(n.) The tonic or first tone of the scale in which a piece or passage is written; the fundamental tone of the chord, to which all the modulations of the piece are referred; -- called also key tone.
(n.) The fundamental fact or idea; that which gives the key; as, the keynote of a policy or a sermon.
Example Sentences:
(1) During his MIPCOM keynote, he also took a pop at Rising Star, a much-hyped format that saw a wall lowered to reveal contestants to the studio audience if enough people voted at home.
(2) In a keynote speech at the Lyndon B Johnson presidential library in Austin, Texas, America's first black president said he and others of his generation had greatly benefited from the era of civil rights ushered in by the legislation that was passed by Johnson in 1964.
(3) May was preparing to visit the Gulf Co-operation Council early this week, and Johnson himself is scheduled to make the keynote address at a high-profile security conference in Bahrain this weekend.
(4) In his keynote speech in Manchester , Ed Miliband taunted the prime minister for lying awake at night worrying not about the future of the United Kingdom but rather the United Kingdom Independence party.
(5) Mauricio Funes, the president of El Salvador and a keynote speaker at Thursday's World Bank event, laid out the key components of these integrated approaches, looking to a reform initiative already underway in the small country, that is yielding slow but steady results.
(6) Cameron is to deliver a keynote speech on Britain’s role in the EU on Thursday in Davos.
(7) His aides said the keynote speech was not a call for revolution across the region, but to recognise that the west cannot stand aside from struggles such as the one in Syria.
(8) CPAC performance: Cruz was the keynote speaker at CPAC 2013, a prime spot in the lineup, and he came out and gave a special introduction to Sarah Palin.
(9) Read more Following her keynote speech, Clinton answered questions from tech columnist Kara Swisher, of Recode, touching on topics such as Edward Snowden, net neutrality and, of course, her prospective presidential run.
(10) In the buildup to the keynote address, the convention listened to a series of tributes from members of his Mormon church, former business colleagues and fellow politicians.
(11) Salmond himself will make several more keynote speeches as he eases himself back into the saddle.
(12) Abbott on Thursday night used a keynote address to the World Economic Forum to outline his objectives for a G20 meeting in Brisbane, lay down some broad philosophical markers for his new government on the subject of economic policy, and deliver a clip around the ears for Labor.
(13) Only one of his sculptures is here, while several more are in The Encyclopaedic Palace, the keynote show of the current Venice Biennale, which opened last week.
(14) Its keynote speaker will be Alex Salmond , the first minister and Scottish National party leader whose landslide victory two years ago in the Scottish parliament elections delivered the referendum that had been, until now, an 80-year-old dream for his party.
(15) Nurses are angry that Lansley refused to deliver a keynote speech to the conference, opting instead to meet a group of around 60 nurses in Liverpool as part of a listening exercise on the controversial reforms.
(16) The grim figures are being publicised by the unions today in advance of the opening of the keynote International Trade Fair in the northern city of Thessaloniki and the arrival on Friday of leading monitors from Greece's "troika" of creditors, the European Union, European Central Bank and International Monetary Fund.
(17) I think a lot of voters who vote for Trump take Trump seriously but not literally, so when they hear things like the Muslim comment or the wall comment their question is not, ‘Are you going to build a wall like the Great Wall of China?’ or, you know, ‘How exactly are you going to enforce these tests?’ What they hear is we’re going to have a saner, more sensible immigration policy.” During his speech at the Republican national convention, which Thiel attended as a keynote speaker , Trump was interrupted with chants of “Build a wall.” Thiel also defended Trump’s failure to release his tax returns, saying that we know enough about the candidate’s business dealings.
(18) Clinton made the comments in a question and answer session following a keynote address to technology executives at the “Lead On” conference in Santa Clara, organised by Watermark .
(19) On Saturday he was the keynote speaker at the Manama Dialogue, a prestigious strategic conference held annually in the Bahraini capital.
(20) After talks in Riyadh, Obama will deliver a keynote speech in Cairo .
Tonic
Definition:
(a.) Of or relating to tones or sounds; specifically (Phon.), applied to, or distingshing, a speech sound made with tone unmixed and undimmed by obstruction, such sounds, namely, the vowels and diphthongs, being so called by Dr. James Rush (1833) " from their forming the purest and most plastic material of intonation."
(a.) Of or pertaining to tension; increasing tension; hence, increasing strength; as, tonic power.
(a.) Increasing strength, or the tone of the animal system; obviating the effects of debility, and restoring healthy functions.
(n.) A tonic element or letter; a vowel or a diphthong.
(n.) The key tone, or first tone of any scale.
(n.) A medicine that increases the strength, and gives vigor of action to the system.
Example Sentences:
(1) It is suggested that diabetes causes selective changes in the functioning of Gi in adipocyte membranes which removes the tonic GTP-dependent inhibitory function of this G-protein.
(2) Other Christmas favourites, including stollen, organic mince pies and Schweppes tonic will also be included among 100 seasonal products on the list of 1,000 items which shoppers can choose from over the next few months.
(3) In intact cell preparations, diamide produced a slow tonic contraction, consistent with myofibril activation.
(4) However, tetanic stimulation gave the same results as in untreated preparations when the tonicity was increased.
(5) Stimulus-response characteristics suggested that this system was well suited for a role in tonic inhibition of sympathetic activity.
(6) The amplitude was 15-70% as large as the tonic component of the K-contracture induced by 40 mM K. Theophylline (10 mM), 0.1 mM papaverine and 1 microM isoprenaline nearly abolished, and 1 mM cAMP partly depressed the tonic contraction of K-contracture, whereas the tonic contraction induced by the test solution was unaffected.
(7) While tonic pupil and reduced sweating can be attributed to the affection of postganglionic cholinergic parasympathetic and sympathetic fibres projecting to the iris and sweat glands, respectively, the pathogenesis of diminished or lost tendon jerks remains obscure.
(8) Some organization schemes concerning locomotor and scratching rhythmicity generators are considered, such as: two half-centres with reciprocal inhibitory connections and tonic excitatory influences on these half-centres: two half-centres with inhibitory-excitatory connections and tonic excitatory influences on one half-centre; ring structures consisting of more than two functional groups of neurons with excitatory and inhibitory connections between them.
(9) Overall, carbamazepine and phenytoin are recommended drugs of first choice for single-drug therapy of adults with partial or generalized tonic-clonic seizures or with both.
(10) It was previously believed that the period of the circadian clock was primarily responsive to externally imposed tonic or phasic events.
(11) For now, he leans on the bar – a big man, XL T-shirt – and, in a soft Irish accent, orders himself a small gin and tonic and a bottle of mineral water.
(12) Relying on traditional medicine, all 20 women reported eating brown seaweed soup for 20 days after childbirth, and 5 said that they took tonic herbs during the puerperium.
(13) Amplitudes of the tonic response evoked by 39 mM-K+ in intact muscle tissues and the contraction induced by 0.3 microM-Ca2+ in skinned muscle were much the same.
(14) Tonic sympathetic neural control of heart rate was inferred from bradycardia after treatment with the adrenergic neuron-blocking agent, bretylium tosylate.
(15) These results clearly indicate that in both intact and OVX does, endogenous NPY is in part responsible for maintaining basal, tonic LH secretion.
(16) All motoneuron firing during fictive swimming is associated with a tonic depolarization that falls away slowly once firing stops, is increased by hyperpolarizing current, and is reduced by depolarizing current.
(17) The tonic influences were expressed in an increase in the amplitude parameters of the responses of the visual cortex in conditions of the formation in the posterolateral nucleus of the thalamus of a focus of heightened excitability (anode polarization), and their perceptible diminution with potassium depression in this nucleus.
(18) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(19) During each session, measurements were made of either tonic accommodation or tonic vergence 30 s before stimulus onset and at 0.5, 2, 4, 6, 8, 10, 12, and 14 min after stimulus offset.
(20) The findings can be summarized as follows: (1) The effective concentration of SDS for termination of shark tonic immobility (an immediate and fast response) was close to its critical micellar concentration in sea water (70 microM).