What's the difference between known and novel?

Known


Definition:

  • (p. p.) of Know
  • (p. p.) of Know.

Example Sentences:

  • (1) National policy on the longer-term future of the services will not be known until the government publishes a national music plan later this term.
  • (2) Until his return to Brazil in 1985, Niemeyer worked in Israel, France and north Africa, designing among other buildings the University of Haifa on Mount Carmel; the campus of Constantine University in Algeria (now known as Mentouri University); the offices of the French Communist party and their newspaper l'Humanité in Paris; and the ministry of external relations and the cathedral in Brasilia.
  • (3) Low birth weight, short stature, and mental retardation were common features in the four known patients with r(8).
  • (4) Ethanol and L-ethionine induce acute steatosis without necrosis, whereas azaserine, carbon tetrachloride, and D-galactosamine are known to produce steatosis with varying degrees of hepatic necrosis.
  • (5) Although measurements are easily obtained with a tape measure, the validity of these measurements is not known.
  • (6) From these data it is possible to predict theoretically the apparent temperature difference as seen by an infrared scanner or radiometer with a detector of which the spectral detectivity, D (lambda), is known.
  • (7) They broke in with a battering ram: an armoured vehicle known as a Bearcat.
  • (8) Infection with opportunistic organisms, either singly or in combination, is known to occur in immunocompromised patients.
  • (9) Finally the advanced automation of the equipment allowed weekly the evaluation of catecholamines and the whole range of their known metabolites in 36 urine samples.
  • (10) PBOP was as effective as polymyxin B nonapeptide (PMBN), the known very potent permeabilizer.
  • (11) Angle closure glaucoma is a well-known complication of scleral buckling and it is of particular interest when it occurs in eyes with previously normal angles.
  • (12) It is a place that occupies two thirds of our planet but very little is known of vast swaths of it.
  • (13) It has 61% homology with tRNA(Leu)(anticodon m5CAA) and 63% homology with tRNA(Leu)(anticodon UAG), the two other known yeast tRNAs(Leu).
  • (14) The mtRF-1 could translate all of the known termination codons in the rat mitochondrial genome.
  • (15) Groups of inbred female mice of strains CBA or C3H were infected genitally with a pathogenic human strain of Chlamydia trachomatis (N.I.1, serovar F) known to produce salpingitis and infertility in mice.
  • (16) To become president of Afghanistan , Ashraf Ghani Ahmadzai changed his wardrobe and modified his name, gave up coffee, embraced a man he once denounced as a “known killer” and even toyed with anger management classes to tame a notorious temper.
  • (17) The method used in connection with the well known autoplastic reimplantation not only presents an alternative to the traditional apicoectomy but also provides additional stabilization of the tooth by lengthing the root with cocotostabile and biocompatible A1203 ceramic.
  • (18) These results do not support the view that in the rat pheromones from adult males enhance puberty in females, contrary to what is known to happen in the mouse.
  • (19) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
  • (20) This condition may be caused by the prolonged, repetitive elevations of gonadal steroids and other hormones known to suppress gonadotropin-releasing hormone secretion that are elicited by their daily exercise.

Novel


Definition:

  • (a.) Of recent origin or introduction; not ancient; new; hence, out of the ordinary course; unusual; strange; surprising.
  • (a.) That which is new or unusual; a novelty.
  • (a.) News; fresh tidings.
  • (a.) A fictitious tale or narrative, professing to be conformed to real life; esp., one intended to exhibit the operation of the passions, and particularly of love.
  • (a.) A new or supplemental constitution. See the Note under Novel, a.

Example Sentences:

  • (1) Moreover in MIT-1, the size of the novel polypeptide was not that predicted of the precursor (44.9 kDa) but was about 39 kDa, the same size as the authentic GS gamma polypeptide in CYT-4.
  • (2) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
  • (3) A novel prostaglandin E2 analogue, CL 115347, can be administered transdermally on a long-term basis.
  • (4) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
  • (5) Experiment 3 showed that the color-induced increase in odor intensity is not due to subjects' preexperimental experience with particular color-odor combinations, because the increase occurred with novel ones.
  • (6) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
  • (7) But what they take for a witticism might very well be true; most of Ellis's novels tell more or less the same story, about the same alienated ennui, and maybe they really are nothing more than the fictionalised diaries of an unremarkably unhappy man.
  • (8) Cyclosporine is a fungal endecapeptide of novel chemical structure that causes preferential inhibition of T helper cells.
  • (9) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
  • (10) Her novels have an enduring and universal appeal and she is recognised as one of the greatest writers in English literature.
  • (11) The complex problems have been successfully managed with novel guiding catheter shapes and ultralow profile balloons.
  • (12) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
  • (13) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
  • (14) This novel coumarin derivative significantly inhibited skin tumor initiation by DMBA in SENCAR mice when given at a dose of 200 nmol, 5 min (69% inhibition) or 24 h (76% inhibition) prior to initiation.
  • (15) Using a novel method for joining DNA sequences, we have exploited this difference between the two enzymes to identify the regions of the RT that contribute to the compounds' inhibitory activities.
  • (16) It may thus represent an artifact of the labeling procedure rather than a novel basophil-derived prostaglandin.
  • (17) Endothelin-1 (ET-1) is a novel vasoconstricting and cardiotonic peptide that is synthesized by the vascular endothelium.
  • (18) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
  • (19) Pretreatment with a novel CRF antagonist, alpha-helical CRF9-41 (130.9 nmol i.t.v.
  • (20) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.