(a.) Requiring labor, perseverance, or sacrifices; toilsome; tiresome.
(a.) Devoted to labor; diligent; industrious; as, a laborious mechanic.
Example Sentences:
(1) The quantitative method used for determination of HBDH is reliable, accurate, simple and rapid and therefore has better value in a clinical setting than electrophoresis and adsorption techniques which are laborious and time consuming.
(2) Conventional procedures for the isolation of uncontaminated polysomal RNAs which rely on sucrose density centrifugations are laborious and unsuitable for large scale isolations.
(3) While the TLC assay is accurate and sensitive, it is laborious.
(4) The aim of the present study was to develop a method which allows determination of pseudo (PsChE) and acetyl cholinesterase (AChE) activities in single hemolyzed blood samples of workers exposed to cholinesterase-inhibiting compounds, avoiding the time-consuming and laborious separation of plasma and erythrocytes.
(5) TR-FIA has several advantages over the more laborious techniques available so far: (i) high sensitivity, (ii) large assay ranges, (iii) rapidity and large number of simultaneous assays, (iv) simplicity, and (v) low cost provided that the laboratory has equipment for time-resolved fluorometry.
(6) The collection of blood monocytes is much less laborious than the sampling of AMs.
(7) Winston Churchill, when he was offered the role of minister of the local government board in 1906, commented: "There is no place more laborious, more anxious, more thankless, more cloaked with petty and even squalid detail, more full of hopeless and insoluble difficulties."
(8) The procedure needs half the amount of reagents as separate determination of each of the two mycotoxin, and is far less laborious.
(9) Patient charts allow the capture of all information relevant to the patient, but are laborious to review in detail.
(10) HLA typing of amniotic cells for clinical purposes using the conventional cytotoxicity assay is a laborious and complicated procedure.
(11) Current methods for determining plasma prekallikrein, one of three zymogens of the contact phase of plasma proteolysis, are laborious and impractical for general use in a clinical laboratory.
(12) The method used in the present study is less laborious than morphometry employing electron microscopy.
(13) At present rhinoviruses are detected and serotyped in tissue cultures, a slow and laborious process.
(14) Both procedures detect tubular damage equally well and neither requires laborious sample treatment.
(15) Providers of HHC services are burdened by the laborious process of obtaining favorable coverage determinations for short-term-care patients when home care substitutes for institutional care.
(16) Yet, comparison of three-dimensional structures is a laborious time-consuming procedure that typically requires a manual phase.
(17) The core variable that emerged from the data was labeled "constructing a personal residence" to reflect the participants' descriptions of their experiences as laborious, active and constructive.
(18) Only four of those cleared have actually left Guantánamo, owing to internal bureaucracy and laborious diplomacy.
(19) This method was much less laborious than other methods that have been used so far, and most significantly, constant results were obtained in repeated experiments.
(20) The resulting Kd and maximum binding site values with 36 tumor tissue samples approximated the values obtained with the more laborious, larger tissue sample-demanding six-point Scatchard plot.
Painful
Definition:
(a.) Full of pain; causing uneasiness or distress, either physical or mental; afflictive; disquieting; distressing.
(a.) Requiring labor or toil; difficult; executed with laborious effort; as a painful service; a painful march.
(a.) Painstaking; careful; industrious.
Example Sentences:
(1) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(2) All subjects completed the Coping Strategies Questionnaire, which measures the use and perceived effectiveness of a variety of cognitive and behavioral coping strategies in controlling and decreasing pain.
(3) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(4) Sixteen patients were operated on for lumbar pain and pain radiating into the sciatic nerve distribution.
(5) Needle acupuncture did, however, increase the pain threshold compared with the initial value (alpha = 0.1%).
(6) Pain is not reported in the removal area, the clinical examinations show identical findings on both patellar tendons, X-ray and ultrasound evaluations do not demonstrate any change in patellar position.
(7) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(8) However, as the plan unravels, Professor Marcus's team turn on one another, with painfully (if painfully funny) results.
(9) During the chronic phase, pain was assessed using visual analogue scales at 8 AM and 4 PM daily.
(10) Symptoms, particularly colicky abdominal pain, improved during the period of chelation therapy.
(11) Cook, who has postbox-red hair and a painful-looking piercing in his lower lip, was now on stage in discussion with four fellow YouTubers, all in their early 20s.
(12) The main clinical symptom was pain, usually sciatica, while neurological symptoms were less common than they are in adults.
(13) The study revealed that hypophysectomy and ventricular injection of AVP dose dependently raised pain threshold and these effects were inhibited by naloxone.
(14) Anxious mood and other symptoms of anxiety were commonly seen in patients with chronic low back pain.
(15) During these delays, medical staff attempt to manage these often complex and painful conditions with ad hoc and temporizing measures,” write the doctors.
(16) In this study, a potassium nitrate-polycarboxylate cement was used as a liner and was found clinically to tend to preserve pulpal vitality and significantly eliminate or decrease postoperative pain.
(17) The successful treatment of the painful neuroma remains an elusive surgical goal.
(18) Univariate and multivariate analyses indicated previous LBP or back pain in another location of the spine were strongly associated with LBP during the study year.
(19) Our previous study demonstrated that acupuncture increased pain threshold of the body, especially in the inflammatory area.
(20) The triad of epigastric pain unrelieved by antacids, bilious vomiting, and weight loss, particularly after a gastric operation should make one suspect this syndrome.