(a.) Having the effect of loosening or opening the intestines, and relieving from constipation; -- opposed to astringent.
(n.) A laxative medicine. See the Note under Cathartic.
Example Sentences:
(1) There was a history of facial edema and constipation, which have been managed with "Kanpo medicine (Chinese medicine)" and laxatives for several years.
(2) There was no significant difference between the laxatives used.
(3) IN EXAMINATION OF THE SMALL INTESTINE, SHORTENED TRANSIT TIME AND IMPROVED QUALITY WERE ACHIEVED BY USING THE FOLLOWING ITEMS OF REGIMEN: 1, No laxative; 2, nothing by mouth for 8 hours before examination; 3, 600 ml of micropulverized barium sulfate; 4, patient to lie in right decubitus position for at least one hour between films; and 5, ingestion of 200 ml of cool tap water a half hour after the start of the examination.
(4) Patients were then randomized in 2 groups, both receiving standard treatment during 2 months (low-salt diet--70 to 90 mEq of Na per day, stopping diuretics and laxatives, elastic stockings).
(5) In all patients careful bowel preparation was carried out by low residue diet, laxatives, enemas and antibiotics.
(6) Urinary data indicate that a large percentage (50%) of the drug was eliminated renally despite administration of multiple doses of activated charcoal, cholestyramine and hyperosmotic laxatives.
(7) In contrast to manometry, electromyographic methods using an endoluminal probe enable continuous colonic motor recordings over a long colonic segment for at least 24 h, and consequently studies following the course of laxative effects after oral administration, the classical therapeutic route, are possible.
(8) In contrast, the laxative potentiated the responses of the longitudinal muscle of guinea-pig isolated ileum and the rat stomach strip to the agonists, particularly PGE2.
(9) Stimulation of peristalsis or a decrease of intraluminal pressure has been described manometrically after intraluminal administration of laxatives including senna.
(10) The aim of the present investigation is therefore to study the absorption and the plasma level profile and to correlate plasma level profile and laxative effect after the administration of various dosage forms.
(11) The results suggest that azapropazone can be given together with antacids and laxatives since there is no significant interaction.
(12) From this controlled double-blind study it is not possible to draw any definite conclusions regarding the efficacy of bulk laxatives on geriatric patients.
(13) Furthermore, these data demonstrate a previously unrecognised interaction between a commonly prescribed laxative--lactulose, and atenolol and hydrochlorothiazide.
(14) In total 90% of the women received drugs, excluding laxatives, oxytocics and long-term medication, vitamins and iron.
(15) Both types of abuse were associated with the following behaviors: running away; considering hurting oneself; suicide attempts; and the use of drugs, pot (marijuana), cigarettes, and laxatives.
(16) To evaluate these two laxative regimens the following parameters were monitored: quantity and quality of the feces and of additional laxatives used for regular defecation; acceptance by the patient; costs per patient and day.
(17) In the differential diagnosis of gastrointestinal disturbances the possibility of laxative abuse is considered either too late or not at all.
(18) Nor is there any difference between the two laxatives.
(19) It is noted that children who took more pills often had fewer or no symptoms, and that laxatives increased the incidence of vomiting.
(20) After adjusting for potential confounders (including age, sex, relevant medical conditions, health status, cognitive impairment, use of alcohol, depression and use of other medications), the following medications were found to be important risk factors for multiple falls: diazepam [odds ratio (OR): 3.7, 95% confidence interval (CI): 1.5-9.3], diltiazem (OR: 1.8, 95% CI: 0.8-4.1), diuretics (OR: 1.8, 95% CI: 1.2-2.8) and laxatives (OR: 2.1, 95% CI: 1.0-4.5).
Purge
Definition:
(v. t.) To cleanse, clear, or purify by separating and carrying off whatever is impure, heterogeneous, foreign, or superfluous.
(v. t.) To operate on as, or by means of, a cathartic medicine, or in a similar manner.
(v. t.) To clarify; to defecate, as liquors.
(v. t.) To clear of sediment, as a boiler, or of air, as a steam pipe, by driving off or permitting escape.
(v. t.) To clear from guilt, or from moral or ceremonial defilement; as, to purge one of guilt or crime.
(v. t.) To clear from accusation, or the charge of a crime or misdemeanor, as by oath or in ordeal.
(v. t.) To remove in cleansing; to deterge; to wash away; -- often followed by away.
(v. i.) To become pure, as by clarification.
(v. i.) To have or produce frequent evacuations from the intestines, as by means of a cathartic.
(v. t.) The act of purging.
(v. t.) That which purges; especially, a medicine that evacuates the intestines; a cathartic.
Example Sentences:
(1) Thus photosensitization using AISPc may be an effective method of purging marrow autografts in some cases of AML.
(2) Current investigations include the development of more effective cytoreductive regimens, use of recombinant hematopoietic growth factors, improvement of marrow purging techniques, and enhancement of cell-mediated anti-leukemic activity in patients receiving autologous marrow transplants.
(3) Direct detection of chromium in milk, using only argon as purge gas, was inferior.
(4) Indiana Indiana began to purge inactive voters in may 2014 by sending postcards to all registered voters.
(5) Sequential application of the two methods (immunorosette depletion with CD19 McAb followed by a complement lysis with CD9 and CD10 McAbs) led to superior results in causing a 4- to 5-log purging effect.
(6) Reduced caloric intake, a hallmark of both disorders, is manifested by self-induced starvation in anorexia and by binge eating and gastrointestinal purging in bulimia.
(7) Mafosfamide is presently used for the purging of bone marrow in autologous bone marrow transplantation in the treatment of acute leukemia.
(8) The two log difference in the surviving fraction of CFU-L and CFU-S after 120 min exposure to 42.5 degrees C suggests that hyperthermia ex vivo may be a suitable purging method for autologous bone marrow transplantation.
(9) There are already calls for large protests in Egypt this week demanding fair trials and retribution, as well as measures to purge former regime officials from political and economic life.
(10) Our data suggest that this new strategy shows potential for more effective ex vivo marrow purging in autologous marrow transplantation for acute lymphoblastic leukemia.
(11) In summary, laser light-induced photosensitization with MC540 has a selective cytotoxicity to leukemic cells; therefore, this procedure may be useful for purging neoplastic cells from autologous BM.
(12) Pretransplantation regimes were: total-body irradiation (TBI), 456; busulfan plus cyclophosphamide (BU-CY) 174; marrow purging with mafosfamide, 269 (corresponding to 26% of all patients in CR1 and 41% in CR2).
(13) Phase 1 studies of "in vivo purging" with a monovalent CD3 antibody (Clark et al., 1989), and also with a genetically engineered humanized IgG1 (CAMPATH-1H) (Hale et al., 1988b) suggest that these limitations can be overcome.
(14) Despite patient and disease heterogeneity, different sources of hemopoietic stem cells (allogeneic or autologous, bone marrow or blood), ex vivo purging of autografts, and different preparative regimens, some general recommendations can be made: (1) Allogeneic BMT should be reserved for patients under age 50, where transplant-related mortality can be expected not to exceed 30%; 40% will achieve CR with a 3-year relapse-free survival expectation of 70%, and (2) With autologous transplantation, low mortality under 10% and marked therapeutic benefit (greater than 30% CR, 80% overall survival at greater than 3 years) seem to be achievable mainly if performed when tumor bulk is low and standard doses of therapy are still effective.
(15) The transfusion purging leukocytes may diminish the occasions of alloimmunization.
(16) The Brotherhood's Libyan incarnation won only 10% of the vote in last year's congressional elections, but gained support with its campaign to mandate wholesale purges of Gaddafi-era officials.
(17) We feel that this system will prove valuable for monitoring ex vivo tumor removal in future clinical studies and should be considered for use in other purging trials.
(18) The quantitative determination of the efficacy of these purging methods is generally difficult.
(19) The government began aggressively purging the heads of cultural and academic institutions (a notable number of them Jewish and liberal intellectuals suspected of a “foreign” mindset) and installing in their stead true believers in the Magyar way.
(20) The result of our study in patients in second and third remission using in vitro purging of bone marrow with monoclonal antibodies PM-81 and AML2-23 are encouraging, as are the studies of purging with 4-HC.