(n.) A hard protuberance; a hard swelling or rising; a bunch; a lump; as, a knob in the flesh, or on a bone.
(n.) A knoblike ornament or handle; as, the knob of a lock, door, or drawer.
(n.) A rounded hill or mountain; as, the Pilot Knob.
(n.) See Knop.
(v. i.) To grow into knobs or bunches; to become knobbed.
Example Sentences:
(1) The narrow intercellular ridge is smooth, whereas the epithelial cells have small cytoplasmic knobs between the cilia.
(2) The histochemical study of the LDH in the Trout embryo during the early organogenesis shows a specific localization in notochord cells, in mesodermic cells of the terminal knob and in some prosencephalic neuroblasts.
(3) Motor axons possessed elongate, irregularly shaped boutons en passant and morphologically variable boutons terminaux; the latter included huge endings with knobbed projectiles arising from thick collaterals, or smaller, round boutons from thin collaterals.
(4) Men might not have frills and furbelows as women traditionally do, but they’ve got spurious function: knobs on their watches or extra pockets on their jackets that are just as decorative as anything women wear.” 6.
(5) As with established cell lines, formation of zeiotic knobs at the isolated Type 1 cell surface appeared closely related to microfilamentous nets located beneath the plasmalemma.
(6) The isolated cells have an ovoid soma, a dendrite of variable length which terminates in a cilia-bearing knob and an axon, also of variable length.
(7) In addition, some reacted with either knob protrusions or caveolae of the host erythrocyte membrane; one reacted with a parasite-derived antigen present in the erythrocyte cytoplasm.
(8) "It might be that you think it's just a knob on the front panel, but maybe installing it requires you disassemble the front panel, and actually you need a mechanic to come and fit it," argues Rowley.
(9) wt from 80 to 95 kd in different knob-producing isolates of P. falciparum and is absent in knobless variants.
(10) To investigate environmental influences on the development of the olfactory epithelium, semi-thin sections were taken from the nasal septum of newborn and 30-day-old rabbits; the epithelial thickness and the number of olfactory knobs, supporting cells, dark basal cells, and receptor cells were compared.
(11) The spores of Rif-18 are pleomorphic and frequently exhibit terminal knobs.
(12) To investigate the involvement of actin filaments in concanavalin A (Con A)-induced cap formation and cytochalasin B (CB)-induced zeiotic knob migration, the distribution of F-actin was studied in Con A-treated and CB-treated Ehrlich ascites tumor cells (EATC) by fluorescence microscopy using heavy meromyosin conjugated with a fluorescent dye, N-(7-dimethylamino-4-methylcoumarinyl) maleimide, (DACM-HMM).
(13) 205 subjects each chose a "most pleasant" sound delivered through an earphone by turning the control knob on a continuously variable audio oscillator.
(14) Knobs which appear on the membrane of the infected erythrocytes adhere to the endothelium, causing the obstruction of cerebral microvessels.
(15) Cytoadherence of infected erythrocytes in vivo is associated with the presence of knobs on the erythrocyte surface, but we and others have shown recently that cytoadherence to C32 melanoma cells may occur in vitro in the absence of knobs.
(16) Systemic administration of the anti-inflammatory agent indomethacin blocked vascular leakage due to endothelial gap formation but had little or no effect on trophoblast knob penetration of vessels.
(17) After crossectomy which remains the most important stage, a short stripping is performed in an upward direction, substituting a packing for the olive shaped knob normally used.
(18) Under scanning electron microscopy, O. viverrini eggs looked like musk-melon skin; they had prominent shoulders and long knobs.
(19) Six culture-adapted knob-positive Plasmodium falciparum parasites, four of which were nonbinding in an in vitro cytoadherence assay, were tested for the presence of the knob-associated histidine-rich protein PfHRP1.
(20) Instead, there were free and spiral nerve terminals in the interstitium, and epilemmal knob-like or bouton-like endings surrounding non-encapsulated muscle fibers.
Kob
Definition:
(n.) Alt. of Koba
Example Sentences:
(1) The transition was characterized by a single first order rate constant (kobs,i) which was independent of enzyme concentration.
(2) Knowledge of the salt dependences of ka and of the observed equilibrium constance Kobs of the ligand-nucleic acid interaction should usually be sufficient to determine whether a screening controlled mechanism or a pre-equilibrium mechanism is suitable to describe the process.
(3) A log kobs versus pH profile for the approach to the ionization equilibrium was determined, and a mechanism consistent with the profile was postulated.
(4) In the absence of cyanide, ferrocytochrome a3 appears at a rate (kobs) of 0.016 s-1.
(5) Above 25 microM AT.H complex, an increasing dead time displacement of p-aminobenzamidine and a downward deviation of kobs from the initial linear dependence on AT.H complex concentration were found, reflecting the saturation of an intermediate Xa.AT.H complex with a KD of 200 microM and a limiting rate of Xa-AT product complex formation of 140 s-1.
(6) At pH 7.8, the apparent single rate constant for association (kobs) at 4 degrees C was 4.72 x 10(+5).M-1.min-1.
(7) Thus, under pseudo-first order conditions ([AT]o, [H]o much greater than [T]o much less than [P]o), the observed thrombin inactivation rate constant (kobs) exhibited a saturable dependence on [AT]o or [H]o when [H]o much less than KT,H, reflecting a KAT,H (0.25 microM) similar to that directly determined by equilibrium binding.
(8) The nature of the anion often has a major effect on the magnitude of the equilibrium constant (Kobs) and rate constant (kobs) of protein-DNA interactions, but a minor effect on SKobs and Skobs, which are dominated by the cation stoichiometry.
(9) The rate constant (kobs) for loss of ADP activation exhibits a nonlinear dependence on 2-BDB-TAMP concentration, suggesting a reversible binding of reagent (KR = 0.74 mM) prior to irreversible modification.
(10) The kobs max value in tissues from insulin-dependent diabetic patients was significantly greater than that in tissues from either noninsulin-dependent diabetics or nondiabetics.
(11) Reduction by lumiflavin semiquinone followed single exponential kinetics and the observed rate constant (kobs) was linearly dependent on protein concentration (k = 1.8 X 10(7) M-1s-1 heme-1).
(12) At 0.25 M-KX, the increase in Kobs for Osym is observed to be approximately 40-fold, whereas for non-operator DNA the increase in Kobs is estimated by extrapolation to be approximately 300-fold.
(13) The Kobs of this reaction reflects the difference between the observed standard free energy change (delta G-oobs) for the hydrolysis of acetylcholine and the delta G-oobs for the hydrolysis of acetyl-CoA.
(14) The observed equilibrium constants (Kobs) of the creatine kinase (EC 2.7.3.2), myokinase (EC 2.7.4.3), glucose-6-phosphatase (EC 3.1.3.9), and fructose-1,6-diphosphatase (EC 3.1.3.11) reactions have been determined at 38 degrees C, pH 7.0, ionic strength 0.25, and varying free magnesium concentrations.
(15) Stopped-flow spectrophotometry also showed that electron transfer from the Fe-protein to the MoFe-protein in states E0 and E1H occurs at the same rate (kobs.
(16) A study of kobs vs pH suggests this active-site lysine has a pKa of 8.1 and a pH-independent rate constant of inactivation of 47,700 M-1 min-1.
(17) At all temperatures, the pH strongly influenced the observed degradation rate constant (kobs) values, with rate minima observed near pH 4.
(18) Alkylation of the N-terminal half resulted in biphasic calcium release with rates (kobs 153 s-1 and 10.9 s-1 respectively) similar to those observed in intact alkylated calmodulin.
(19) At 1.2 mM 2-BDB-TAMP, kobs = 0.060 min-1 and is not affected by alpha-ketoglutarate or GTP, but is decreased to 0.020 min-1 by 5 mM NADH and to zero by 5 mM ADP.
(20) A plot of the pseudo-first order rate constant (Kobs) versus T1K concentration was linear, and values for the association (k1) and dissociation (k-1) rate constants were obtained.