(a.) Having the effect of loosening or opening the intestines, and relieving from constipation; -- opposed to astringent.
(n.) A laxative medicine. See the Note under Cathartic.
Example Sentences:
(1) There was a history of facial edema and constipation, which have been managed with "Kanpo medicine (Chinese medicine)" and laxatives for several years.
(2) There was no significant difference between the laxatives used.
(3) IN EXAMINATION OF THE SMALL INTESTINE, SHORTENED TRANSIT TIME AND IMPROVED QUALITY WERE ACHIEVED BY USING THE FOLLOWING ITEMS OF REGIMEN: 1, No laxative; 2, nothing by mouth for 8 hours before examination; 3, 600 ml of micropulverized barium sulfate; 4, patient to lie in right decubitus position for at least one hour between films; and 5, ingestion of 200 ml of cool tap water a half hour after the start of the examination.
(4) Patients were then randomized in 2 groups, both receiving standard treatment during 2 months (low-salt diet--70 to 90 mEq of Na per day, stopping diuretics and laxatives, elastic stockings).
(5) In all patients careful bowel preparation was carried out by low residue diet, laxatives, enemas and antibiotics.
(6) Urinary data indicate that a large percentage (50%) of the drug was eliminated renally despite administration of multiple doses of activated charcoal, cholestyramine and hyperosmotic laxatives.
(7) In contrast to manometry, electromyographic methods using an endoluminal probe enable continuous colonic motor recordings over a long colonic segment for at least 24 h, and consequently studies following the course of laxative effects after oral administration, the classical therapeutic route, are possible.
(8) In contrast, the laxative potentiated the responses of the longitudinal muscle of guinea-pig isolated ileum and the rat stomach strip to the agonists, particularly PGE2.
(9) Stimulation of peristalsis or a decrease of intraluminal pressure has been described manometrically after intraluminal administration of laxatives including senna.
(10) The aim of the present investigation is therefore to study the absorption and the plasma level profile and to correlate plasma level profile and laxative effect after the administration of various dosage forms.
(11) The results suggest that azapropazone can be given together with antacids and laxatives since there is no significant interaction.
(12) From this controlled double-blind study it is not possible to draw any definite conclusions regarding the efficacy of bulk laxatives on geriatric patients.
(13) Furthermore, these data demonstrate a previously unrecognised interaction between a commonly prescribed laxative--lactulose, and atenolol and hydrochlorothiazide.
(14) In total 90% of the women received drugs, excluding laxatives, oxytocics and long-term medication, vitamins and iron.
(15) Both types of abuse were associated with the following behaviors: running away; considering hurting oneself; suicide attempts; and the use of drugs, pot (marijuana), cigarettes, and laxatives.
(16) To evaluate these two laxative regimens the following parameters were monitored: quantity and quality of the feces and of additional laxatives used for regular defecation; acceptance by the patient; costs per patient and day.
(17) In the differential diagnosis of gastrointestinal disturbances the possibility of laxative abuse is considered either too late or not at all.
(18) Nor is there any difference between the two laxatives.
(19) It is noted that children who took more pills often had fewer or no symptoms, and that laxatives increased the incidence of vomiting.
(20) After adjusting for potential confounders (including age, sex, relevant medical conditions, health status, cognitive impairment, use of alcohol, depression and use of other medications), the following medications were found to be important risk factors for multiple falls: diazepam [odds ratio (OR): 3.7, 95% confidence interval (CI): 1.5-9.3], diltiazem (OR: 1.8, 95% CI: 0.8-4.1), diuretics (OR: 1.8, 95% CI: 1.2-2.8) and laxatives (OR: 2.1, 95% CI: 1.0-4.5).
Senna
Definition:
(n.) The leaves of several leguminous plants of the genus Cassia. (C. acutifolia, C. angustifolia, etc.). They constitute a valuable but nauseous cathartic medicine.
(n.) The plants themselves, native to the East, but now cultivated largely in the south of Europe and in the West Indies.
Example Sentences:
(1) Stimulation of peristalsis or a decrease of intraluminal pressure has been described manometrically after intraluminal administration of laxatives including senna.
(2) The number and frequency of the side-effects reported in the senna treatment week were very much higher (p less than 0.001) than in the lactulose week.
(3) However, a fat-free diet reduced the PG production drastically in the colonic lumen both in senna-free rats and in senna-treated rats.
(4) Several contributions of this senna symposium bring complementary information of utmost interest.
(5) These results agree with recent observations on the effects of senna in rats and mice, and do not support earlier claims that myenteric neurons are killed by anthraquinone purgatives.
(6) The results suggest that neither dimethicone nor senna improves the visibility of abdominal organs in ultrasound examination.
(7) Pharmacological research on senna started at the beginning of this century.
(8) Hamilton added: “It’s a very humbling experience to equal Ayrton Senna [with three wins] who meant so much to me and still does.
(9) In order to investigate the toxic effects of long-term treatment with anthraquinone laxatives, rats were fed either chocolate alone, or chocolate adulterated with senna or danthron (1,8-dihydroxyanthraquinone) for 5 months.
(10) In addition, in a high-risk group for colorectal cancer, 31 persons received PEG or senna preparation and their REP was not significantly different from that of 23 examined without these preparations.
(11) He won a Bafta for his 2011 study of the Formula One star Ayrton Senna.
(12) Satisfactory cleansing results were achieved with Bisacodyl as well as with Senna (98.3 vs. 95%).
(13) Was he referring to their general relationship or something more specific, namely the start of the 1990 Japanese Grand Prix when Senna took out Prost?
(14) The day before endoscopy either Bisacodyl or extractum Sennae was given to 120 patients.
(15) The senna was administrated as ground senna pods mixed with milk chocolate.
(16) No peristaltic response was stimulated in the rectum, either with activated senna or with rheinanthrone.
(17) Hamilton’s promise to take a page out of his idol Ayrton Senna’s book – he later described this as “a joke” but it was no such thing at the time – lent a frisson to the first corner.
(18) Oral administration of senna pod extract (7-5-90 mg kg-1) produced a dose-dependent increase in the number of soft faeces excreted by normal rats.
(19) Senna, containing only dianthrones as active substances, is still in the center of scientific research and merits this special attention.
(20) The effectiveness and acceptability of three colon cleansing regimens for colonoscopy were compared in a prospective study in 271 patients stratified as in- and out-patients and randomly assigned to either I) a diet and Senna laxative (X-prep), combined with a saline enema (n = 88); II) 41 of a polyethylene glycol electrolyte lavage solution (Golytely) (n = 90); or III) a combined regimen of Cascara-Salax laxative (PicoSalax) and 1.51 Golytely (n = 93).