(1) Previous attempts to purify this enzyme from the liquid endosperm of kernels of Zea mays (sweet corn) were not entirely successful owing to the lability of partially purified preparations during column chromatography.
(2) EDRF is even more labile than prostacyclin, with a half-life of about 6 seconds, and it has recently been identified as nitric oxide.
(3) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(4) Bile flow was stimulated significantly by VPA and MCCA, but not by CCA; changes in bile flow correlated with the biliary excretion rate of base-labile conjugates rather than with excretion of the parent compounds themselves.
(5) Binding activity was labile to heat, and to treatment with pepsin or trypsin.
(6) The following factors were studied: relative ability to adsorb virus, sedimentation of the adsorbing components, heat lability of the components, virus elution, and recovery of cell-associated virus.
(7) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(8) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(9) Detailed studies of the effects of acid pH on the formation of Fraction C after borohydride reduction demonstrated the apparent lability of the non-reduced form, thus confirming our previous findings (Bailey & Lister, 1968).
(10) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(11) In 13 (26%) inpatients and 11 (49%) outpatients Shigella was found, and heat-labile and heat-stable forms of enterotoxigenic Escherichia coli were found in 9 (18%) inpatients and 1 (4%) outpatient.
(12) The factor appears to rearrange the distribution of myotube AcCho receptors either by aggregating mobile AcCho receptors or by stabilizing labile receptor aggregates.
(13) The transformation-related protein p53 is normally very labile.
(14) The results are consistent with an action of banana tree juice on the molecule responsible for excitation-contraction coupling in skeletal muscle, resulting in a labilization of intracellular Ca2+.
(15) It was determined by mouse protection tests that the specificity of protective antibodies was directed toward a trypsin labile antigen.
(16) Twelve days following discontinuation of the drug, the patient continued to experience diarrhea, restlessness, emotional lability, and anxiety.
(17) Cytokine secretion by activated lymphocytes or mast cells is preceded by dramatic stabilization of the normally labile GM-CSF mRNA.
(18) (i) The secretions of most of the deep cells and the majority of superficial cells contained sialidase-labile and sialidase-resistant sialomucins.
(19) The studies reported here demonstrate the presence of heat-labile serum factors in normal human sera which killed B. fragilis directly and which promote its phagocytosis and killing by PMNs.
(20) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
Lapse
Definition:
(v. i.) To become ineffectual or void; to fall.
(v. i.) To fall or pass from one proprietor to another, or from the original destination, by the omission, negligence, or failure of some one, as a patron, a legatee, etc.
(n.) A gliding, slipping, or gradual falling; an unobserved or imperceptible progress or passing away,; -- restricted usually to immaterial things, or to figurative uses.
(n.) A slip; an error; a fault; a failing in duty; a slight deviation from truth or rectitude.
(n.) The termination of a right or privilege through neglect to exercise it within the limited time, or through failure of some contingency; hence, the devolution of a right or privilege.
(n.) A fall or apostasy.
(v. i.) To pass slowly and smoothly downward, backward, or away; to slip downward, backward, or away; to glide; -- mostly restricted to figurative uses.
(v. i.) To slide or slip in moral conduct; to fail in duty; to fall from virtue; to deviate from rectitude; to commit a fault by inadvertence or mistake.
(v. t.) To let slip; to permit to devolve on another; to allow to pass.
(v. t.) To surprise in a fault or error; hence, to surprise or catch, as an offender.
Example Sentences:
(1) We had a brief conversation and I said to him he was acting from high honour here, and I said how sorry I was this wasn’t happening in three or four years time..because Barry is a man of honour..and I think he is a very capable premier and I think he has been missed.” Asked whether he had ever met Nick di Girolamo , the prime minister said both he and Mr di Girolamo attended a lot of functions, and “I don’t for a moment say I have never met him but I don’t recall it.” But former federal Liberal MP Ross Cameron sounded much more sceptical about O’Farrell’s memory lapse when speaking to Sky News.
(2) The duration and severity of the pulmonary abscess, the method of surgical treatment, the lapse of time after the operation, the course of the restorative processes, complications and concomitant diseases, the degree or respiratory and circulatory insufficiency, the patients' age, profession, and the conditions and character of work are taken into account during examination.
(3) In nine patients there was a temporary lapse of supervision.
(4) If REpower had waited until it had secured planning permission for the windfarms before it began building the turbine factory, permission would have lapsed before it had had time to supply the turbines.
(5) He cited the occurrence in 2011–12 of 326 "never events" – serious safety lapses that should never occur in the NHS, such as surgeons operating on the wrong part of a patient's body – as further proof that the NHS's safety culture was inadequate.
(6) Increases in mutant frequency were clearly induced by all eight chemicals, the magnitudes of which were dependent on the chemical, dose, method of dosing, tissue analyzed, and the time lapse between treatment and isolation of DNA.
(7) We report observations from time-lapse films of the development of Dictyostelium discoideum (Dd) stained with the vital dye neutral red.
(8) (c) In patients with MR and postoperative heart failure, there was a tendency for EF to decrease after a lapse of one month postoperatively.
(9) Analysis by time-lapse video microscopy indicates that two processes produce the fibers.
(10) In view of the prolonged lapse of time between the initial endocrine manifestations and the eventual diagnosis, even though no cause is apparent in the other three patients, it is suggested that close follow-up be carried out to rule out such a possibility in patients with this endocrine-radiological entity.
(11) Quantitative time-lapse videomicroscopy showed that the CT-induced retraction of osteoclasts also involved activation of the PKC pathway and could therefore be induced by phorbol esters.
(12) It’s just been a catalogue of disasters – the late nomination, when his party membership lapsed , the [alleged] punch-up.
(13) Time-lapse cinemicrography reveals that in clone B ZR-75-1 cells, which are not sensitive to the DNA synthesis-inhibitory effect of IL-6 or to its cell-separating effect on preformed colonies, IL-6 can still block rapid readherence of post-mitotic cells to their neighbors and to the substratum leading to enhanced dispersal of cancer cells into the culture medium.
(14) A vertebral occlusion or dissection is a problem of considerable complexity, requiring individualized management depending on the patient's symptomatology, location and nature of the injury, and time lapsed since the injury.
(15) On the day I arrive a time lapse of cloud is drifting across the ridge, above a geometry of Inca stairways and terraces cut into a steep, jungly spur above the Apurímac river, 100 miles west of Cusco in southern Peru.
(16) We have used fluorescence analogue cytochemistry in conjunction with time lapse recording to study the dynamics of alpha-actinin, a major component of the Z line, during myofibrillogenesis.
(17) Measurements of the soluble TNF receptor (sTNF-R) concentrations in healthy individuals at time lapses of 3 months (17 individuals) or 1 year (51 individuals) showed a significant correlation between the first and the second measurements from each individual, implying that individual differences are stable.
(18) The dynamic nature of Chlamydia trachomatis inclusions was studied by video and 35 mm time-lapse photomicrography of live cells, and by immunolocalization of inclusions in fixed cells.
(19) The authors report on the frequency of family congenital heart disease in a consecutive series of 380 congenital patients, studied in the lapse of one year in the Pediatric Cardiology Service of the National Institute of Cardiology of Mexico.
(20) A time lapse cinemicrographic study shows that, at low concentrations, nicotine can speed up cytokinesis and, at high concentrations, prolong the duration of metaphase in HeLa cells.