(1) Previous attempts to purify this enzyme from the liquid endosperm of kernels of Zea mays (sweet corn) were not entirely successful owing to the lability of partially purified preparations during column chromatography.
(2) EDRF is even more labile than prostacyclin, with a half-life of about 6 seconds, and it has recently been identified as nitric oxide.
(3) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(4) Bile flow was stimulated significantly by VPA and MCCA, but not by CCA; changes in bile flow correlated with the biliary excretion rate of base-labile conjugates rather than with excretion of the parent compounds themselves.
(5) Binding activity was labile to heat, and to treatment with pepsin or trypsin.
(6) The following factors were studied: relative ability to adsorb virus, sedimentation of the adsorbing components, heat lability of the components, virus elution, and recovery of cell-associated virus.
(7) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(8) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(9) Detailed studies of the effects of acid pH on the formation of Fraction C after borohydride reduction demonstrated the apparent lability of the non-reduced form, thus confirming our previous findings (Bailey & Lister, 1968).
(10) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(11) In 13 (26%) inpatients and 11 (49%) outpatients Shigella was found, and heat-labile and heat-stable forms of enterotoxigenic Escherichia coli were found in 9 (18%) inpatients and 1 (4%) outpatient.
(12) The factor appears to rearrange the distribution of myotube AcCho receptors either by aggregating mobile AcCho receptors or by stabilizing labile receptor aggregates.
(13) The transformation-related protein p53 is normally very labile.
(14) The results are consistent with an action of banana tree juice on the molecule responsible for excitation-contraction coupling in skeletal muscle, resulting in a labilization of intracellular Ca2+.
(15) It was determined by mouse protection tests that the specificity of protective antibodies was directed toward a trypsin labile antigen.
(16) Twelve days following discontinuation of the drug, the patient continued to experience diarrhea, restlessness, emotional lability, and anxiety.
(17) Cytokine secretion by activated lymphocytes or mast cells is preceded by dramatic stabilization of the normally labile GM-CSF mRNA.
(18) (i) The secretions of most of the deep cells and the majority of superficial cells contained sialidase-labile and sialidase-resistant sialomucins.
(19) The studies reported here demonstrate the presence of heat-labile serum factors in normal human sera which killed B. fragilis directly and which promote its phagocytosis and killing by PMNs.
(20) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.
Liability
Definition:
(n.) The state of being liable; as, the liability of an insurer; liability to accidents; liability to the law.
(n.) That which one is under obligation to pay, or for which one is liable.
(n.) the sum of one's pecuniary obligations; -- opposed to assets.
Example Sentences:
(1) Liability of retransplanted syngeneic skin grafts to rejection could be almost entirely abolished by their exposure to 300 rads irradiation before placement on the intermediate host.
(2) Tata Steel, the owner of Britain’s largest steel works in Port Talbot, is in talks with the government about a similar restructuring for the British Steel pension scheme , which has liabilities of £15bn.
(3) These results are discussed in relation to previous reports suggesting a common addiction liability for both morphine and alcohol in inbred strains of animals.
(4) The precise aetiology of AHQS is still unresolved but it is concluded that it probably occurs post-natally and that some pigs have a genetic liability to develop the condition.
(5) But Burr admitted the bill would still allow companies to share directly with the NSA, and could potentially receive liability protections if information is shared “not electronically”.
(6) Two years later, the Guardian could point to reforms that owed much to what Ashley called his "bloody-mindedness" in five areas: non-disclosure of victims' names in rape cases; the rights of battered wives; the ending of fuel disconnections for elderly people; a royal commission on the legal profession; and civil liability for damages such as those due to thalidomide victims.
(7) For a substantial majority of the symptoms, the variance in liability was best explained by only genetic factors and environmental influences specific to the individual, where 33% to 46% of the variance was due to genetic factors.
(8) The authors describe several recent court cases in which judges have ignored or distorted acceptable clinical practices, conceivably creating a new liability standard whereby a tragic outcome is considered the result of failure to apply appropriate judgment.
(9) Whilst a charity may seem to have plenty of cash to meet its general liabilities, if the money is in the form of restricted funds it can only be used with permission of the donor or the Charity Commission .
(10) The Tony Abbott lecturing the American president on taxation fairness is, of course, the one who as Australian prime minister is presiding over policies of taxation amnesty for the richest Australians who have themselves offshored their hidden wealth, capping their taxable liability to merely the last four years.
(11) Recent court decisions since the landmark Wickline v. The State of California case in 1987 have addressed this issue of shared liability between payors and providers.
(12) We could be in a situation now where the potential liabilities are higher, which makes it more unlikely to find private investment.
(13) In summary, there are now available very potent narcotics, with small side effect liability.
(14) Continued escalation of claims frequency, however, and average paid-claim costs mean that other remedies will have to be sought if the professional liability problem is to be solved.
(15) But once legal liability cases began, evidence emerged from internal documents that Wyeth knew of far more cases of pulmonary hypertension than had been declared either to the FDA or to patients.
(16) In summary, the liability to exencephaly in SELH mice appears to be a multifactorial threshold trait, and it therefore resembles human neural tube defects in type of genetic etiology.
(17) This escape from liability occurs despite the fact that almost half of all traffic fatalities are attributable to alcohol.
(18) The infrastructure of New York that was once an "engineering marvel" is now a "liability", he said, urging a long-term rethink.
(19) To assess the physical dependence liability of dynorphin A analogs, mice were given repeated injections of various dynorphin A analogs twice daily for 5 days, and rats were given repeated administration of [N-methyl-Tyr1,N-methyl-Arg7,D-Leu8]dynorphin-A-(1-8) ethylamide (E-2078) twice daily for up to 7 weeks.
(20) The relative merits and liabilities for each wavelength and delivery system are discussed.