(n.) The stoke of a bell tolled at a funeral or at the death of a person; a death signal; a passing bell; hence, figuratively, a warning of, or a sound indicating, the passing away of anything.
(n.) To sound as a knell; especially, to toll at a death or funeral; hence, to sound as a warning or evil omen.
(v. t.) To summon, as by a knell.
Example Sentences:
(1) The BBC Trust The green paper sounds the death knell for the BBC’s current governance system in the form of the BBC Trust, which it says has come under “sustained criticism” as a result of the Savile scandal, the £100m Digital Media Initiative fiasco and excessive payoffs and salaries to BBC executives.
(2) He said: "If Heathrow builds its runway, it will be the death knell of low-cost flying for a generation."
(3) In the Commons yesterday all the former ministers were rounded on by a succession of Labour MPs claiming the moment marked the death knell of New Labour.
(4) Fashion's current preoccupation with art is effectively the death knell of the minimalist look – most art (Donald Judd and his ilk aside) is about getting messy.
(5) The return of the jihadists is likely to sound the death knell for the anti-regime opposition in north Syria.
(6) Brexit may sound the death knell for this progress.
(7) Saleh's return to Yemen after more than three months would seem to sound the death knell for the exit plan and the start of a bid to consolidate his ruling party's power base, which crumbled in his absence.
(8) You are neither the death knell for immigration reform nor the prime mover of the GOP agenda.
(9) "As such, it is highly likely the chancellor's annuity announcement will also turn out to be disastrous for first-time buyers and could represent the death knell of aspirations of homeownership for millions of young families.
(10) It will be the death knell for the whole Scottish literature "project" – a crushing denial of an identity that writers have been meticulously accumulating, trying to maintain and refine.
(11) Last Post in Iraq: this is the death knell of the American empire | George Galloway Read more Gen Bednarek adds: “The tougher issue will be, ‘what’s next?’ We must have local Sunni police and our tribes of Falluja sustain the fragile security, re-establish governance, and provide for the people,” he says.
(12) The regime’s offensive has been seen in the opposition-held north as a death knell for the UN deal, negotiated by its special envoy Staffan de Mistura, for a six-week ceasefire in the city.
(13) His comments were seen by some as sounding the death knell of the plan.
(14) And while the poll tax may be beyond the memory of most active politicians (the infamous riot that sounded its death knell took place 24 years ago this week) its consequences live on, from a contributory role in Mrs Thatcher's downfall to a massive and damaging centralisation of funding for local councils.
(15) In what some have described the death-knell for “Abenomics” – his three-arrow policy of monetary easing, fiscal stimulus and structural reform – recent currency and market turmoil have wiped out the gains made soon after he became prime minister in late 2012.
(16) However, the switch to refrigerated lorries and growth in supermarket power sounded the death knell for many of these smaller farms, with the number of dairy farmers falling from 200,000 in the 1950s to around 10,000 today.
(17) The Department of Health last month publicly sounded the death knell for Labour's ill-fated £11.4bn national programme for IT, which began in 2002 and was said to be the largest civilian computer project ever undertaken.
(18) In what was being seen in Westminster last night as the death knell of New Labour and a return to a form of traditional left-right politics, Darling became the first chancellor since the 1970s to announce income tax increases, and also scrapped Gordon Brown's fiscal rules to sanction a doubling of borrowing this year.
(19) The changing nature of the labour market in the final quarter of the 20th century sounded the death knell for the old job for life and the smooth career progression, but, says Reeves, the self-employment model characterised by WVM provided a means of upward mobility.
(20) It will not just be the death knell for the farm but the death knell for the whole community,” said Alan Davies, managing director of the FUW.
Snell
Definition:
(a.) Active; brisk; nimble; quick; sharp.
(n.) A short line of horsehair, gut, etc., by which a fishhook is attached to a longer line.
Example Sentences:
(1) The above results suggest that hormone deficiency in Snell dwarf mice is a result of a defect in the hormone-producing cells in the gland.
(2) Expressions for the parameters are from by the application of Markov's theory of chains which was developed by Kemeny & Snell (1960, Finite Markov Chains, Princeton, NJ: Van Nostrand) and Bosso et al.
(3) On addition of monovalent cation to the holoenzyme-ethionine complex, a marked increase occurs in absorption of 508 nm resulting from labilization of the alpha proton with formation of the quinoid form of the pyridoxal phosphate moiety of the enzyme-substrate complex at the catalytic center (Morino, Y., and Snell, E.E.
(4) The chromosomes involved in the T(2;4)Sn (formerly designated T(5;8) Sn) or Snell translocation in the mouse have been identified as numbers 2 and 4 by analysis of the fluorescent banding patterns of quinacrine mustard-stained chromosomes in primary cultures from heterozygous and homozygous embryos.
(5) The concentration of gangliosides in the Snell dwarf mouse cerebrum was monitored from postnatal day 5 to day 40.
(6) Pituitary dwarf mutants of the Snell-Bagg and Ames mouse strains develop severe immunodeficiency of the thymus-dependent system which frequently leads to a fatal wasting syndrome.
(7) If the four known pyruvoyl-dependent HisDCases arise from inactive proenzymes by the mechanism previously demonstrated for the HisDCase of Lactobacillus 30a (Recsei, P. A., Huynh, Q. K. and Snell, E. E. (1983) Proc.
(8) Snell called upon testimony from Los Angeles mayor Tom Bradley, which he gave in absentia but in unambiguous terms, describing GM as having, through its subsidiaries, “scrapped the Pacific Electric and Los Angeles streetcar systems, leaving the electric train system totally destroyed.” GM, in the face of such harsh accusations, made no recorded public response except to admit to its investment in American City Lines, a company with which National City Lines merged in 1946.
(9) Thus bacterially synthesized hGH behaves identically to pituitary-derived hGH with respect to body length, sulfate incorporation into costal and epiphyseal cartilage, body weight and organ growth of Snell dwarf mice, with one exception: increase of weight of the kidneys, as a function of body weight, was more pronounced after treatment with hGH than with bhGH.
(10) It’s a brilliant mix of backpacking, volunteering and surfing – and what’s even better is you might get a qualification at the end of it,” says Jennifer Snell, 20, from Wiltshire, who combined an office job with working as a fishmonger in Tesco to raise the money.
(11) Refraction effects from planar tissue layer interfaces are analyzed using Snell's law and measured using phantoms.
(12) Congenital deficiency of growth hormone, prolactin, and TSH was first described in Snell dwarf mice.
(13) These diseases are highly infectious, very difficult to treat and can have severe complications, particularly in children, but they are vaccine-preventable,” the South Australian health minister, Jack Snelling, told reporters on Friday.
(14) In the last decade this work culminated in the close study of the Little Mouse with isolated growth hormone deficiency--thus exposing the panhypopituitary model (the human pituitary dwarf, Snell Smith mouse or hypophysectomised rat) as non-optimal models.
(15) Adrenocorticotrophin (ACTH) produced an insignificant stimulation of pregnenolone biosynthesis from endogenous precursors in isolated cells prepared from the rat Snell adrenal carcinoma 494.
(16) Formation of these two products supports a previously proposed mechanism of inactivation (Hayashi, H., Tanase, S., and Snell, E. E. (1986) J. Biol.
(17) The results indicate that dopaminergic A12 neurons in Snell dwarf mice are present and viable.
(18) No differences in metabolism of [7alpha-(3)H]dehydroepiandrosterone or [4-(14)C]pregnenolone were detected between adrenal tissue from Sprague-Dawley, Wistar and Osborne-Mendel rats, but experiments with the Snell rat adrenocortical tumour 494 showed that this tissue had low 5alpha-reductase activity.
(19) While at the museum I spent some time talking to geologist Andrew Snelling.
(20) originally designated (H. Kagamiyama, H. Wada, H. Matsubara, and E. E. Snell, 1972, J. Biol.