(v. t.) To set on fire; to cause to burn with flame; to ignite; to cause to begin burning; to start; to light; as, to kindle a match, or shavings.
(v. t.) Fig.: To inflame, as the passions; to rouse; to provoke; to excite to action; to heat; to fire; to animate; to incite; as, to kindle anger or wrath; to kindle the flame of love, or love into a flame.
(v. i.) To take fire; to begin to burn with flame; to start as a flame.
(v. i.) Fig.: To begin to be excited; to grow warm or animated; to be roused or exasperated.
Example Sentences:
(1) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(2) For the purpose of contributing methodologically to experimental research on epilepsy, we investigated whether a difference exists in kindling development between acute and chronic preparations using identical species of animals, kindled brain tissues, stimulus intervals, and intensities.
(3) The kainate and quisqualate types of excitatory amino acid receptor were visualized autoradiographically in brain sections from rats kindled by stimulating the angular bundle.
(4) A corrective effect of Nicotinamide on oxidation processes in ganglion and neuroglial cells of cerebral cortex sensorimotor zone in "kindling" phenomenon was studied in the experiments on mice of C57BL line.
(5) PHT, CBZ, VPA, and CZP, SK&F 89976-A and SK&F 100330-A inhibited seizures in corneally kindled rats.
(6) The inhibitory effect of serotonin on the kindling model of epilepsy was investigated in the adult rat.
(7) In the second experiment, 15- and 30-day-old rats underwent unilateral carotid ligation followed by kindling in the ipsilateral amygdala.
(8) If Obama is your new iPad, Sarah Palin is your old Kindle.
(9) Electrical amygdaloid kindling was carried out with a 15 min inter-stimulus interval (ISI) in a control situation with intravenous (i.v.)
(10) We suggest that the NE-dependent mechanism responsible for the seizure suppression observed to follow concurrent, alternate stimulation and the suppression of seizure development using single-site kindling paradigms may be the same.
(11) GABAergic neurons and terminals are also increased in the hippocampus of seizure-sensitive gerbils, and kindling of the hippocampus and amygdala appears to enhance GABAergic inhibitory mechanisms.
(12) Based on an hypothesis that links electrical kindling in the limbic system (leading to seizures) to reverse tolerance or sensitivity to cocaine's effects, carbamazepine is being tested as a treatment for human cocaine users.
(13) reversed the increase in locomotion and elevation of multiple squeak thresholds in the bilaterally kindled rats.
(14) In fully kindled animals a stimulus-induced generalized seizure gave rise to a three-fold increase of noradrenaline levels in the stimulated hippocampus as compared to baseline levels (15-min samples).
(15) In the present work no significant differences were found between the behaviour of FG7142-kindled rats and vehicle-treated controls in social interaction test, elevated plus maze, or the Vogel conflict test of anxiety or in tests of home cage aggression or startle responses.
(16) Amygdaloid kindling of rats produced an increase in hippocampal Met5-enkephalin-Arg6-Gly7-Leu8 and cholecystokinin immunoreactivities and simultaneously a decrease in dynorphin A1-8 content.
(17) The data suggest that GABA-T inhibitors, such as vigabatrin, differ from most antiepileptic drugs previously tested in the kindling model in that they may produce both anticonvulsant and proconvulsant effects at the same dose in the same animal as a function of time after administration.
(18) However, the concentration of Asp decreased depending on the kindling stage, reaching the lowest value of 33% in comparison with the normal value.
(19) Thus, electrophysiological alterations within the first synaptic relay of the hippocampal trisynaptic circuit, the dentate gyrus, cannot explain the long duration of the kindling effect.
(20) In brightness discrimination reaction (BDR) the learning performance of PTZ-kindled animals was not influenced.
Sear
Definition:
(a.) To wither; to dry up.
(a.) Alt. of Sere
(a.) To burn (the surface of) to dryness and hardness; to cauterize; to expose to a degree of heat such as changes the color or the hardness and texture of the surface; to scorch; to make callous; as, to sear the skin or flesh. Also used figuratively.
(n.) The catch in a gunlock by which the hammer is held cocked or half cocked.
Example Sentences:
(1) Just a few months ago, a director-level position job for Sears was floated by me from the department store chain's headquarters in Chicago.
(2) They revealed that Lance Corporal Craig Roberts, who died in searing temperatures on the Brecon Beacons, had been about to begin a new post in the office of the education secretary.
(3) It feels very much like the work of a cook born in Bordeaux, the place where they like to top their cote de boeuf with bone marrow, and sear it fast so that inside it is still the colour of raging knife cut.
(4) A confrontation between French and German passengers appears to resonate with disputes and tensions within the family; archive film shows searing images from the second world war, from Israel and Palestine, from the modern-day Odessa Steps.
(5) A Communist party-controlled newspaper has launched a searing attack on Donald Trump after the president-elect threatened a realignment of his country’s policies towards China, warning the US president-elect: “Pride goes before a fall.” The Global Times, a notoriously rambunctious state-run tabloid, was writing after Trump reignited a simmering row with Beijing by suggesting he might recognise Taiwan , which China regards as a breakaway province, unless Beijing agreed a new “deal” with his administration.
(6) That searing experience continues to shape the thinking of a generation of policymakers and peacemakers anxious that there should not be "another Rwanda" on their watch.
(7) Or take a free elevator ride to the roof of the old Sears Roebuck building ( southsideonlamar.com ) which is now loft housing.
(8) Through the searing summer heat, the Mexican immigrant to California’s Central Valley and his family endured a daily routine of collecting water in his pickup truck from an emergency communal tank, washing from buckets and struggling to keep their withering orchard alive while they waited for snow to return to the mountains and begin the cycle of replenishing the aquifer that provides water to almost all the homes in the region.
(9) A t the end of the long day's walk under the searing Moroccan sun, across endless expanses of sand, the Berbers slowed their camel and stopped.
(10) Woman in the Crossfire: Diaries of the Syrian Revolution documents the first months of the uprising, and The Crossing: My Journey to the Shattered Heart of Syria describes in searing prose her return visits to the “liberated” but bombed and fiercely contested north.
(11) First there was the one whipped up by the invasive glare of the TV cameras, zooming in on the respective engagement rings of Sears and Ester Satorova, Berdych’s fiancee.
(12) His condemnation of existing arrangements is the most searing criticism from the business establishment since Richard Lambert, then director-general of the Confederation of British Industry, two years ago warned bosses risked being viewed as "aliens [living in] a different galaxy from the rest of the community" because of the ever widening gulf between shopfloor and boardroom wages.
(13) The British No1 gestured to his courtside box, where Sears was filmed mouthing what appeared to be the words “fucking have it you Czech flash fuck” apparently in the direction of Berdych’s team.
(14) A theoretical analysis of pathway and kinetic cooperatively in this system is presented in the following paper (Sears, D.W., and Beychok, S. (1977), Biochemistry 16 (following paper in this issue)).
(15) Perhaps it was the searing heat , or perhaps it was the American magician dangling outside Tower Bridge in a box.
(16) Boeing is said to hope that Mr Sears's guilty plea will put an end to the scandal and revive the refuelling contract, which was put on ice by the US defence secretary, Donald Rumsfeld.
(17) But first, following the searing criticism he directed at UK Athletics for its “ridiculous and wrong” decision to omit the union flag from the vests to be worn by British athletes , the 28-year-old talks far more personally and bitingly.
(18) Republicans stake their claim as Christie stresses credentials at CPAC Read more The 2015 Conservative Political Action Conference was in full swing, and at the end of Thursday afternoon, the crowd got what it had come for, in spades: three searing speeches from the main stage razzing President Barack Obama, damning “radical Islamic terrorism” and celebrating the United States as the best place on Earth in history.
(19) Documents found in the rubble of the Tazreen factory showed that garment users supplying goods to Walmart and Sears were using the plant at the time of the fire.
(20) Razor-sharp analysis and forensic questioning are her weapons, while jargon-free indignation sears her criticisms on the public mind.