function to regulate immunity in experimental mice.
(13) When P2 organelles were separated in sucrose density gradients Rho1p comigrated with the Kex-2 activity, a late Golgi marker.
(14) Insulin affected both rate constants, reducing k(in) by 2.8-fold and increasing kex by 3.3-fold.
(15) The rate constants of efficient exchange interaction (kex) of spin-labelled lysozyme and the triplet probes perylene, eosine and anthracene butanoic acid with the haemoproteins were measured in microsomes and in solution by electron paramagnetic resonance and by the registration of delayed annihilation fluorescence.
(16) The look of Kex is, in part, down to Hálfdan Lárus Pedersen, a film production designer.
(17) At pH 6.0, first order rate constants for amino acid exit (kex) under steady state conditions for L-leucine, L-alanine, and L-serine were 1.1-1.3, 0.084, and 0.053 min-1, respectively.
(18) Most significantly, cleavage of the precursor to SRIF-28 was independent of the Kex 2 endoprotease since processing occurred efficiently in a kex 2 mutant strain.
(19) The clinical study was carried out with KEX-I according to a random, paired and cross-over design.
(20) Of particular clinical relevance is the [Cai] response to cardioplegia containing 16 mM [Kex]: neither group demonstrated the expected [Cai] increase in response to potassium depolarization.
Weed
Definition:
(n.) A garment; clothing; especially, an upper or outer garment.
(n.) An article of dress worn in token of grief; a mourning garment or badge; as, he wore a weed on his hat; especially, in the plural, mourning garb, as of a woman; as, a widow's weeds.
(n.) A sudden illness or relapse, often attended with fever, which attacks women in childbed.
(n.) Underbrush; low shrubs.
(n.) Any plant growing in cultivated ground to the injury of the crop or desired vegetation, or to the disfigurement of the place; an unsightly, useless, or injurious plant.
(n.) Fig.: Something unprofitable or troublesome; anything useless.
(n.) An animal unfit to breed from.
(n.) Tobacco, or a cigar.
(v. t.) To free from noxious plants; to clear of weeds; as, to weed corn or onions; to weed a garden.
(v. t.) To take away, as noxious plants; to remove, as something hurtful; to extirpate.
(v. t.) To free from anything hurtful or offensive.
(v. t.) To reject as unfit for breeding purposes.
Example Sentences:
(1) Careless Herbicidal aerial spray of a field for weed control and defoliation of cotton before machine picking, resulted in the contamination of an adjoining reservoir, killing large volume of fish.
(2) In lieu of crop rotation and biodiversity (the non-toxic way to control weeds), the MSU extension service promotes what the article calls a "diversified herbicide program".
(3) The condition has occurred for many years and has been thought to have been associated with ingestion of Crofton weed (Eupatorium adenophorum).
(4) There is, of course, a place for regulatory vigilance, for forcing entire institutions to clean up after themselves by paying hefty fines, and weeding out bad practices.
(5) In allergologic out-patient departments of Dubrovnik, Split, Sibenik, Zadar, Pula and Rijeka, 300 patients with pollinosis have been tested by the application of the prick method of group allergens of grass, tree and weed pollen, particularly of Parietariae (pellitory) pollen.
(6) The coalition claims that authorities were forcing teachers, businessmen and students to weed the fields or pick cotton or face fines of up to 1 million soum (about £210) for university students.
(7) Bob McCulloch, the St Louis County prosecutor who oversaw the state grand jury inquiry that looked into Brown’s death, insisted that discrimination by law enforcement was a rarity but said authorities must “weed it out”.
(8) Unions blame 70% fall in employment tribunal cases on fees Read more “The government originally said making people pay would weed out vexatious claims.
(9) He also promised Thatcher a new crackdown on immigrant male fiances, saying that he was thinking of "a kind of steeplechase designed to weed out south Asians in particular".
(10) The substances studied generally proved very active against the weeds tested and showed marked specificity of action towards Setaria and Echinochloa.
(11) We haven’t ascertained how much of the forests it has taken over, but a significant portion may in reality be unpalatable weeds and effectively unusable from an elephant’s perspective.
(12) In a statement on Wednesday , he said that he will criticise the Met for "the routine gathering and retention of information that was collateral, not linked to an operation or the prevention of crime and it should have been disposed of as part of a weeding process."
(13) But the matriarch of women who toke is Nancy Botwin ( Mary-Louise Parker ) in the long-running TV series Weeds .
(14) One of their number, James Howard Kunstler, blasted the High Line as "decadent" , "a weed-filled 1.5 mile-long stretch of abandoned elevated railroad", where "mistakes are artfully multiplied and layered", such as "the notion that buildings don't have to relate to the street-and-block grid ... instead of repairing the discontinuities of recent decades, we just celebrate them and make them worse".
(15) We have the know-how to track organisations that achieve the best results for patients, and weed out those that don't come up to scratch."
(16) After weeding, planting or harvesting, people attempt to make money.
(17) Animal Practice is a Universal Television production based on an irreverent New York veterinarian, played by Justin Kirk of Weeds and Angels in America.
(18) Some physicochemical properties of the mitochondrial DNAs (mtDNA) from plants of flax, broad bean and mung bean, and from tissue culture cells of jimson weed, soybean, petunia and tobacco were determined.
(19) Weed and water samples collected from river water abstraction points, reservoirs, tap water supplies, and animal water troughs fed from this supply all contained low levels of iodine-125.
(20) There has been a troubling several decade-long pattern of denial on the part of the seed patent holders over the likelihood of resistance emerging - for example Monsanto authors of a 1997 paper asserted weed resistance would never happen.