(a.) Having the effect of loosening or opening the intestines, and relieving from constipation; -- opposed to astringent.
(n.) A laxative medicine. See the Note under Cathartic.
Example Sentences:
(1) There was a history of facial edema and constipation, which have been managed with "Kanpo medicine (Chinese medicine)" and laxatives for several years.
(2) There was no significant difference between the laxatives used.
(3) IN EXAMINATION OF THE SMALL INTESTINE, SHORTENED TRANSIT TIME AND IMPROVED QUALITY WERE ACHIEVED BY USING THE FOLLOWING ITEMS OF REGIMEN: 1, No laxative; 2, nothing by mouth for 8 hours before examination; 3, 600 ml of micropulverized barium sulfate; 4, patient to lie in right decubitus position for at least one hour between films; and 5, ingestion of 200 ml of cool tap water a half hour after the start of the examination.
(4) Patients were then randomized in 2 groups, both receiving standard treatment during 2 months (low-salt diet--70 to 90 mEq of Na per day, stopping diuretics and laxatives, elastic stockings).
(5) In all patients careful bowel preparation was carried out by low residue diet, laxatives, enemas and antibiotics.
(6) Urinary data indicate that a large percentage (50%) of the drug was eliminated renally despite administration of multiple doses of activated charcoal, cholestyramine and hyperosmotic laxatives.
(7) In contrast to manometry, electromyographic methods using an endoluminal probe enable continuous colonic motor recordings over a long colonic segment for at least 24 h, and consequently studies following the course of laxative effects after oral administration, the classical therapeutic route, are possible.
(8) In contrast, the laxative potentiated the responses of the longitudinal muscle of guinea-pig isolated ileum and the rat stomach strip to the agonists, particularly PGE2.
(9) Stimulation of peristalsis or a decrease of intraluminal pressure has been described manometrically after intraluminal administration of laxatives including senna.
(10) The aim of the present investigation is therefore to study the absorption and the plasma level profile and to correlate plasma level profile and laxative effect after the administration of various dosage forms.
(11) The results suggest that azapropazone can be given together with antacids and laxatives since there is no significant interaction.
(12) From this controlled double-blind study it is not possible to draw any definite conclusions regarding the efficacy of bulk laxatives on geriatric patients.
(13) Furthermore, these data demonstrate a previously unrecognised interaction between a commonly prescribed laxative--lactulose, and atenolol and hydrochlorothiazide.
(14) In total 90% of the women received drugs, excluding laxatives, oxytocics and long-term medication, vitamins and iron.
(15) Both types of abuse were associated with the following behaviors: running away; considering hurting oneself; suicide attempts; and the use of drugs, pot (marijuana), cigarettes, and laxatives.
(16) To evaluate these two laxative regimens the following parameters were monitored: quantity and quality of the feces and of additional laxatives used for regular defecation; acceptance by the patient; costs per patient and day.
(17) In the differential diagnosis of gastrointestinal disturbances the possibility of laxative abuse is considered either too late or not at all.
(18) Nor is there any difference between the two laxatives.
(19) It is noted that children who took more pills often had fewer or no symptoms, and that laxatives increased the incidence of vomiting.
(20) After adjusting for potential confounders (including age, sex, relevant medical conditions, health status, cognitive impairment, use of alcohol, depression and use of other medications), the following medications were found to be important risk factors for multiple falls: diazepam [odds ratio (OR): 3.7, 95% confidence interval (CI): 1.5-9.3], diltiazem (OR: 1.8, 95% CI: 0.8-4.1), diuretics (OR: 1.8, 95% CI: 1.2-2.8) and laxatives (OR: 2.1, 95% CI: 1.0-4.5).
Purgative
Definition:
(a.) Having the power or quality of purging; cathartic.
(n.) A purging medicine; a cathartic.
Example Sentences:
(1) The timely discovery of the cause of the disease leads to the discontinuance of the use of diuretics and purgatives and to complete recovery.
(2) The effectiveness of short-term, low-dose, preoperative oral administration of neomycin and erythromycin base combined with vigorous purgation in reducing the incidence of wound infections and other septic complications of elective colon and rectal operations has been studied in a prospective, randomized, double-blind, clinical trial.
(3) These results agree with recent observations on the effects of senna in rats and mice, and do not support earlier claims that myenteric neurons are killed by anthraquinone purgatives.
(4) This paper reported the results of clinical observation on a treatment with Semen Persical decoction for purgation with addition (SPDPA) in type II diabetes mellitus.
(5) E. hortense adult worms were recovered from one patient after a treatment and purgation.
(6) The standard preparation for cleansing the colon usually involves dietary restrictions, purgatives, and enemas.
(7) The purgative activities of 18 different dihydroxyanthracene derivatives, including free anthraquinones and anthrones, were investigated by determining their influence on the water, sodium and potassium absorption in the gastrointestinal tract by direct injection of the solutions in Tyrode to the rat colon in situ.
(8) Some cultural groups also have a tradition of giving purgatives to the newborn, a practice which exacerbates the dehydration effects of not breastfeeding.
(9) Rats and mice were given purgative doses of sennosides in their drinking water for 4 and 5 months, respectively.
(10) These actions can lead to a new dark age of "chemotherapeutic blood letting and purgatives" under the guise of higher ethical purposes.
(11) Poor prognosis was most commonly linked to use of purgatives.
(12) 140 patients were prepared with conventional enema and purgatives and a Neomycin-metronidazole prophylaxis.
(13) Compared to women who had never used purgatives, current purgative users were 4.1 times more likely to smoke (44% vs 11%) and 2.7 times as likely to use drugs (33% vs 12%).
(14) Purgatives, emetics, opium, cinchona bark, camphor, potassium nitrate and mercury were among the most widely used drugs.
(15) Purgation was induced by oral administration of arecoline and the purge examined for cestodes.
(16) From pseudocarps of R. wichuraiana, three quercetin glycosides, isoquercitrin, hyperin and quercetin 3-O-beta-D-glucuronide were isolated similarly, but no purgative components of R. multiflora were detected.
(17) The prevalence of binge-eating more than once a week, together with self-induced vomiting or purgative use, was 3.6% in the nursing school students, 2.1% in the college women, and 2.9% in the total sample.
(18) In many groups, substitute prelacteal feeds were given, while in others, practices such as the use of purgatives exacerbated the risk of dehydration in the infant.
(19) In mice experimentally invaded by H. nana it was shown that the water extraction of breadfruit tree substance is rather less effective than its ethanol extraction and has some purgative action, which increases the therapeutic effect.
(20) Twenty percent had at some time used diet pills, but only 4% were currently users; 13% had at some time used purgatives (vomiting, laxatives, or diuretics), but only 5% were current users.