(1) Previous attempts to purify this enzyme from the liquid endosperm of kernels of Zea mays (sweet corn) were not entirely successful owing to the lability of partially purified preparations during column chromatography.
(2) EDRF is even more labile than prostacyclin, with a half-life of about 6 seconds, and it has recently been identified as nitric oxide.
(3) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(4) Bile flow was stimulated significantly by VPA and MCCA, but not by CCA; changes in bile flow correlated with the biliary excretion rate of base-labile conjugates rather than with excretion of the parent compounds themselves.
(5) Binding activity was labile to heat, and to treatment with pepsin or trypsin.
(6) The following factors were studied: relative ability to adsorb virus, sedimentation of the adsorbing components, heat lability of the components, virus elution, and recovery of cell-associated virus.
(7) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(8) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(9) Detailed studies of the effects of acid pH on the formation of Fraction C after borohydride reduction demonstrated the apparent lability of the non-reduced form, thus confirming our previous findings (Bailey & Lister, 1968).
(10) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(11) In 13 (26%) inpatients and 11 (49%) outpatients Shigella was found, and heat-labile and heat-stable forms of enterotoxigenic Escherichia coli were found in 9 (18%) inpatients and 1 (4%) outpatient.
(12) The factor appears to rearrange the distribution of myotube AcCho receptors either by aggregating mobile AcCho receptors or by stabilizing labile receptor aggregates.
(13) The transformation-related protein p53 is normally very labile.
(14) The results are consistent with an action of banana tree juice on the molecule responsible for excitation-contraction coupling in skeletal muscle, resulting in a labilization of intracellular Ca2+.
(15) It was determined by mouse protection tests that the specificity of protective antibodies was directed toward a trypsin labile antigen.
(16) Twelve days following discontinuation of the drug, the patient continued to experience diarrhea, restlessness, emotional lability, and anxiety.
(17) Cytokine secretion by activated lymphocytes or mast cells is preceded by dramatic stabilization of the normally labile GM-CSF mRNA.
(18) (i) The secretions of most of the deep cells and the majority of superficial cells contained sialidase-labile and sialidase-resistant sialomucins.
(19) The studies reported here demonstrate the presence of heat-labile serum factors in normal human sera which killed B. fragilis directly and which promote its phagocytosis and killing by PMNs.
(20) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
Stubborn
Definition:
(a.) Firm as a stub or stump; stiff; unbending; unyielding; persistent; hence, unreasonably obstinate in will or opinion; not yielding to reason or persuasion; refractory; harsh; -- said of persons and things; as, stubborn wills; stubborn ore; a stubborn oak; as stubborn as a mule.
Example Sentences:
(1) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
(2) Of course there are some who are stubborn, like Robert Mugabe.
(3) The prime minister insisted, however, that he and other world leaders were not being stubborn over demands that the Syrian leader, President Bashar al-Assad, step down at the end of the peace process.
(4) It’s clear their relationship is most similar to that of a stubborn son and his long suffering mother.
(5) The contrast between these two worlds – one legal and flourishing, the other illegal and stubbornly disregarding of state lines – can seem baffling, yet it may have profound consequences for whether this unique experiment spreads.
(6) The causes of failure after acute injury include extensive local soft tissue and bony damage, severe concomitant head, chest or abdominal wounding, stubborn reliance on negative arteriograms in patients with probable arterial injury, failure to repair simultaneous venous injuries, or harvesting of a vein graft from a severely damaged extremity.
(7) "It was the character of David Cameron – his stubbornness, his anger and his rush towards war – which was the central cause of his defeat on Thursday night."
(8) Rebus, promised the Scottish author, will be "as stubborn and anarchic as ever", and will find himself in trouble with the author's latest creation, Malcolm Fox, of Edinburgh's internal affairs unit.
(9) A rising jobless total and an unemployment rate sticking at a stubbornly high 8% overshadowed a better than expected 27,100 fall in the claimant count in April, which compared with analysts' forecasts for a 20,000 drop.
(10) But the part of me that resists that, that is stubborn and wants to bulldoze things, gets in my way.
(11) One is the stubborn mystery of how a giant of its liberation movements, an intellectual who showed forgiveness and magnanimity years before Mandela emerged from jail, could turn into the living caricature of despotism.
(12) Sanctioning is no longer a last resort tactic aimed at the stubbornly workshy, say critics, but a crude way of pushing down claimant numbers and cutting back on the benefits bill.
(13) He was only 29 at the time, but nevertheless had that kind of stubborn certainty.
(14) They have a sort of stubbornness.” He later deals with hecklers at a Fifa HQ press event : “Listen, gentlemen, we are not in a bazaar .
(15) Dombrovskis stubbornly refused, instead pursuing "internal devaluation", depressing wages and conducting what he says was a 17% fiscal adjustment programme (the IMF says 15%).
(16) They formed a stubborn line in front of Wojciech Szczesny’s goal even if the statistics showed Arsenal’s pass-completion rate went down from 89% in the first half to 66% in the second.
(17) This was the first time a grouping of BME senior managers crossing health and social care had met together to look at barriers to gaining top jobs, and ways of breaking through systems which stubbornly never seem to shift.
(18) Broadly defined, this sort of behaviour involves procrastination, stubbornness, resentment, sullenness, obstructionism, self-pity and a tendency to create chaotic situations.
(19) At which point – obviously – you reach the stubborn limits of the debate: from even the most supposedly imaginative Labour people as much as any Tories, such heresies would presumably be greeted with sneering derision.
(20) A stubborn negativity characterised the insurrection.