(superl.) Exceeding most other things of like kind in bulk, capacity, quantity, superficial dimensions, or number of constituent units; big; great; capacious; extensive; -- opposed to small; as, a large horse; a large house or room; a large lake or pool; a large jug or spoon; a large vineyard; a large army; a large city.
(superl.) Abundant; ample; as, a large supply of provisions.
(superl.) Full in statement; diffuse; full; profuse.
(superl.) Having more than usual power or capacity; having broad sympathies and generous impulses; comprehensive; -- said of the mind and heart.
(superl.) Free; unembarrassed.
(superl.) Unrestrained by decorum; -- said of language.
(superl.) Prodigal in expending; lavish.
(superl.) Crossing the line of a ship's course in a favorable direction; -- said of the wind when it is abeam, or between the beam and the quarter.
(adv.) Freely; licentiously.
(n.) A musical note, formerly in use, equal to two longs, four breves, or eight semibreves.
Example Sentences:
(1) For some time now, public opinion polls have revealed Americans' strong preference to live in comparatively small cities, towns, and rural areas rather than in large cities.
(2) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(3) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(4) These eight large plasmids had indistinguishable EcoRI restriction patterns.
(5) The adjacent gauge was separated from the ischemic segment by one large nonoccluded diagonal branch of the left anterior descending artery.
(6) IT can, therefore, be excluded almost with certainty that the meat would contain such large amounts of hormone residues.
(7) The small units described here could be inhibitory interneurons which convert the excitatory response of large units into inhibition.
(8) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(9) At the time, with a regular supply of British immigrants arriving in large numbers in Australia, Biggs was able to blend in well as "Terry Cook", a carpenter, so well in fact that his wife, Charmian, was able to join him with his three sons.
(10) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
(11) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(12) One patient with a large fistula angiographically had no oximetric evidence of shunt at cardiac catheterization.
(13) Their contour lengths varied from 0.28 to 51 micron, but unlike in the case of maize, a large difference was not observed in the distribution of molecular classes greater than 1.0 micron between N and S cytoplasms of sugar beet.
(14) The region containing the injection stop signal (iss) has been cloned and sequenced and found to contain numerous large repeats and inverted repeats which may be part of the iss.
(15) Chloroquine induced large cytoplasmic vacuoles, whereas the other drugs (quinacrine, 4,4'-diethylaminoethoxyhexestrol, chlorphentermine, iprindole, 1-chloro-amitriptyline, clomipramine) caused formation of lamellated or crystalloid inclusions as usually seen in drug-induced lipidosis.
(16) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(17) Of the 622 people interviewed, a large proportion (30.5%) believed that the first deciduous tooth should erupt between the age of 5-7 months; the next commonly mentioned time of tooth eruption was 7-9 months of age; and 50.3% of the respondents claimed to have seen a case of prematurely erupted primary teeth.
(18) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.
(19) The ratios in both groups were also compared with the ratios of a large group of normal subjects evaluated in a population survey.
(20) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
Little
Definition:
(a.) Small in size or extent; not big; diminutive; -- opposed to big or large; as, a little body; a little animal; a little piece of ground; a little hill; a little distance; a little child.
(a.) Short in duration; brief; as, a little sleep.
(a.) Small in quantity or amount; not much; as, a little food; a little air or water.
(a.) Small in dignity, power, or importance; not great; insignificant; contemptible.
(a.) Small in force or efficiency; not strong; weak; slight; inconsiderable; as, little attention or exertion;little effort; little care or diligence.
(a.) Small in extent of views or sympathies; narrow; shallow; contracted; mean; illiberal; ungenerous.
(n.) That which is little; a small quantity, amount, space, or the like.
(n.) A small degree or scale; miniature.
(adv.) In a small quantity or degree; not much; slightly; somewhat; -- often with a preceding it.
Example Sentences:
(1) Prior to oral feeding, little or no ELA was detected in stools and endotoxinemia was ascertained in only six of 45 infants (13%).
(2) 8.43am BST A little more from that Field interview on Today.
(3) The omission of Crossrail 2 from the Conservative manifesto , in which other infrastructure projects were listed, was the clearest sign yet that there is little appetite in a Theresa May government for another London-based scheme.
(4) Not only do they give employers no reason to turn them into proper jobs, but mini-jobs offer workers little incentive to work more because then they would have to pay tax.
(5) Some commentators have described his ship, now facing more delays after a decade in development, as little more than a Heath Robinson machine.
(6) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(7) The origin of the aorta and pulmonary artery from the right ventricle is a complicated and little studied congenital cardiac malformation.
(8) Today’s figures tell us little about the timing of the first increase in interest rates, which will depend on bigger picture news on domestic growth, pay trends and perceived downside risks in the global economy,” he said.
(9) It is a place that occupies two thirds of our planet but very little is known of vast swaths of it.
(10) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(11) Furthermore, little DNA relatedness was found between the type strain and a strain of C. natalensis.
(12) Displacement of a colinear line over the same range without an offset evoked little, if any, response.
(13) Little is so far known of the origin of this syndrome.
(14) Known as the Little House in the Garden, this temporary structure lasted over 50 years.
(15) Little difference exists between the proportion of programs that offer training in first-trimester techniques and the proportion that train in second-trimester techniques.
(16) A study of the time-course of the response during aortic stenosis of 30 min duration showed early release of renin from the innervated kidney at a time (5 min) when little release occurred from the denervated one.
(17) She loved us and we loved her.” “We would have loved to have had a little grandchild from her,” she says sadly.
(18) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(19) Stimulation with these electrodes were effective for inducing voiding with little residual volume after the recovery of bladder reflexes, 3 weeks after experimental spinal cord injury in the dog.
(20) Technical manipulations to improve resolution were time consuming and added little to the accuracy of the test.