(v. i.) A frame usually portable, of wood, metal, or rope, for ascent and descent, consisting of two side pieces to which are fastened cross strips or rounds forming steps.
(v. i.) That which resembles a ladder in form or use; hence, that by means of which one attains to eminence.
Example Sentences:
(1) This has been manageable, even beneficial to the economy when people slowly climbed the property ladder.
(2) Western blots of both the native alpha antigen and the cloned gene product demonstrate a regularly laddered pattern of heterogeneous polypeptides.
(3) He admitted the increased profile afforded him by appearances in movies such as Captain America , its forthcoming sequel The Winter Soldier and 2012's $1.5bn superhero ensemble piece The Avengers had helped him get a foot on the ladder as a film-maker.
(4) Methods employing electroosmotic flow in an untreated silica capillary were found to provide, at best, only partial resolution of the 23 fragments in a 1-kbp DNA ladder.
(5) Britons at the top of the social ladder are by far the most likely to have lied in order to get a job; 41% of social grade A have lied on a job application.
(6) They were thought to be caused by the rotor practice interfering with just-learned ladder skill consolidation, so that the gain in skill was not processed into long-term memory.
(7) Around the same time Clinton also beefed up President Carter's 1977 Community Reinvestment Act – forcing lenders to take a more sympathetic approach to poor borrowers trying to get on the housing ladder.
(8) When this sequence was used to probe Southern blots of EcoRI-digested genomic DNA, a ladder of bands with increments of about 170 bp was observed.
(9) Of the big national companies, the only one to take a major hit was English National Opera, while there was also a big cut for the Lowry, and complete cuts for Theatre Royal Bury St Edmunds and touring companies including the long-standing Red Ladder.
(10) On SDS-PAGE analysis, HA showed a single band at 35 kDa under reduced conditions and numerous ladder bands between 35 kDa to more than 300 kDa under nonreduced conditions.
(11) Women, in particular, have difficulty in saving sufficiently for retirement as they often take time off work to raise a family, which can set them back on the career ladder and reduce the amount they can afford to put away for pensions.
(12) "We were extremely limited as we had such a small deposit, and knew the rate of interest we would pay back would reflect this, but considered this to be short term as we were getting on the ladder.
(13) Finally, by using whole cells, it was found that the lower-molecular-weight species of the ladder pattern selectively partitioned into the hydrophobic phase of a Triton X-114 phase partitioning system, and the higher-molecular-weight bands were found in the aqueous phase.
(14) LPS-stimulated murine macrophages indicate that the "ladder" complex reflects differential glycosylation of mature 17 kDa TNF.
(15) Our advice to parents is to take full advantage of the new rules to help secure their children a place on the property ladder,” he says.
(16) Emma Reynolds MP, Labour's shadow housing minister, said: "Any help for first-time buyers struggling to get on the property ladder is welcome.
(17) The pauses observed during translation generate subsets of smaller discrete peptides, visualized in the gels as ladders of variable relative intensities, appearing exclusively and concomitantly with the fibroin.
(18) The National Association of Estate Agents said: "This announcement has added a new rung to the property ladder, one within reach of thousands of young families."
(19) The staff at the Peacocks store in Pontypridd were attempting to be as cheerful as always, laughing and joking as they clambered up a ladder to tape a new sale sign ("biggest ever – 20-70% of everything") to the window.
(20) Meanwhile, millions of other people, unable to get a foot on the property ladder, also have little choice but to rent – sometimes into their 30s or even 40s.
Sequence
Definition:
(n.) The state of being sequent; succession; order of following; arrangement.
(n.) That which follows or succeeds as an effect; sequel; consequence; result.
(n.) Simple succession, or the coming after in time, without asserting or implying causative energy; as, the reactions of chemical agents may be conceived as merely invariable sequences.
(n.) Any succession of chords (or harmonic phrase) rising or falling by the regular diatonic degrees in the same scale; a succession of similar harmonic steps.
(n.) A melodic phrase or passage successively repeated one tone higher; a rosalia.
(n.) A hymn introduced in the Mass on certain festival days, and recited or sung immediately before the gospel, and after the gradual or introit, whence the name.
(n.) Three or more cards of the same suit in immediately consecutive order of value; as, ace, king, and queen; or knave, ten, nine, and eight.
(n.) All five cards, of a hand, in consecutive order as to value, but not necessarily of the same suit; when of one suit, it is called a sequence flush.
Example Sentences:
(1) The amino acid sequence deduced from the nucleotide sequence contained both amino- and carboxyl-terminal sequences.
(2) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(3) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(4) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(5) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(6) We have examined the insertion of bovine 17 alpha-hydroxylase (P45017 alpha) into the endoplasmic reticulum of COS 1 cells to evaluate the functional role of its hydrophobic amino-terminal sequence and membrane insertion.
(7) We have investigated the increase in the spcDNA population upon cycloheximide treatment of individual sequences, which are found to amplify differentially.
(8) (dG-dA)n, but not to other homocopolymeric sequences such as (dC-dG)n .
(9) Sequence variation in the gp116 component of cytomegalovirus envelope glycoprotein B was examined in 11 clinical strains and compared with variation in gp55.
(10) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
(11) Each profile is described by a simple sequence of band transitions (BT-sequence).
(12) The complete nucleotide sequence of the gene for a cell surface protein antigen (SpaA) of Streptococcus sobrinus MT3791 (serotype g) was determined.
(13) The deduced amino acid sequence contained no consensus sequence indicative of N-glycosylation.
(14) The region containing the injection stop signal (iss) has been cloned and sequenced and found to contain numerous large repeats and inverted repeats which may be part of the iss.
(15) These sequences are also conserved in the same arrangement in minor sequence classes of minicircles from this strain.
(16) Nucleotide sequence analysis of cDNAs for asparagine synthetase (AS) of Pisum sativum has uncovered two distinct AS mRNAs (AS1 and AS2) encoding polypeptides that are highly homologous to the human AS enzyme.
(17) Based on the deduced amino acid sequence, rpL8 has a mass of 28,605 Da, a pI of 11.97, and contains 9.6% Arg and 11.9% Lys.
(18) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.
(19) A cDNA library prepared from human placenta has been screened for sequences coding for factor XIIIa, the enzymatically active subunit of the factor XIII complex that stabilizes blood clots through crosslinking of fibrin molecules.
(20) The Bohr and Root effects are absent, although specific amino acid residues, considered responsible of most of these functions, are conserved in the sequence, thus posing new questions about the molecular basis of these mechanisms.