(n.) An instrument consisting of a thin blade, usually of steel and having a sharp edge for cutting, fastened to a handle, but of many different forms and names for different uses; as, table knife, drawing knife, putty knife, pallet knife, pocketknife, penknife, chopping knife, etc..
(n.) A sword or dagger.
(v. t.) To prune with the knife.
(v. t.) To cut or stab with a knife.
Example Sentences:
(1) "I pulled the microphone in front of my seat, not a knife.
(2) Leicester looked a little sorry for themselves and, with their concentration down, United twisted the knife.
(3) Frontal afferents to the medial basal hypothalamus of the rat were interrupted by a Halász knife, and 4 weeks later the brains were processed for immunostaining of CRF-fibers.
(4) Earlier this year the Guardian launched Beyond the Blade , a long-term project looking at young people who are victims of knife crime.
(5) When we reached our summit, or whatever spot was deemed by my father to be of adequately punishing distance from the car to deserve lunch, Dad would invariably find he had forgotten his Swiss army knife (looking back, I begin to doubt he ever had one) and instead would cut cheese into slices with the edge of his credit card.
(6) More conservative approaches have been used in young women requesting preservation of their childbearing ability, including CO2 laser excision, knife excision, cryotherapy, and electrocauterization.
(7) One day, a man she had interviewed held a knife to her throat, holding her captive for 10 days and only releasing her when the French embassy came looking for her.
(8) In the wake of a second fatal police shooting in the St Louis area after the death of Michael Brown , concerned citizens are asking why officers had to kill Kajieme Powell, a 25-year-old man who was holding a knife and “behaving erratically.” They want to know why officers don’t shoot someone like Powell in the leg or the arm, rather than aiming for vital organs, or why they don’t just use a less lethal weapon, like a Taser.
(9) At home, he’s besieged by leadership speculation of sufficient intensity to see his conservative allies resort to public verbal knife-fights.
(10) When it's serving time, use a good serrated knife to saw cleanly through the rhubarb.
(11) I don’t remember what happened afterward.” By morning, Israeli newspapers had published the official version of Anas al-Atrash’s death: A 23-year-old Palestinian had run from his car and rushed at a checkpoint soldier with a knife.
(12) A disproportionate number of those who are victims and perpetrators of knife crime are African-Caribbean.
(13) It also said that night that the suspect had been unarmed — an assertion that was revealed to be false the next day when officials acknowledged Gonzalez had a knife with him when he was apprehended.
(14) Hogan-Howe waded into the row, saying gang members heard simple messages such as that there was a minimum five-year jail sentence for possession of a gun, but had no idea about the equivalent sentence for carrying a knife.
(15) With it sank my suitcase of clothes and my striped prisoner uniform, including my hat, coat, shirt and a knife.
(16) Albeit an unloveable, slightly scary Ron Burgundy in a 'I may now be a low level Tesco manager in a cheap suit but I still remember how to handle a stanley knife' kind of way," reckons Robert Lowery, who is forgetting that Jim White has a phone.
(17) He didn't even mind the National Front turning up and sieg-heiling during gigs, which seems enormously sporting of him, given his raft of horrifying stories about experiencing racism in 60s and 70s Britain, and the scars he still bears as the result of a racially motivated 1980 knife attack.
(18) Lysine vasopressin and a long-acting analogue N alpha-triglycyl-lysine vasopressin were compared in a prospective randomized double-blind study including 71 women undergoing cold knife conization of the uterine cervix.
(19) There was a 24% rise in knife crime in London in the 12 months ending in March.
(20) Once, the inquest heard, he threatened Luke’s football coach, telling him: “I have a knife with your name on it.” When Anderson killed Luke there were four warrants out for his arrest including one related to his possession of child sex abuse images.
Nep
Definition:
(n.) Catnip.
Example Sentences:
(1) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(2) These data indicate that mammalian tachykinins induce the release of NCA from BBEC and that NEP modulates these effects.
(3) The nuclear masses are known as (1) the area lateralis hypothalami (ALH), (2) the nucleus entopeduncularis (nEp), (3) the nucleus semilunaris accessorius (nSA), (4) the nucleus ventromedialis hypothalami (nVmH), and (5) the posterolateral portion of the zona incerta (ZI).
(4) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(5) These results suggest that degradation of NKA and NKB by NEP but not by ACE is an important determinant of the bronchoconstriction induced by these peptides.
(6) By cleaving and thus inactivating tachykinins released from sensory nerves, NEP limits the actions of these peptides.
(7) We gave phosphoramidon to inhibit NEP and enalapril maleate or captopril to inhibit ACE.
(8) The effects of neutral endopeptidase inhibition (NEP-I) were studied in 6 conscious sheep with heart failure (HF) induced by rapid ventricular pacing for 7 days.
(9) The present work examined the susceptibility of these novel peptides to hydrolysis by various purified exo- and endo-peptidases including endopeptidases 24.11 (NEP), 24.15, 24.16, angiotensin-converting enzyme, leucine aminopeptidase and carboxypeptidase A. NEP attacked MCH at three sites of the molecule with an apparent affinity of about 12 microM and a kcat.
(10) On the other hand, transient or enhanced expression of NEP is observed during the development of several organs such as the sensory organs, the heart and the major blood vessels, the intestine, the bones and the genital tubercle.
(11) These studies confirm the presence of neutral endopeptidase (NEP) in the nuchal ligament of the fetal calf.
(12) Regional haemodynamic responses to atrial natriuretic peptide (ANP, 0.5 nmol kg-1) or proendothelin-1 [1-38] (1.0 nmol kg-1) were assessed in the same conscious Long Evans rats before and 20 min after administration of the novel neutral endopeptidase (NEP) inhibitor, SQ 28,603 (50 mg kg-1, i.v.).
(13) The activity of NEP, measured with an enzymatic fluorimetric method employing N-dansyl-D-alanyl-glycyl-L-4-nitrophenylalanyl-glycine as a synthetic substrate, was 18 times and eight times higher in the outer stripe of the medulla and inner cortex than in the outer cortex (OC).
(14) There were no significant differences in apparent volume of distribution, elimination half-life, and elimination clearance (CIe) for nEp and rEp in intact dogs.
(15) Also examined were the effects of inhibitors of neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE).
(16) This binding was displaced in a dose-dependent manner by NEP inhibitors.
(17) Using NEP-expressing MDCK cells and episcopic fluorescence microscopy, a specific labeling was obtained with 100 nM FTI which was completely displaced by 10 microM HACBOGly, a specific and potent inhibitor of NEP.
(18) We concluded that, although covalent bonds appear to be cleaved in NEP by papain, its activity and structure are sustained by S-S bridges.
(19) To determine the distribution of NEP, a possible regulatory enzyme for the neuropeptide-induced leukocyte activation, among human leukocytes, we investigated the enzymatic activity of NEP in each cell type of human peripheral blood leukocytes.
(20) N-ethyl piperidinyl diaminodithiol (NEP-DADT), complexed with 99mTc has been developed as an agent for the measurement of brain blood flow using SPECT.