(1) The transition was characterized by a single first order rate constant (kobs,i) which was independent of enzyme concentration.
(2) Knowledge of the salt dependences of ka and of the observed equilibrium constance Kobs of the ligand-nucleic acid interaction should usually be sufficient to determine whether a screening controlled mechanism or a pre-equilibrium mechanism is suitable to describe the process.
(3) A log kobs versus pH profile for the approach to the ionization equilibrium was determined, and a mechanism consistent with the profile was postulated.
(4) In the absence of cyanide, ferrocytochrome a3 appears at a rate (kobs) of 0.016 s-1.
(5) Above 25 microM AT.H complex, an increasing dead time displacement of p-aminobenzamidine and a downward deviation of kobs from the initial linear dependence on AT.H complex concentration were found, reflecting the saturation of an intermediate Xa.AT.H complex with a KD of 200 microM and a limiting rate of Xa-AT product complex formation of 140 s-1.
(6) At pH 7.8, the apparent single rate constant for association (kobs) at 4 degrees C was 4.72 x 10(+5).M-1.min-1.
(7) Thus, under pseudo-first order conditions ([AT]o, [H]o much greater than [T]o much less than [P]o), the observed thrombin inactivation rate constant (kobs) exhibited a saturable dependence on [AT]o or [H]o when [H]o much less than KT,H, reflecting a KAT,H (0.25 microM) similar to that directly determined by equilibrium binding.
(8) The nature of the anion often has a major effect on the magnitude of the equilibrium constant (Kobs) and rate constant (kobs) of protein-DNA interactions, but a minor effect on SKobs and Skobs, which are dominated by the cation stoichiometry.
(9) The rate constant (kobs) for loss of ADP activation exhibits a nonlinear dependence on 2-BDB-TAMP concentration, suggesting a reversible binding of reagent (KR = 0.74 mM) prior to irreversible modification.
(10) The kobs max value in tissues from insulin-dependent diabetic patients was significantly greater than that in tissues from either noninsulin-dependent diabetics or nondiabetics.
(11) Reduction by lumiflavin semiquinone followed single exponential kinetics and the observed rate constant (kobs) was linearly dependent on protein concentration (k = 1.8 X 10(7) M-1s-1 heme-1).
(12) At 0.25 M-KX, the increase in Kobs for Osym is observed to be approximately 40-fold, whereas for non-operator DNA the increase in Kobs is estimated by extrapolation to be approximately 300-fold.
(13) The Kobs of this reaction reflects the difference between the observed standard free energy change (delta G-oobs) for the hydrolysis of acetylcholine and the delta G-oobs for the hydrolysis of acetyl-CoA.
(14) The observed equilibrium constants (Kobs) of the creatine kinase (EC 2.7.3.2), myokinase (EC 2.7.4.3), glucose-6-phosphatase (EC 3.1.3.9), and fructose-1,6-diphosphatase (EC 3.1.3.11) reactions have been determined at 38 degrees C, pH 7.0, ionic strength 0.25, and varying free magnesium concentrations.
(15) Stopped-flow spectrophotometry also showed that electron transfer from the Fe-protein to the MoFe-protein in states E0 and E1H occurs at the same rate (kobs.
(16) A study of kobs vs pH suggests this active-site lysine has a pKa of 8.1 and a pH-independent rate constant of inactivation of 47,700 M-1 min-1.
(17) At all temperatures, the pH strongly influenced the observed degradation rate constant (kobs) values, with rate minima observed near pH 4.
(18) Alkylation of the N-terminal half resulted in biphasic calcium release with rates (kobs 153 s-1 and 10.9 s-1 respectively) similar to those observed in intact alkylated calmodulin.
(19) At 1.2 mM 2-BDB-TAMP, kobs = 0.060 min-1 and is not affected by alpha-ketoglutarate or GTP, but is decreased to 0.020 min-1 by 5 mM NADH and to zero by 5 mM ADP.
(20) A plot of the pseudo-first order rate constant (Kobs) versus T1K concentration was linear, and values for the association (k1) and dissociation (k-1) rate constants were obtained.
Mob
Definition:
(n.) A mobcap.
(v. t.) To wrap up in, or cover with, a cowl.
(n.) The lower classes of a community; the populace, or the lowest part of it.
(n.) A throng; a rabble; esp., an unlawful or riotous assembly; a disorderly crowd.
(v. t.) To crowd about, as a mob, and attack or annoy; as, to mob a house or a person.
Example Sentences:
(1) Levinson's film, to be titled Black Mass, will be based on the New York Times bestseller Black Mass: The True Story of an Unholy Alliance Between the FBI and the Irish Mob , by Boston Globe reporters Dick Lehr and Gerard O'Neill.
(2) A s I watched Camila Batmanghelidjh being mobbed by the small crowd demonstrating about the closure of Kids Company outside Downing Street last week, it struck me that she was more like a character out of children’s book than a real person.
(3) Ellen Page is to make her directorial debut with Miss Stevens, starring Anna Faris as a teacher chaperoning a mob of high school students to a state drama competition.
(4) The Mob+ vector pME285 (10.6 kb) carries the aph gene and the Tn501-derived merRTCA genes coding for mercuric ion resistance, another good selective marker in Pseudomonas.
(5) The Ukrainian president, Oleksandr Turchynov, had given pro-Russian locals in eastern Ukraine until Monday morning to give up their arms and the buildings they had seized, but instead a pro-Russian mob took over yet another government building in Horlivka that day.
(6) Trump, embracing the spirit of the “lock her up” mob chants at his rallies, threatened: “If I win I am going to instruct my attorney general to get a special prosecutor to look into your situation – there has never been so many lies and so much deception,” he threatened.
(7) Numbness sets in.” Philip Hope-Wallace on Look Back in Anger “I must be the only playwright this century to have been pursued up a London street by an angry mob … There was an inescapable tension in the house.
(8) High among the range of issues was the media dominance of the Globo group (whose journalists were chased away from demonstrations by an irate mob), inefficient use of public funds, forced relocations linked to Olympic real estate developments, the treatment of indigenous groups, dire inequality and excessive use of force by police in favela communities.
(9) A conjugation mixture consisted of yeast Saccharomyces cerevisiae, E. coli harboring pAY101, and E. coli carrying a helper plasmid with mob and tra.
(10) The justice minister Dominic Raab said the Labour leader had promised a “kinder politics” but was now “whipping up a mob mentality”.
(11) We suggest that the contralateral projection nuclei to the MOB of the hedgehog, unusual in other mammals, and the large number of cells with axonal collaterals projecting to both hemispheres, may be a strategy in these animals to bilaterally integrate brain functions at the expense of its reduced corpus callosum.
(12) Tn5-Mob was introduced into the E. coli R1 host replicon via conjugation on membrane filters.
(13) For NP rats, a single dominant frequency component (induced wave) was present in the MOB EEG at 4-6 days of age.
(14) There is no better symbol of London’s macho financialisation than the early 21st-century surge in skyscraper construction, the lanky delinquent mob of new towers that cluster around the City, and their gangmaster, the Shard.
(15) Tn5-Mob mobilization may be useful in the study of metal resistance in bacteria, especially in strains not studied for resistance mechanisms.
(16) Republicans have for months been claiming the White House was engaged in a cover-up, downplaying the role of an al-Qaida inspired group in the attack and suggesting instead the attack was mainly the result of a demonstration by a mob against an American-produced anti-Islam film.
(17) The pars externa (PE) system of the anterior olfactory nucleus (AON) in a primate, Callithrix jacchus, was defined by its architecture and by its connection patterns with the main olfactory bulb (MOB) as revealed by tracing techniques.
(18) Much of the focus has been on a memo of talking points drawn up by the State Department and the CIA for use by Rice in television interviews, in which she blamed a mob rather than terrorists.
(19) Kagame regards Rwanda as the victim of a diplomatic lynch mob and accuses the British government of laying the groundwork by sending the BBC and Channel 4 News to file reports critical of Rwanda.
(20) As in mammalian MOB, the majority of TH-LI neurons were clustered in the periglomerular region and appeared to send their dendritic branches into glomeruli, which as a whole make an intense TH-LI band in the glomerular layer (GML).