(n.) That which loosens; -- esp., a muscle which by its contraction loosens some part.
Example Sentences:
(1) There was a history of facial edema and constipation, which have been managed with "Kanpo medicine (Chinese medicine)" and laxatives for several years.
(2) There was no significant difference between the laxatives used.
(3) IN EXAMINATION OF THE SMALL INTESTINE, SHORTENED TRANSIT TIME AND IMPROVED QUALITY WERE ACHIEVED BY USING THE FOLLOWING ITEMS OF REGIMEN: 1, No laxative; 2, nothing by mouth for 8 hours before examination; 3, 600 ml of micropulverized barium sulfate; 4, patient to lie in right decubitus position for at least one hour between films; and 5, ingestion of 200 ml of cool tap water a half hour after the start of the examination.
(4) Patients were then randomized in 2 groups, both receiving standard treatment during 2 months (low-salt diet--70 to 90 mEq of Na per day, stopping diuretics and laxatives, elastic stockings).
(5) In all patients careful bowel preparation was carried out by low residue diet, laxatives, enemas and antibiotics.
(6) Urinary data indicate that a large percentage (50%) of the drug was eliminated renally despite administration of multiple doses of activated charcoal, cholestyramine and hyperosmotic laxatives.
(7) In contrast to manometry, electromyographic methods using an endoluminal probe enable continuous colonic motor recordings over a long colonic segment for at least 24 h, and consequently studies following the course of laxative effects after oral administration, the classical therapeutic route, are possible.
(8) In contrast, the laxative potentiated the responses of the longitudinal muscle of guinea-pig isolated ileum and the rat stomach strip to the agonists, particularly PGE2.
(9) Stimulation of peristalsis or a decrease of intraluminal pressure has been described manometrically after intraluminal administration of laxatives including senna.
(10) The aim of the present investigation is therefore to study the absorption and the plasma level profile and to correlate plasma level profile and laxative effect after the administration of various dosage forms.
(11) The results suggest that azapropazone can be given together with antacids and laxatives since there is no significant interaction.
(12) From this controlled double-blind study it is not possible to draw any definite conclusions regarding the efficacy of bulk laxatives on geriatric patients.
(13) Furthermore, these data demonstrate a previously unrecognised interaction between a commonly prescribed laxative--lactulose, and atenolol and hydrochlorothiazide.
(14) In total 90% of the women received drugs, excluding laxatives, oxytocics and long-term medication, vitamins and iron.
(15) Both types of abuse were associated with the following behaviors: running away; considering hurting oneself; suicide attempts; and the use of drugs, pot (marijuana), cigarettes, and laxatives.
(16) To evaluate these two laxative regimens the following parameters were monitored: quantity and quality of the feces and of additional laxatives used for regular defecation; acceptance by the patient; costs per patient and day.
(17) In the differential diagnosis of gastrointestinal disturbances the possibility of laxative abuse is considered either too late or not at all.
(18) Nor is there any difference between the two laxatives.
(19) It is noted that children who took more pills often had fewer or no symptoms, and that laxatives increased the incidence of vomiting.
(20) After adjusting for potential confounders (including age, sex, relevant medical conditions, health status, cognitive impairment, use of alcohol, depression and use of other medications), the following medications were found to be important risk factors for multiple falls: diazepam [odds ratio (OR): 3.7, 95% confidence interval (CI): 1.5-9.3], diltiazem (OR: 1.8, 95% CI: 0.8-4.1), diuretics (OR: 1.8, 95% CI: 1.2-2.8) and laxatives (OR: 2.1, 95% CI: 1.0-4.5).
Loosen
Definition:
(v. t.) To make loose; to free from tightness, tension, firmness, or fixedness; to make less dense or compact; as, to loosen a string, or a knot; to loosen a rock in the earth.
(v. t.) To free from restraint; to set at liberty..
(v. t.) To remove costiveness from; to facilitate or increase the alvine discharges of.
(v. i.) To become loose; to become less tight, firm, or compact.
Example Sentences:
(1) There is a gradual loosening of the adolescent's emotional dependence on her parents and a transfer of dependency ties to peers.
(2) The torques, although not large enough to dislodge the socket immediately, are repetitive and so may contribute to loosening.
(3) Femoral endosteal bone loss has been shown to be part of the natural aging process and may be a factor in femoral component loosening following total hip arthroplasty (THA).
(4) Seventeen of these were due to infection or loosening of the prosthesis.
(5) Loosening of the sutures and keratitis were the main complications in the postoperative course.
(6) Electric birefringence studies suggest that methylation may result in both interparticle cross-linking and some localised loosening of the DNA-protein complex complex.
(7) Two tibial components (2%) were believed to be mechanically loose, but no revisions for mechanical loosening were done.
(8) An artificial joint that articulates with full fluid film lubrication could greatly reduce wear and frictional torque and hence reduce the incidence of loosening and inflammatory tissue reaction.
(9) Aseptic loosening is the most common mode of failure for total knee replacements.
(10) The criteria of failure of pedicular instrumentation or "death" of an implant were defined as 1) screw bending, 2) screw breakage, 3) infection, 4) loosening of implants, 5) any rod or plate hardware problems, or 6) removal of hardware due to a neurologic complication.
(11) In the areas of disorganized collagen fibres cervical fibroblasts seemed to be activated characterized by fine granular loosening of the cytoplasma, dilated cisternae of rough endoplasmatic reticulum, vacuolized enlarged mitochondria and an increased number of cytoplasmatic vesicles close to the cell surface.
(12) Loosening of the tightly folded "native" structure of the two proteins following their synthesis in a rabbit reticulocyte lysate was assayed by the acquisition of protease sensitivity (pODHFR and pOCAT) or by the loss of enzyme activity (pOCAT).
(13) We concluded that the acetabular component of the Wagner prosthesis is prone to early loosening and that the early loosening is potentiated by a foreign-body response to debris resulting from arthroplastic wear.
(14) I think that is where we will see the most immediate loosening up of restrictions,” Handjani said.
(15) The reduction in the rate of aseptic loosening of the socket in our series, compared with the higher rates reported in similar long-term studies in which other acetabular components were used, supports the conclusion that there is enhanced longevity of acetabular fixation when a metal-backed acetabular component is used in cemented total hip arthroplasty.
(16) The loosening of such interactions is believed to induce conformational changes, which will alter ion transport systems necessary to the propagation of neural impulses.
(17) Main changes of upper compartments were showed on the bilaminar zone, including disc perforation and anterior displacement and capsular loosening.
(18) Significant problems included abnormal posture in the wrist, roentgenographic evidence of loosening in the finger metacarpophalangeals, extensor lag in the metacarpophalangeal of the thumb, and lack of motion in the proximal interphalangeal joint of the finger.
(19) China's government and media have launched a broadside against Japan's move to loosen the bonds on its powerful military, casting it as a threat to Asian security.
(20) However, because loosening and sinking of the prosthesis were significant, a ceramic total prosthesis was designed in 1980 to be used without cement.