(a.) Full of, or covered with, knobs or hard protuberances.
(a.) Irregular; stubborn in particulars.
(a.) Abounding in rounded hills or mountains; hilly.
Example Sentences:
(1) Uninfected erythrocytes incubated in culture and erythrocytes infected with early or late forms of the knobless clones or the early forms of the knobby clone all failed to obstruct the microcirculation, although exhibiting various effects on bulk viscosity and peripheral resistance during flow.
(2) Other blebs were larger, more elongate, and less knobby, but had a similar ultrastructural organization.
(3) Indirect immunofluorescence, using affinity-purified monospecific antibodies directed against recombinant protein synthesized in Escherichia coli, localized the knob-associated histidine-rich protein to the membrane of knobby infected erythrocytes.
(4) Atypical, short, knobby mycelia with radiating projections were seen in nodular lesions in the lung.
(5) In the vas deferens, the knobby fibers, the diameters of which are multiples of that of the basic one, can be converted to single units by increasing the ionic strength.
(6) The nucleolar fibres in both the core and peripheral regions were irregular and knobby, with a diameter of about 15 nm.
(7) Binding of both knobby and knobless infected erythrocytes to autologous leukocytes including monocytes, neutrophils, lymphocytes and plasma cells was found in some of the primary in vitro cultures.
(8) The only gross morphologic change in stifle joints with a severed ligament was enlarged knobby remnants of the CaCL.
(9) Differential screening of cDNA libraries constructed from knobby and predominantly knobless Plasmodium falciparum isolates, identified the sequence SD17.
(10) These proteins appeared to be aggregated or condensed in the area of the knob, whereas the remainder of the red cell surface showed no such dense clusters; haemoglobin and the histidine-rich protein of P. lophurae could not be localized to the knobby protuberances.
(11) Erythrocytes infected with a knobby variant of Plasmodium falciparum selectively bind IgG autoantibodies in normal human serum.
(12) The change from a nucleosomal organization to bundles of smooth filaments appeared to result from a complex process involving the transitory presence of conspicuous "knobby fibers" that suggest a periodicity in the organization of the spermatidal proteins along the DNA molecules.
(13) The observed alterations in P falciparum-infected red cell membrane phospholipid distribution, which is independent of the presence or absence of knobby protuberances, might be associated with the drastic changes in cell membrane permeability and susceptibility to early hemolysis observed in the late stages of parasite development.
(14) Naturally occurring anti-band 3 autoantibodies bind to erythrocytes infected with a knobby variant of the human malaria Plasmodium falciparum (FCR-3 strain).
(15) The dendrites have knobby, nodular protuberances which give them a gnarled appearance.
(16) This unusual ornamentation consists of blunt projections rising out of an otherwise smooth surface and is termed "knobby."
(17) The projection of knobby protuberances at the cell surface (zeiosis) is a general cellular response to cytochalasin D (CD), resulting from herniation of endoplasm through undefended places of the cortex during cell contractions and displacement of microfilaments induced by CD.
(18) The lowest band (band I) was found to consist of thick rod-shaped particles (330 by 80 nm) with knobby surfaces and with occasional protrusion at one end.
(19) The genomic organization of the knob protein (KP) gene of knobby (K+) and knobless (K-) variants of the Thai isolate NT 108 and the Gambian isolate FCR-3 are compared.
(20) In this study, we used the technique of whole cell mount electron microscopy to determine if the ultrastructure of the erythrocyte cytoskeleton changed following parasitization with knobby and knobless strains of P. falciparum.
Snobby
Definition:
(a.) Snobbish.
Example Sentences:
(1) Sally’s transformation from snobby busybody to the knicker factory’s answer to Hillary Clinton is now complete and she always has one eye on boosting her political profile.
(2) Quite when the word "hipster" stopped denoting muso snobs in peculiar jeans and instead started referring to people who get snobby about coffee beans and beer hops, drink cocktails out of jam jars and dress as though they are pioneers from the outback even though they actually live in Brooklyn or Homerton, I really could not say.
(3) This usually happens for snobby reasons (basically, the mother's name packs more punch).
(4) Trierweiler, too, disliked living in the Elysée, surrounded by “snobby” advisers who “feel themselves very superior” and to whom “betrayal is seen as a virtue”.
(5) Tour guide Inigo from the brilliantly informal Go Local explained that the city is often thought snobby by inhabitants of Bilbao and Victoria, its two big neighbours.
(6) All this nonsense from very snobby Tories that we should not dominate the campaign and I should go on holiday for six months – forget it!
(7) Well handled.” Trump was later to claim that he found the presidential attention flattering, but a follow-up roast by the night’s professional comedian Seth Meyers rankled visibly and arguably set the tone for an 2016 election cycle driven by hatred of a snobby metropolitan elite holding its nose at America.
(8) Part-time professional skateboarder Jon Tolley and DJ Mike Smith became its owners, keen to change the snobbiness that surrounded record store culture – as other local businesses folded around them.
(9) José Ignacio may be low key and discreet, but it's relentlessly and shamelessly snobby.
(10) In that way, I would say that being smart or cynical or knowing or any of the things that I might think about myself in a snobby way and think Victoria Beck- ham isn't - are entirely useless.
(11) "At the time, I was a bit snobby about those kind of shows," he admits.
(12) Another piece of Heseltine folklore is a fabulously snobby comment recorded by the late political diarist Alan Clark: "The trouble with Michael is that he had to buy his own furniture."
(13) I know that sounds snobby – maybe it is – but we've been to university, we've both worked our backsides off, and we're not seeming to get the rewards for it.
(14) The snobby tone of the coverage, in fact, was much like the underlying spirit of the episode itself.
(15) For decades, the famously snobby Baron Michael Jopling lorded it over Westmorland – he was the aristocrat who once dismissed the then deputy prime minister Michael Heseltine, an upwardly mobile commoner, by saying: “The trouble with Michael is that he had to buy all his furniture.” Currently, Rory Stewart, ex-governor of two Iraq provinces, is installed in a cottage in Penrith and the Borders for the Conservatives, and down in the South Lakes the irrepressible Tim Farron, president of the Lib Dems, is putting a brave face on it all.
(16) To call out voters for falling for such damagingly racist and sexist messages is viewed by politicians as a vote-killer and dangerously snobby by the media, as though working-class people are precious toddlers who must be humoured and can’t possibly be held responsible for any flawed thinking.
(17) Therefore his supporters say that all criticism of him comes from a snobby media.
(18) He changed American attitudes – there are those who say he made Americans almost as snobby as the British or Europeans.” McDowell says he does not know if he agrees, “but certainly he has been an immense force”.
(19) Which is why, again – back to X Factor – why there is that slightly manic quality about those kids, and again why I'm sympathetic when people are so snobby about them.
(20) "There wasn't any snobbiness, like: 'That's not a real score.'