(a.) Requiring labor, perseverance, or sacrifices; toilsome; tiresome.
(a.) Devoted to labor; diligent; industrious; as, a laborious mechanic.
Example Sentences:
(1) The quantitative method used for determination of HBDH is reliable, accurate, simple and rapid and therefore has better value in a clinical setting than electrophoresis and adsorption techniques which are laborious and time consuming.
(2) Conventional procedures for the isolation of uncontaminated polysomal RNAs which rely on sucrose density centrifugations are laborious and unsuitable for large scale isolations.
(3) While the TLC assay is accurate and sensitive, it is laborious.
(4) The aim of the present study was to develop a method which allows determination of pseudo (PsChE) and acetyl cholinesterase (AChE) activities in single hemolyzed blood samples of workers exposed to cholinesterase-inhibiting compounds, avoiding the time-consuming and laborious separation of plasma and erythrocytes.
(5) TR-FIA has several advantages over the more laborious techniques available so far: (i) high sensitivity, (ii) large assay ranges, (iii) rapidity and large number of simultaneous assays, (iv) simplicity, and (v) low cost provided that the laboratory has equipment for time-resolved fluorometry.
(6) The collection of blood monocytes is much less laborious than the sampling of AMs.
(7) Winston Churchill, when he was offered the role of minister of the local government board in 1906, commented: "There is no place more laborious, more anxious, more thankless, more cloaked with petty and even squalid detail, more full of hopeless and insoluble difficulties."
(8) The procedure needs half the amount of reagents as separate determination of each of the two mycotoxin, and is far less laborious.
(9) Patient charts allow the capture of all information relevant to the patient, but are laborious to review in detail.
(10) HLA typing of amniotic cells for clinical purposes using the conventional cytotoxicity assay is a laborious and complicated procedure.
(11) Current methods for determining plasma prekallikrein, one of three zymogens of the contact phase of plasma proteolysis, are laborious and impractical for general use in a clinical laboratory.
(12) The method used in the present study is less laborious than morphometry employing electron microscopy.
(13) At present rhinoviruses are detected and serotyped in tissue cultures, a slow and laborious process.
(14) Both procedures detect tubular damage equally well and neither requires laborious sample treatment.
(15) Providers of HHC services are burdened by the laborious process of obtaining favorable coverage determinations for short-term-care patients when home care substitutes for institutional care.
(16) Yet, comparison of three-dimensional structures is a laborious time-consuming procedure that typically requires a manual phase.
(17) The core variable that emerged from the data was labeled "constructing a personal residence" to reflect the participants' descriptions of their experiences as laborious, active and constructive.
(18) Only four of those cleared have actually left Guantánamo, owing to internal bureaucracy and laborious diplomacy.
(19) This method was much less laborious than other methods that have been used so far, and most significantly, constant results were obtained in repeated experiments.
(20) The resulting Kd and maximum binding site values with 36 tumor tissue samples approximated the values obtained with the more laborious, larger tissue sample-demanding six-point Scatchard plot.
Uphill
Definition:
(adv.) Upwards on, or as on, a hillside; as, to walk uphill.
(a.) Ascending; going up; as, an uphill road.
(a.) Attended with labor; difficult; as, uphill work.
Example Sentences:
(1) Distance running performance is slower on hilly race courses than flat courses even when the start and finish are at the same elevation, resulting in equal amounts of uphill and downhill running.
(2) Gillard faces an uphill battle convincing the electorate to back her.
(3) Like the parental strain, all three types of triple mutant showed moderate rates of downhill lactose transport and were defective in the uphill accumulation of sugars.
(4) The ascorbate oxidation was coupled to the uphill Na+ extrusion which was stimulated by CCCP and a penetrating weak base, diethylamine, as well as by valinomycin with or without diethylamine.
(5) Physiological strain was greater in uphill than in level or downhill walking (P less than .001).
(6) Senator Davis is a strong, viable, credible candidate who has raised a substantial amount of money and is the best candidate for Democrats – but it’s still an uphill battle,” he said.
(7) These results indicate that body posture can affect energy expenditure during uphill bicycling through factors unrelated to air resistance.
(8) It functions as a pair of easy-to-use skis for walking uphill, then when it’s time to head down, it quickly transforms into a toboggan for riding safely and enjoyably back to the resort, perhaps even with a few powder turns along the way.
(9) Speaking to the Guardian, Rotheram acknowledged the party faced an uphill struggle in a campaign the Tories are framing as a personality contest between party leaders.
(10) Stonewall does great work but the gay campaign for marriage equality faced an uphill struggle, which was made worse by Stonewall constantly undermining our efforts.
(11) It's going to be uphill for LA here - New York should be thinking: "No stupid penalties, no stupid penalties..." and repeat.
(12) As the transport of cefaclor showed no uphill uptake in the presence of a H+ gradient and its H+ stimulated uptake was small, a H+ gradient-independent carrier-mediated system seems to participate in its transport.
(13) The post-trial injection of 1 ng SP (in 0.5 microliter volume) led to significantly longer latencies in the uphill response.
(14) These are our treaty lands, and we need to protect clean water.’ Photograph: Sam Levin for the Guardian In a recent interview, Archambault acknowledged that the tribes face an uphill battle in the US judicial system: “We always knew that the federal court system was against Indian country.
(15) Heart rate and skiing velocities were analyzed over a flat, an uphill, and a downhill section, as well as for the total loop.
(16) Although efforts to win over Republican hawks appear close to gaining sufficient support in the Senate, the White House continues to face an uphill struggle to persuade enough members of Congress from both parties to authorise its planned strike against Syria in the House.
(17) We have a lot to do in the run up to 2020 – there’s a long road ahead of us and it will be an uphill struggle, but if we can mobilise more people, young and old, and continue to provide a real alternative to austerity and Obsornomics, we might just be in with a fighting chance.
(18) Dyspnoea grade 1 (shortness of breath when walking quickly on the level or uphill) was less well related to age.
(19) Transport of L-glutamic acid into the fission yeast Schizosaccharomyces pombe grown to the early stationary phase and preincubated for 60 min with 1% D-glucose is practically unidirectional and is mediated by a single uphill transport system with a KT of 170 microM and Jmax of 4.8 nmol min-1 (mg dry wt.)-1.
(20) It has been possible to form vesicles from the purified enzyme from Squalus acanthias and to demonstrate the ATP-dependent, ouabain inhibitable, coupled uphill transports of Na+ and K+.