(n.) The stoke of a bell tolled at a funeral or at the death of a person; a death signal; a passing bell; hence, figuratively, a warning of, or a sound indicating, the passing away of anything.
(n.) To sound as a knell; especially, to toll at a death or funeral; hence, to sound as a warning or evil omen.
(v. t.) To summon, as by a knell.
Example Sentences:
(1) The BBC Trust The green paper sounds the death knell for the BBC’s current governance system in the form of the BBC Trust, which it says has come under “sustained criticism” as a result of the Savile scandal, the £100m Digital Media Initiative fiasco and excessive payoffs and salaries to BBC executives.
(2) He said: "If Heathrow builds its runway, it will be the death knell of low-cost flying for a generation."
(3) In the Commons yesterday all the former ministers were rounded on by a succession of Labour MPs claiming the moment marked the death knell of New Labour.
(4) Fashion's current preoccupation with art is effectively the death knell of the minimalist look – most art (Donald Judd and his ilk aside) is about getting messy.
(5) The return of the jihadists is likely to sound the death knell for the anti-regime opposition in north Syria.
(6) Brexit may sound the death knell for this progress.
(7) Saleh's return to Yemen after more than three months would seem to sound the death knell for the exit plan and the start of a bid to consolidate his ruling party's power base, which crumbled in his absence.
(8) You are neither the death knell for immigration reform nor the prime mover of the GOP agenda.
(9) "As such, it is highly likely the chancellor's annuity announcement will also turn out to be disastrous for first-time buyers and could represent the death knell of aspirations of homeownership for millions of young families.
(10) It will be the death knell for the whole Scottish literature "project" – a crushing denial of an identity that writers have been meticulously accumulating, trying to maintain and refine.
(11) Last Post in Iraq: this is the death knell of the American empire | George Galloway Read more Gen Bednarek adds: “The tougher issue will be, ‘what’s next?’ We must have local Sunni police and our tribes of Falluja sustain the fragile security, re-establish governance, and provide for the people,” he says.
(12) The regime’s offensive has been seen in the opposition-held north as a death knell for the UN deal, negotiated by its special envoy Staffan de Mistura, for a six-week ceasefire in the city.
(13) His comments were seen by some as sounding the death knell of the plan.
(14) And while the poll tax may be beyond the memory of most active politicians (the infamous riot that sounded its death knell took place 24 years ago this week) its consequences live on, from a contributory role in Mrs Thatcher's downfall to a massive and damaging centralisation of funding for local councils.
(15) In what some have described the death-knell for “Abenomics” – his three-arrow policy of monetary easing, fiscal stimulus and structural reform – recent currency and market turmoil have wiped out the gains made soon after he became prime minister in late 2012.
(16) However, the switch to refrigerated lorries and growth in supermarket power sounded the death knell for many of these smaller farms, with the number of dairy farmers falling from 200,000 in the 1950s to around 10,000 today.
(17) The Department of Health last month publicly sounded the death knell for Labour's ill-fated £11.4bn national programme for IT, which began in 2002 and was said to be the largest civilian computer project ever undertaken.
(18) In what was being seen in Westminster last night as the death knell of New Labour and a return to a form of traditional left-right politics, Darling became the first chancellor since the 1970s to announce income tax increases, and also scrapped Gordon Brown's fiscal rules to sanction a doubling of borrowing this year.
(19) The changing nature of the labour market in the final quarter of the 20th century sounded the death knell for the old job for life and the smooth career progression, but, says Reeves, the self-employment model characterised by WVM provided a means of upward mobility.
(20) It will not just be the death knell for the farm but the death knell for the whole community,” said Alan Davies, managing director of the FUW.
Slowly
Definition:
(adv.) In a slow manner; moderately; not rapidly; not early; not rashly; not readly; tardly.
Example Sentences:
(1) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(2) The adaptive filter processor was tested for retrospective identification of artifacts in 20 male volunteers who performed the following specific movements between epochs of quiet, supine breathing: raising arms and legs (slowly, quickly, once, and several times), sitting up, breathing deeply and rapidly, and rolling from a supine to a lateral decubitus position.
(3) In the patients who have died or have been classified as slowly progressive the serum 19-9 changes ranged from +13% to +707%.
(4) We conclude that the rat somatosympathetic reflex consists of an early excitatory component due to the early activation of RVL-spinal sympathoexcitatory neurons with rapidly conducting axons and a later peak that may arise from the late activation of these same neurons as well as the early activation of RVL vasomotor neurons with more slowly conducting spinal axons.
(5) In the dark the 6-azidoflavoproteins are quite stable, except for L-lactate oxidase, where spontaneous conversion to the 6-amino-FMN enzyme occurs slowly at pH 7.
(6) Gradual evolutionary change by natural selection operates so slowly within established species that it cannot account for the major features of evolution.
(7) To gain more information about sources of activator Ca2+ involved in the contraction of rat and guinea-pig aorta evoked by angiotensin II and their sensitivity to Ca2+ entry blockers, measurement of slowly exchanging 45Ca2+ was established.
(8) Sorbitol, by itself or in combination with mannitol is slowly converted to acids by the plaque microorganisms.
(9) In contrast, T lymphocyte cytolytic activity developed more slowly in regressing sarcomas and attained peak levels coincident with the beginning of tumor regression.
(10) Testosterone was low until 68 weeks after which concentrations rose slowly to 80 weeks and increased rapidly to a plateau at 92 weeks.
(11) Also blacks differ from whites in 2 ways that could be relevant for their increased prevalence of hypertension: they excrete sodium loads more slowly and have a markedly lower urinary kallikrein.
(12) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(13) This decrease was due in part to formation of slowly dissociating cell surface receptor [3H]BK binding and in part to internalization of the receptor-bound [3H]BK.
(14) Strains lacking the A form of eIF-5A, constructed by disruption of TIF51A with LEU2, grow slowly, whereas strains lacking the B form, in which HIS3 was used to disrupt TIF51B, show no growth rate phenotype.
(15) Although differences were noted between species, the absolute rates of absorption measured indicate that the phthalate esters are slowly absorbed through both human and rat skin.
(16) In some patients stimulation can reduce rigidity and coactivation of muscles immediately or slowly over days or months.
(17) The kinetics of association of the radioligand suggested the presence of a rapidly associating, reversible binding site, and a slowly associating, apparently irreversible one.
(18) A fat emulsion when injected into tissue is scarcely taken up by the blood vascular system but is retained within the tissue over a relatively extended period, and is distributed slowly into the surrounding tissues and to the regional lymph nodes.
(19) It is suggested that an enzyme-inhibitor complex of an acyl-enzyme type is formed that is slowly hydrolysed, with water as the final acceptor, leaving an intact enzyme and an inactive form of the inhibitor.
(20) There is extant a population of subjects who have average or better than average interpretive reading skills as measured by standardized tests but who read slowly and inefficiently.