(v. i.) A frame usually portable, of wood, metal, or rope, for ascent and descent, consisting of two side pieces to which are fastened cross strips or rounds forming steps.
(v. i.) That which resembles a ladder in form or use; hence, that by means of which one attains to eminence.
Example Sentences:
(1) This has been manageable, even beneficial to the economy when people slowly climbed the property ladder.
(2) Western blots of both the native alpha antigen and the cloned gene product demonstrate a regularly laddered pattern of heterogeneous polypeptides.
(3) He admitted the increased profile afforded him by appearances in movies such as Captain America , its forthcoming sequel The Winter Soldier and 2012's $1.5bn superhero ensemble piece The Avengers had helped him get a foot on the ladder as a film-maker.
(4) Methods employing electroosmotic flow in an untreated silica capillary were found to provide, at best, only partial resolution of the 23 fragments in a 1-kbp DNA ladder.
(5) Britons at the top of the social ladder are by far the most likely to have lied in order to get a job; 41% of social grade A have lied on a job application.
(6) They were thought to be caused by the rotor practice interfering with just-learned ladder skill consolidation, so that the gain in skill was not processed into long-term memory.
(7) Around the same time Clinton also beefed up President Carter's 1977 Community Reinvestment Act – forcing lenders to take a more sympathetic approach to poor borrowers trying to get on the housing ladder.
(8) When this sequence was used to probe Southern blots of EcoRI-digested genomic DNA, a ladder of bands with increments of about 170 bp was observed.
(9) Of the big national companies, the only one to take a major hit was English National Opera, while there was also a big cut for the Lowry, and complete cuts for Theatre Royal Bury St Edmunds and touring companies including the long-standing Red Ladder.
(10) On SDS-PAGE analysis, HA showed a single band at 35 kDa under reduced conditions and numerous ladder bands between 35 kDa to more than 300 kDa under nonreduced conditions.
(11) Women, in particular, have difficulty in saving sufficiently for retirement as they often take time off work to raise a family, which can set them back on the career ladder and reduce the amount they can afford to put away for pensions.
(12) "We were extremely limited as we had such a small deposit, and knew the rate of interest we would pay back would reflect this, but considered this to be short term as we were getting on the ladder.
(13) Finally, by using whole cells, it was found that the lower-molecular-weight species of the ladder pattern selectively partitioned into the hydrophobic phase of a Triton X-114 phase partitioning system, and the higher-molecular-weight bands were found in the aqueous phase.
(14) LPS-stimulated murine macrophages indicate that the "ladder" complex reflects differential glycosylation of mature 17 kDa TNF.
(15) Our advice to parents is to take full advantage of the new rules to help secure their children a place on the property ladder,” he says.
(16) Emma Reynolds MP, Labour's shadow housing minister, said: "Any help for first-time buyers struggling to get on the property ladder is welcome.
(17) The pauses observed during translation generate subsets of smaller discrete peptides, visualized in the gels as ladders of variable relative intensities, appearing exclusively and concomitantly with the fibroin.
(18) The National Association of Estate Agents said: "This announcement has added a new rung to the property ladder, one within reach of thousands of young families."
(19) The staff at the Peacocks store in Pontypridd were attempting to be as cheerful as always, laughing and joking as they clambered up a ladder to tape a new sale sign ("biggest ever – 20-70% of everything") to the window.
(20) Meanwhile, millions of other people, unable to get a foot on the property ladder, also have little choice but to rent – sometimes into their 30s or even 40s.
Stepladder
Definition:
(n.) A portable set of steps.
Example Sentences:
(1) The red carpets are being unrolled, the paparazzi are installing their stepladders, the dressmakers are rushing their schmutters to the airport – the Cannes film festival is finally upon us.
(2) In the whole of plunge injuries occurred with a stepladder we found 12%.
(3) The selection of analgesics has to be rationalised using a sequential approach such as the WHO stepladder.
(4) That made me laugh: in one scene in Mahler, I had been required to stand on a stepladder, with an electrician holding me up by keeping a large hand on my bottom.
(5) Cleavage sites in the non-transformed covalently labelled receptor were identified in the "stepladder" of fragments of Mr, 85, 65, 49, 35, 27-30 kDa, generated in the absence of calcium, with an additional 78 kDa fragment in its presence.
(6) Experiments were performed at pH 5, 7, and 9 at 25 degrees C and pH 7 at 5 degrees C. Survival curves were "stepladder"-shaped, but concentration-time data generally conformed to Watson's Law.
(7) Baker spent eight hours a day walking up and down a stepladder, clocking up a total height of 50 miles, which allowed him to claim astronaut status.
(8) One monoclonal antibody bound to a carbohydrate epitope on both the broad band and the stepladder, indicating that it bound to the core of the lipopolysaccharide.
(9) Nobody wants a commemorative teacup of Kate on a stepladder doing the bathroom.
(10) The infantile malignant form was characterized by a complete lack of signal from the marrow alternating with a signal intensity equivalent to that of the intervertebral disks, resulting in a "stepladder" appearance.
(11) "We'll take a stepladder, a bucket of water, a bucket of leaves and dirt and filth, and a wind machine.
(12) In addition, SDS-PAGE indicated an amphiphile with a stepladder appearance made up of several components with m.w.
(13) The NOSPECS classification of Graves' eye disease is inadequate for a number of reasons: (a) poor characterization of the condition with no indication of disease activity, marked underrepresentation of eyelid position, and overrepresentation of corneal problems, (b) it represents neither a continuous nor stepladder progression of disease as the numbered classification would suggest, (c) parts of it are subjective, and (d) the gradings of classes 3, 5, and 6 are poor.
(14) He then threw stepladders and "other items" at police, and broke into the back of a lorry, where he stayed for 15 minutes passing planks of wood to other rioters.
(15) The accepted standard treatment method includes stepladder excision for extensive fistulas.
(16) Unlike the stepladder approach, this is simple and avoids extensive time consuming dissection.
(17) We have purified lipopolysaccharide from M. xanthus and have shown by silver staining that the lipopolysaccharide contains a heterogeneous population of molecules which migrate as a broad low-molecular-mass band (approximately 5 kilodaltons) and as a stepladder of about 30 higher-molecular-mass bands (15- to 70-kilodalton range).
(18) The stepladder bands contain lipopolysaccharide molecules with lipid A, core regions, and various numbers of O-antigen units.
(19) Case 1 and 2 were treated via a standard stepladder excision approach.
(20) Four of these five monoclonal antibodies bound to doublet bands in the stepladder, while the other monoclonal antibody bound to singlet bands in the stepladder.