(v. i.) A frame usually portable, of wood, metal, or rope, for ascent and descent, consisting of two side pieces to which are fastened cross strips or rounds forming steps.
(v. i.) That which resembles a ladder in form or use; hence, that by means of which one attains to eminence.
Example Sentences:
(1) This has been manageable, even beneficial to the economy when people slowly climbed the property ladder.
(2) Western blots of both the native alpha antigen and the cloned gene product demonstrate a regularly laddered pattern of heterogeneous polypeptides.
(3) He admitted the increased profile afforded him by appearances in movies such as Captain America , its forthcoming sequel The Winter Soldier and 2012's $1.5bn superhero ensemble piece The Avengers had helped him get a foot on the ladder as a film-maker.
(4) Methods employing electroosmotic flow in an untreated silica capillary were found to provide, at best, only partial resolution of the 23 fragments in a 1-kbp DNA ladder.
(5) Britons at the top of the social ladder are by far the most likely to have lied in order to get a job; 41% of social grade A have lied on a job application.
(6) They were thought to be caused by the rotor practice interfering with just-learned ladder skill consolidation, so that the gain in skill was not processed into long-term memory.
(7) Around the same time Clinton also beefed up President Carter's 1977 Community Reinvestment Act – forcing lenders to take a more sympathetic approach to poor borrowers trying to get on the housing ladder.
(8) When this sequence was used to probe Southern blots of EcoRI-digested genomic DNA, a ladder of bands with increments of about 170 bp was observed.
(9) Of the big national companies, the only one to take a major hit was English National Opera, while there was also a big cut for the Lowry, and complete cuts for Theatre Royal Bury St Edmunds and touring companies including the long-standing Red Ladder.
(10) On SDS-PAGE analysis, HA showed a single band at 35 kDa under reduced conditions and numerous ladder bands between 35 kDa to more than 300 kDa under nonreduced conditions.
(11) Women, in particular, have difficulty in saving sufficiently for retirement as they often take time off work to raise a family, which can set them back on the career ladder and reduce the amount they can afford to put away for pensions.
(12) "We were extremely limited as we had such a small deposit, and knew the rate of interest we would pay back would reflect this, but considered this to be short term as we were getting on the ladder.
(13) Finally, by using whole cells, it was found that the lower-molecular-weight species of the ladder pattern selectively partitioned into the hydrophobic phase of a Triton X-114 phase partitioning system, and the higher-molecular-weight bands were found in the aqueous phase.
(14) LPS-stimulated murine macrophages indicate that the "ladder" complex reflects differential glycosylation of mature 17 kDa TNF.
(15) Our advice to parents is to take full advantage of the new rules to help secure their children a place on the property ladder,” he says.
(16) Emma Reynolds MP, Labour's shadow housing minister, said: "Any help for first-time buyers struggling to get on the property ladder is welcome.
(17) The pauses observed during translation generate subsets of smaller discrete peptides, visualized in the gels as ladders of variable relative intensities, appearing exclusively and concomitantly with the fibroin.
(18) The National Association of Estate Agents said: "This announcement has added a new rung to the property ladder, one within reach of thousands of young families."
(19) The staff at the Peacocks store in Pontypridd were attempting to be as cheerful as always, laughing and joking as they clambered up a ladder to tape a new sale sign ("biggest ever – 20-70% of everything") to the window.
(20) Meanwhile, millions of other people, unable to get a foot on the property ladder, also have little choice but to rent – sometimes into their 30s or even 40s.
Streak
Definition:
(v. t.) To stretch; to extend; hence, to lay out, as a dead body.
(n.) A line or long mark of a different color from the ground; a stripe; a vein.
(n.) A strake.
(n.) The fine powder or mark yielded by a mineral when scratched or rubbed against a harder surface, the color of which is sometimes a distinguishing character.
(n.) The rung or round of a ladder.
(v. t.) To form streaks or stripes in or on; to stripe; to variegate with lines of a different color, or of different colors.
(v. t.) With it as an object: To run swiftly.
Example Sentences:
(1) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(2) Data from cases with myocardial bridges show that both fatty streaks and raised lesions are seldom observed in the region distal to myocardial bridge.
(3) Evx-1 RNA is first detected shortly before the onset of gastrulation in a region of ectoderm containing cells that will soon be found in the primitive streak.
(4) Gonadoblastoma is an unusual tumor that typically arises in a streak gonad or an abnormal testis of an individual having a Y chromosome.
(5) This study focuses on the expansion and maturation of the fatty streak in the aorta of Watanabe Heritable Hyperlipemic rabbits and comparably hypercholesterolemic fat-fed rabbits between 2 and 6 months duration of hypercholesterolemia.
(6) Fatty streaks were observed in 2nd decade involving only 7.5% of the total intimal surface and reaching to a maximum of 22.2% in the 3rd decade, followed by a gradual rise to 9.2% in 7th decade.
(7) Immunoreactivity in fatty streaks was located around collections of foam cells.
(8) The streaking phenomenon, as well as the tendency toward randomness, was discussed in terms of attentional anomalies.
(9) The high frequency of angioid streaks observed in patients with beta thalassemia and the severe complications observed in one patient render a thorough ophthalmoscopic examination and follow-up of such patients necessary for both early diagnosis and possible therapeutic intervention.
(10) On the back of some appalling results, including a six-game losing streak, the atmosphere at the game against Cardiff was toxic and the abuse intensely personal.
(11) As development proceeded during primitive streak stages, the visceral and parietal endoderm became positively stained.
(12) The mean survival period after angiography was 3.8 months, and the prognosis was not favorable in patients having "thread-and-streak" sign on angiography.
(13) A diet containing 0.3% cholesterol was given to male New Zealand rabbits for 16 weeks; this produced atherosclerotic lesions (fatty streaks) on 80% of the intimal surface of the thoracic aorta and on 45% of the intimal surface of the abdominal aorta.
(14) The area of highest density formed a nasal-temporal band suggestive of a visual streak.
(15) The horizontal streak of high rhodopsin levels is preferentially reduced in this retinopathy.
(16) Density distribution maps for neurons in the ganglion cell layer and the photoreceptor layer reveal the presence of a putative area centralis and a horizontal visual streak.
(17) Atherosclerotic lesions (mostly fatty streaks but some fibrous plaques) were present only in groups C and CL and were absent in groups L and N. The percentage of atherosclerotic intimal involvement was significantly greater in group CL than C (P less than 0.001).
(18) A unique pattern for a carbohydrate antigen is displayed by cells of the primitive streak; antigenicity is lost with de-epithelialisation and ingression, but is regained in a pericellular distribution on the mesoderm cells that emerge from the primitive streak.
(19) Grossly visible fatty streaks and fibrous plaques were not found in any of the swine aorta.
(20) The cluster lies just posterior to the definitive primitive streak in the extraembryonic mesoderm, separated from the embryo by the amniotic fold.