(superl.) Exceeding most other things of like kind in bulk, capacity, quantity, superficial dimensions, or number of constituent units; big; great; capacious; extensive; -- opposed to small; as, a large horse; a large house or room; a large lake or pool; a large jug or spoon; a large vineyard; a large army; a large city.
(superl.) Abundant; ample; as, a large supply of provisions.
(superl.) Full in statement; diffuse; full; profuse.
(superl.) Having more than usual power or capacity; having broad sympathies and generous impulses; comprehensive; -- said of the mind and heart.
(superl.) Free; unembarrassed.
(superl.) Unrestrained by decorum; -- said of language.
(superl.) Prodigal in expending; lavish.
(superl.) Crossing the line of a ship's course in a favorable direction; -- said of the wind when it is abeam, or between the beam and the quarter.
(adv.) Freely; licentiously.
(n.) A musical note, formerly in use, equal to two longs, four breves, or eight semibreves.
Example Sentences:
(1) For some time now, public opinion polls have revealed Americans' strong preference to live in comparatively small cities, towns, and rural areas rather than in large cities.
(2) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(3) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(4) These eight large plasmids had indistinguishable EcoRI restriction patterns.
(5) The adjacent gauge was separated from the ischemic segment by one large nonoccluded diagonal branch of the left anterior descending artery.
(6) IT can, therefore, be excluded almost with certainty that the meat would contain such large amounts of hormone residues.
(7) The small units described here could be inhibitory interneurons which convert the excitatory response of large units into inhibition.
(8) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(9) At the time, with a regular supply of British immigrants arriving in large numbers in Australia, Biggs was able to blend in well as "Terry Cook", a carpenter, so well in fact that his wife, Charmian, was able to join him with his three sons.
(10) Theresa May signals support for UK-EU membership deal Read more Faull’s fix, largely accepted by Britain, also ties the hands of national governments.
(11) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(12) One patient with a large fistula angiographically had no oximetric evidence of shunt at cardiac catheterization.
(13) Their contour lengths varied from 0.28 to 51 micron, but unlike in the case of maize, a large difference was not observed in the distribution of molecular classes greater than 1.0 micron between N and S cytoplasms of sugar beet.
(14) The region containing the injection stop signal (iss) has been cloned and sequenced and found to contain numerous large repeats and inverted repeats which may be part of the iss.
(15) Chloroquine induced large cytoplasmic vacuoles, whereas the other drugs (quinacrine, 4,4'-diethylaminoethoxyhexestrol, chlorphentermine, iprindole, 1-chloro-amitriptyline, clomipramine) caused formation of lamellated or crystalloid inclusions as usually seen in drug-induced lipidosis.
(16) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(17) Of the 622 people interviewed, a large proportion (30.5%) believed that the first deciduous tooth should erupt between the age of 5-7 months; the next commonly mentioned time of tooth eruption was 7-9 months of age; and 50.3% of the respondents claimed to have seen a case of prematurely erupted primary teeth.
(18) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.
(19) The ratios in both groups were also compared with the ratios of a large group of normal subjects evaluated in a population survey.
(20) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
Tic
Definition:
(n.) A local and habitual convulsive motion of certain muscles; especially, such a motion of some of the muscles of the face; twitching; velication; -- called also spasmodic tic.
Example Sentences:
(1) A case of epidermoid tumor presenting with a painful tic convulsif was reported.
(2) This treatment was given to 11 patients with Huntington's chorea (ChH), 4 with faciolingual dyskinesis (DFL), 3 with torticollis spasmodicus (TS), 3 with maladie des tics (MT) and 8 with dyskinesia following treatment with L-dopa (MP).
(3) The highest predictive values for the exclusion of TiC are shown by inconspicuous concentration capacity accompanied by normal ammonia excretion, total acid excretion, water diuresis, free water clearance or urine dilution capacity.
(4) In an effort to test this hypothesis, the relationships between organism concentrations and water chemistry parameters that have the potential to alter Cd availability including pH, calcium (Ca), total organic carbon (TOC) and total inorganic carbon (TIC) were examined.
(5) Tics are modified by multiple psychological contents (aggressive or sexual impulses, imitation of others) which tend to become independent of their origin.
(6) On the basis of the achieved results the author comes to the conclusion that in the pathogenesis of a pseudoneurotic tic an important role is being played by a premorbid insufficiency of the motor analyzer.
(7) The authors hypothesize that neurotransmitter abnormalities existing in Down's syndrome may predispose such individuals to basal ganglia dysfunction and the subsequent development of tics.
(8) All tics subsided before the age of 20 years, only to recur after the age of 60 years, once again including both motor and vocal tics that changed in location and severity slowly over time.
(9) The observation of a young north african afflicted with a tic disorder suggests an underlying meaning in the apparently confused motoric discharges, thanks to psychodrama and to ethnopsychoanalytic consultations with the family.
(10) Only PIP or TIC + SUL or TAZ were able to inhibit at least 90% of tested strains.
(11) Five of our 7 patients had a positive family history of tics, and 2 a confirmed family history of gout.
(12) When diagnostic criteria were broadened to include any tics in co-twins, concordance rates were 77% and 23% for MZ and DZ pairs, respectively.
(13) Associated psychopathology was common: 38% received an anxiety disorder diagnosis; 29% received a mood disorder diagnosis; tics were observed in 24%.
(14) Pharmacological intervention, using clonidine, also did not reduce tic frequency.
(15) Further there are associations between a family history of tics and obsessive compulsive disorder in the subsequent generation.
(16) The narrative drivers are pretty slack – improbable dialogue ("I'm a very wealthy man, Miss Steele, and I have expensive and absorbing hobbies"); lame characterisation; irritating tics (a constant war between Steele's "subconscious", which is always fainting or putting on half-moon glasses, and her "inner goddess", who is forever pouting and stamping); and an internal monologue that goes like this … "Holy hell, he's hot!
(17) The activity of TIC against Bacteroides fragilis was improved up to 64-fold by clavulanic acid, with a definite but less pronounced effect on the non-fragilis Bacteroides species.
(18) The tic occurred 40 to 50 times per minute on its peak at age 16.
(19) In a direct interview study, the perinatal experiences of 31 TS patients were compiled in an effort to identify risk factors associated with tic severity.
(20) The majority of patients with tic douloureux are successfully treated by pharmacotherapy with phenytoin or carbamazepine.