(1) The transition was characterized by a single first order rate constant (kobs,i) which was independent of enzyme concentration.
(2) Knowledge of the salt dependences of ka and of the observed equilibrium constance Kobs of the ligand-nucleic acid interaction should usually be sufficient to determine whether a screening controlled mechanism or a pre-equilibrium mechanism is suitable to describe the process.
(3) A log kobs versus pH profile for the approach to the ionization equilibrium was determined, and a mechanism consistent with the profile was postulated.
(4) In the absence of cyanide, ferrocytochrome a3 appears at a rate (kobs) of 0.016 s-1.
(5) Above 25 microM AT.H complex, an increasing dead time displacement of p-aminobenzamidine and a downward deviation of kobs from the initial linear dependence on AT.H complex concentration were found, reflecting the saturation of an intermediate Xa.AT.H complex with a KD of 200 microM and a limiting rate of Xa-AT product complex formation of 140 s-1.
(6) At pH 7.8, the apparent single rate constant for association (kobs) at 4 degrees C was 4.72 x 10(+5).M-1.min-1.
(7) Thus, under pseudo-first order conditions ([AT]o, [H]o much greater than [T]o much less than [P]o), the observed thrombin inactivation rate constant (kobs) exhibited a saturable dependence on [AT]o or [H]o when [H]o much less than KT,H, reflecting a KAT,H (0.25 microM) similar to that directly determined by equilibrium binding.
(8) The nature of the anion often has a major effect on the magnitude of the equilibrium constant (Kobs) and rate constant (kobs) of protein-DNA interactions, but a minor effect on SKobs and Skobs, which are dominated by the cation stoichiometry.
(9) The rate constant (kobs) for loss of ADP activation exhibits a nonlinear dependence on 2-BDB-TAMP concentration, suggesting a reversible binding of reagent (KR = 0.74 mM) prior to irreversible modification.
(10) The kobs max value in tissues from insulin-dependent diabetic patients was significantly greater than that in tissues from either noninsulin-dependent diabetics or nondiabetics.
(11) Reduction by lumiflavin semiquinone followed single exponential kinetics and the observed rate constant (kobs) was linearly dependent on protein concentration (k = 1.8 X 10(7) M-1s-1 heme-1).
(12) At 0.25 M-KX, the increase in Kobs for Osym is observed to be approximately 40-fold, whereas for non-operator DNA the increase in Kobs is estimated by extrapolation to be approximately 300-fold.
(13) The Kobs of this reaction reflects the difference between the observed standard free energy change (delta G-oobs) for the hydrolysis of acetylcholine and the delta G-oobs for the hydrolysis of acetyl-CoA.
(14) The observed equilibrium constants (Kobs) of the creatine kinase (EC 2.7.3.2), myokinase (EC 2.7.4.3), glucose-6-phosphatase (EC 3.1.3.9), and fructose-1,6-diphosphatase (EC 3.1.3.11) reactions have been determined at 38 degrees C, pH 7.0, ionic strength 0.25, and varying free magnesium concentrations.
(15) Stopped-flow spectrophotometry also showed that electron transfer from the Fe-protein to the MoFe-protein in states E0 and E1H occurs at the same rate (kobs.
(16) A study of kobs vs pH suggests this active-site lysine has a pKa of 8.1 and a pH-independent rate constant of inactivation of 47,700 M-1 min-1.
(17) At all temperatures, the pH strongly influenced the observed degradation rate constant (kobs) values, with rate minima observed near pH 4.
(18) Alkylation of the N-terminal half resulted in biphasic calcium release with rates (kobs 153 s-1 and 10.9 s-1 respectively) similar to those observed in intact alkylated calmodulin.
(19) At 1.2 mM 2-BDB-TAMP, kobs = 0.060 min-1 and is not affected by alpha-ketoglutarate or GTP, but is decreased to 0.020 min-1 by 5 mM NADH and to zero by 5 mM ADP.
(20) A plot of the pseudo-first order rate constant (Kobs) versus T1K concentration was linear, and values for the association (k1) and dissociation (k-1) rate constants were obtained.
Yob
Definition:
Example Sentences:
(1) Tory toffs repelling undesirable immigrants, providing better schools, using welfare reform as a pathway to work, clearing vandals, yobs and drunks from the streets and standing up to our masters in Brussels would be very popular, and the word would soon be forgotten.
(2) Hailed by Duncan Smith and rightwing London as the incentive that would propel the unemployed into work, universal credit has become Whitehall's equivalent of a layabout yob: nothing can make it work.
(3) Reproductive history, as reported from a validated postal questionnaire, was obtained from 204 women with scleroderma [mean year of birth (yob) 1942] and compared to that reported by 233 women with primary Raynaud's phenomenon (mean yob 1948) and 189 healthy women from a population register (mean yob 1950).
(4) I also think Anzacs were racist yobs and Anzac Day is a death cult.
(5) The distinctive check, which dates back to the 1920s, had also become uniform of choice for yobs and football hooligans.
(6) What happened to such worn-out old tropes as feral youth, yob culture, and the prime minister's own golden oldie, broken Britain?
(7) It comes to something when a documentary series featuring yobs, truants, swearing at teachers, swearing by teachers, cyber-bullying and teenage pregnancy makes you believe in the education system again.
(8) I hope the FIA are considering the implications of this fully and that events in Bahrain are not seen as they are often sold, as a bunch of yobs throwing Molotov cocktails, because that's a gross simplification.
(9) Yob, who guided delegate strategy for Rand Paul’s failed presidential campaign this year and is also the author of Campaign Chaos , a book on a potential contested convention, told the Guardian that one of the key tells for a successful delegate effort was “how effective campaigns are at keeping Sinos from being elected”.
(10) Other nations think we are yobs who go over there to drink and fight, but that's only the few who spoil it for the rest.
(11) Ed Miliband , the Labour leader, accused the prime minister of "total double standards", during prime minister's questions, saying he would be the first to back police for locking up a "yob" who swore at officers, but is refusing to sack his chief whip for the same conduct.
(12) Pointing to Mitchell, who sat near Cameron on the government front bench, Miliband said that if a "yob in a city centre" had abused and ranted at an officer in the way Mitchell had done, "the chances are they would be arrested and placed in the back of a police van — and rightly so.
(13) But while it's a night in the cell for the yob, it's a night at the Carlton Club for the chief whip.
(14) But the suspicion lurks that, just as McEnroe seems to have been contractually obliged to have an outburst or two on the veterans’ tour, so the youthful Kyrgios could easily be groomed for a perceived yob-shaped hole in the branding market.
(15) It's a very modern solution to a very old problem, for in towns and cities up and down the land, yobs have long claimed the right to cause drunken mayhem in shops and restaurants run by visible minorities.
(16) When you look back in history, highly contested conventions tended to be a disadvantage to the party that had them,” Yob said – although he noted there were exceptions, the most recent being Franklin Delano Roosevelt’s White House victory after a multi-ballot convention in 1932.
(17) Campaigns have to take care to not just make the ballot in every state but to fill their slates of delegates with names and ensure that those delegates pledged to them are actual supporters and not what veteran Republican strategist John Yob calls “supporters in name only”, or Sinos.
(18) As Yob noted, delegations such as those from Guam, American Samoa and the Virgin Islands (where he is standing to be a delegate) will play a crucial role as a result.
(19) She’d claimed that I was drunk and disorderly and throwing food around like some yob,” Coe recalled.
(20) Behind the far-left yobs, who disgrace every good cause in Britain, the protesters who did not riot in Parliament Square on Thursday looked almost pitiable.