What's the difference between kindred and unkindred?
Kindred
Definition:
(n.) Relationship by birth or marriage; consanguinity; affinity; kin.
(n.) Relatives by blood or marriage, more properly the former; relations; persons related to each other.
(a.) Related; congenial; of the like nature or properties; as, kindred souls; kindred skies; kindred propositions.
Example Sentences:
(1) No woman is at greater risk for ovarian carcinoma than one who is a member of a hereditary ovarian carcinoma syndrome kindred and whose mother, sister, or daughter has been affected with this disease and with an integrally related hereditary syndrome cancer.
(2) An unusual spectrum of craniofacial and foot abnormalities has been detected within a large midwestern Amish kindred.
(3) 45Calcium has been used to compare the kinetics for the transport and bioaccumulation of this regulatory cation in keratinocyte cultures of a kindred with HPS (i.e., one HPS homozygote, one HPS obligate heterozygote, one normal family member, and healthy adult controls).
(4) In this study, six patients, the proband, his four siblings and a niece, representing a kindred of fifty-two subjects, were examined for aymptomatic cutaneous nodules mainly on the back and chest.
(5) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).
(6) A four-generation 25-member kindred with Factor XI:C deficiency is reported.
(7) In a nationwide investigation in South Africa, 25 affected individuals in 15 Afrikaner kindreds have been studied.
(8) found linkage between manic depression and HRAS1 in a single large Amish kindred.
(9) Longevity analysis demonstrated elongation of life expectancy for kindred members, and there was an apparent rarity of premature cardiac events.
(10) The logarithm of the odds ratio between GTHR and c-erbA beta was 3.67, and therefore GTHR mapped to the c-erbA beta locus in this kindred.
(11) To investigate the possibility that the syndrome is caused by mutation in a tumor suppressor gene, we searched for loss of heterozygosity in 16 sporadic basal cell carcinomas, 2 hereditary basal cell carcinomas, and 1 hereditary ovarian fibroma and performed genetic linkage studies in five Gorlin syndrome kindreds.
(12) In the present study, we have analyzed the IF staining patterns of skin and fibroblast cultures from Marfan syndrome patients and normal first-degree relatives in nine Marfan kindreds.
(13) Consanguinity of the kindreds could not be established.
(14) Here we demonstrate that in this kindred, which shows linkage to chromosome 21 markers, there is a point mutation in the APP gene.
(15) It also abolishes the Aval site (CTCGGG) in exon VI, which can be directly detected with the enzymatic DNA amplification technique (PCR) and offers the possibility of direct analysis in carrier and prenatal diagnosis in kindreds with this mutation.
(16) Kindred S showed the effect in man of heterozygous and homozygous expression of a dominant negative form of c-erbA beta.
(17) Lifetime risk of dementia in early-onset FAD kindreds is consistent with an autosomal dominant inheritance model.
(18) A kindred with an X-autosome translocation and differential inactivation of the X chromosome is described.
(19) Depending on the size of the kindred, the pedigree automatically obtains a rectangular or circular appearance.
(20) The W family represents the largest such North American kindred yet reported.