What's the difference between knobby and knoblike?
Knobby
Definition:
(a.) Full of, or covered with, knobs or hard protuberances.
(a.) Irregular; stubborn in particulars.
(a.) Abounding in rounded hills or mountains; hilly.
Example Sentences:
(1) Uninfected erythrocytes incubated in culture and erythrocytes infected with early or late forms of the knobless clones or the early forms of the knobby clone all failed to obstruct the microcirculation, although exhibiting various effects on bulk viscosity and peripheral resistance during flow.
(2) Other blebs were larger, more elongate, and less knobby, but had a similar ultrastructural organization.
(3) Indirect immunofluorescence, using affinity-purified monospecific antibodies directed against recombinant protein synthesized in Escherichia coli, localized the knob-associated histidine-rich protein to the membrane of knobby infected erythrocytes.
(4) Atypical, short, knobby mycelia with radiating projections were seen in nodular lesions in the lung.
(5) In the vas deferens, the knobby fibers, the diameters of which are multiples of that of the basic one, can be converted to single units by increasing the ionic strength.
(6) The nucleolar fibres in both the core and peripheral regions were irregular and knobby, with a diameter of about 15 nm.
(7) Binding of both knobby and knobless infected erythrocytes to autologous leukocytes including monocytes, neutrophils, lymphocytes and plasma cells was found in some of the primary in vitro cultures.
(8) The only gross morphologic change in stifle joints with a severed ligament was enlarged knobby remnants of the CaCL.
(9) Differential screening of cDNA libraries constructed from knobby and predominantly knobless Plasmodium falciparum isolates, identified the sequence SD17.
(10) These proteins appeared to be aggregated or condensed in the area of the knob, whereas the remainder of the red cell surface showed no such dense clusters; haemoglobin and the histidine-rich protein of P. lophurae could not be localized to the knobby protuberances.
(11) Erythrocytes infected with a knobby variant of Plasmodium falciparum selectively bind IgG autoantibodies in normal human serum.
(12) The change from a nucleosomal organization to bundles of smooth filaments appeared to result from a complex process involving the transitory presence of conspicuous "knobby fibers" that suggest a periodicity in the organization of the spermatidal proteins along the DNA molecules.
(13) The observed alterations in P falciparum-infected red cell membrane phospholipid distribution, which is independent of the presence or absence of knobby protuberances, might be associated with the drastic changes in cell membrane permeability and susceptibility to early hemolysis observed in the late stages of parasite development.
(14) Naturally occurring anti-band 3 autoantibodies bind to erythrocytes infected with a knobby variant of the human malaria Plasmodium falciparum (FCR-3 strain).
(15) The dendrites have knobby, nodular protuberances which give them a gnarled appearance.
(16) This unusual ornamentation consists of blunt projections rising out of an otherwise smooth surface and is termed "knobby."
(17) The projection of knobby protuberances at the cell surface (zeiosis) is a general cellular response to cytochalasin D (CD), resulting from herniation of endoplasm through undefended places of the cortex during cell contractions and displacement of microfilaments induced by CD.
(18) The lowest band (band I) was found to consist of thick rod-shaped particles (330 by 80 nm) with knobby surfaces and with occasional protrusion at one end.
(19) The genomic organization of the knob protein (KP) gene of knobby (K+) and knobless (K-) variants of the Thai isolate NT 108 and the Gambian isolate FCR-3 are compared.
(20) In this study, we used the technique of whole cell mount electron microscopy to determine if the ultrastructure of the erythrocyte cytoskeleton changed following parasitization with knobby and knobless strains of P. falciparum.
Knoblike
Definition:
Example Sentences:
(1) The direct microscopic method used the polarity of the locomoting PMNs (broad, advancing lamellipodium and knoblike constriction at the rear) to record the direction of movement.
(2) Collagen type VI was detected in a loose reticular network of unbanded microfilaments that were morphologically distinguishable by knoblike protrusions every 100-110 nm.
(3) At the time of sacrifice the experimental frogs had knoblike deformities along the shafts of the long bones.
(4) At one end these fibers revealed a knoblike structure of about 10-nm diameter.
(5) The gastric glands are irregular in outline due to the knoblike projections of individual parietal cells.
(6) Four types of presumed sensory structures were observed as follow: A) ciliated knoblike papillae and B) nonciliated platelike papillae, both of which are arranged in rougly a bilaterally symmetrical pattern dorsally, ventrally, and laterally; C) rounded swellings of nonciliated papillae on the lips of the ventral and oral suckers, which are characterized in the transmission electron microscope by a rounded dense body in the apical bulb; and D) a sensory receptor with a bulbous projection having the appearance of a modified cilium, which was not found with SEM likely owing to its being enclosed by an extension of the tegument.
(7) The surface showed a honeycomb arrangement with surface protrusions 60 to 70 A long having a knoblike structure at their distal end.
(8) The envelope glycoprotein complex of Rous sarcoma virus consists of a knoblike, receptor-binding gp85 polypeptide that is linked through disulfide bonds to a membrane-spanning gp37 spike.
(9) Here we describe a spectrin isoform from Drosophila that consists of a conventional alpha spectrin subunit complexed with a novel high molecular weight beta subunit (430 kD) that we term beta H. The native alpha beta H molecule binds actin filaments with high affinity and has a typical spectrin morphology except that it is longer than most other spectrin isoforms and includes two knoblike structures that are attributed to a unique domain of the beta H subunit.
(10) This was accompanied by an actual elongation of the axopodia in specimens maintained for 20 min at 4,000 psi, but was confined to knoblike axopodial remnants in animals kept at 6,000 psi.
(11) Mitoribosomes are completely dissociated into 50S and 36S subunits at 10(-4)M MgCl(2) whereas complete dissociation of cytoribosomes into 61S and 37S subunits occurs only at 10(-6)M MgCl(2) Electron microscopy of negatively stained mitoribosomes (72S peak) shows bipartite profiles, about 265 x 210 x 200 A Characteristic views are interpreted as frontal, dorsal, and lateral projections of the particles, the latter is observed in two enantiomorphic forms Mitoribosome 50S subunits display rounded profiles bearing a conspicuous knoblike projection, reminiscent of the large bacterial subunit.
(12) Immunocytochemically, an extensive system of positive structures was found in both whole mount preparations and semithin sections, consisting of numerous varicose fibres of varying diameter and many knoblike neurosecretory terminals abutting upon the epineurium of the PO trunks.
(13) New features in the architecture of mammalian type C viruses, in particular knoblike surface projections and hexagonally arranged subunits on the core shell could be demonstrated by electron microscopy, taking advantage of newly developed preparation techniques.
(14) After excystation the juvenile's tegumental surface is characterized by knoblike protuberances and is armed almost entirely with numerous rows of small spines encircling the body.
(15) The observation of the eggs by the scanning and light microscopy revealed fine shell fenestration and a prominent knoblike spine.
(16) Electron-dense material forming knoblike particles were observed attached with a certain regularity to the inner surfaces of both junctional membranes.
(17) To obtain further information on the nature of the knoblike projections and their possible status in representing a defined spore wall ornamentation category, scanning electron micrographs and transmission electron micrographs representing all sporewall ornamentation categories were compared.