What's the difference between lead and open?

Lead


Definition:

  • (n.) An open way in an ice field.
  • (n.) A lode.
  • (n.) One of the elements, a heavy, pliable, inelastic metal, having a bright, bluish color, but easily tarnished. It is both malleable and ductile, though with little tenacity, and is used for tubes, sheets, bullets, etc. Its specific gravity is 11.37. It is easily fusible, forms alloys with other metals, and is an ingredient of solder and type metal. Atomic weight, 206.4. Symbol Pb (L. Plumbum). It is chiefly obtained from the mineral galena, lead sulphide.
  • (n.) An article made of lead or an alloy of lead
  • (n.) A plummet or mass of lead, used in sounding at sea.
  • (n.) A thin strip of type metal, used to separate lines of type in printing.
  • (n.) Sheets or plates of lead used as a covering for roofs; hence, pl., a roof covered with lead sheets or terne plates.
  • (n.) A small cylinder of black lead or plumbago, used in pencils.
  • (v. t.) To cover, fill, or affect with lead; as, continuous firing leads the grooves of a rifle.
  • (v. t.) To place leads between the lines of; as, to lead a page; leaded matter.
  • (v. t.) To guide or conduct with the hand, or by means of some physical contact connection; as, a father leads a child; a jockey leads a horse with a halter; a dog leads a blind man.
  • (v. t.) To guide or conduct in a certain course, or to a certain place or end, by making the way known; to show the way, esp. by going with or going in advance of. Hence, figuratively: To direct; to counsel; to instruct; as, to lead a traveler; to lead a pupil.
  • (v. t.) To conduct or direct with authority; to have direction or charge of; as, to lead an army, an exploring party, or a search; to lead a political party.
  • (v. t.) To go or to be in advance of; to precede; hence, to be foremost or chief among; as, the big sloop led the fleet of yachts; the Guards led the attack; Demosthenes leads the orators of all ages.
  • (v. t.) To draw or direct by influence, whether good or bad; to prevail on; to induce; to entice; to allure; as, to lead one to espouse a righteous cause.
  • (v. t.) To guide or conduct one's self in, through, or along (a certain course); hence, to proceed in the way of; to follow the path or course of; to pass; to spend. Also, to cause (one) to proceed or follow in (a certain course).
  • (v. t.) To begin a game, round, or trick, with; as, to lead trumps; the double five was led.
  • (v. i.) To guide or conduct, as by accompanying, going before, showing, influencing, directing with authority, etc.; to have precedence or preeminence; to be first or chief; -- used in most of the senses of lead, v. t.
  • (v. t.) To tend or reach in a certain direction, or to a certain place; as, the path leads to the mill; gambling leads to other vices.
  • (n.) The act of leading or conducting; guidance; direction; as, to take the lead; to be under the lead of another.
  • (n.) precedence; advance position; also, the measure of precedence; as, the white horse had the lead; a lead of a boat's length, or of half a second.
  • (n.) The act or right of playing first in a game or round; the card suit, or piece, so played; as, your partner has the lead.
  • (n.) The course of a rope from end to end.
  • (n.) The width of port opening which is uncovered by the valve, for the admission or release of steam, at the instant when the piston is at end of its stroke.
  • (n.) the distance of haul, as from a cutting to an embankment.
  • (n.) The action of a tooth, as a tooth of a wheel, in impelling another tooth or a pallet.

Example Sentences:

  • (1) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
  • (2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
  • (3) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
  • (4) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
  • (5) These are typically runaway processes in which global temperature rises lead to further releases of CO², which in turn brings about more global warming.
  • (6) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
  • (7) It would be fascinating to see if greater local government involvement in running the NHS in places such as Manchester leads over the longer term to a noticeable difference in the financial outlook.
  • (8) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
  • (9) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
  • (10) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
  • (11) The availability and success of changes in reproductive technology should lead to a reappraisal of the indications for hysterectomy, especially in young women.
  • (12) Photoirradiation of F1 in the presence of the analog leads to inactivation depending linearly on the incorporation of label.
  • (13) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
  • (14) The new Somali government has enthusiastically embraced the new deal and created a taskforce, bringing together the government, lead donors (the US, UK, EU, Norway and Denmark), the World Bank and civil society.
  • (15) Suggested is a carefully prepared system of cycling videocassettes, to effect the dissemination of current medical information from leading medical centers to medical and paramedical people in the "bush".
  • (16) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
  • (17) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
  • (18) In the case presented, overdistension of a jejunostomy catheter balloon led to intestinal obstruction and pressure necrosis (of the small bowel), with subsequent abscess formation leading to death from septicemia.
  • (19) This is rapidly followed by a gamut of changes leading to demyelination.
  • (20) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.

Open


Definition:

  • (a.) Free of access; not shut up; not closed; affording unobstructed ingress or egress; not impeding or preventing passage; not locked up or covered over; -- applied to passageways; as, an open door, window, road, etc.; also, to inclosed structures or objects; as, open houses, boxes, baskets, bottles, etc.; also, to means of communication or approach by water or land; as, an open harbor or roadstead.
  • (a.) Free to be used, enjoyed, visited, or the like; not private; public; unrestricted in use; as, an open library, museum, court, or other assembly; liable to the approach, trespass, or attack of any one; unprotected; exposed.
  • (a.) Free or cleared of obstruction to progress or to view; accessible; as, an open tract; the open sea.
  • (a.) Not drawn together, closed, or contracted; extended; expanded; as, an open hand; open arms; an open flower; an open prospect.
  • (a.) Without reserve or false pretense; sincere; characterized by sincerity; unfeigned; frank; also, generous; liberal; bounteous; -- applied to personal appearance, or character, and to the expression of thought and feeling, etc.
  • (a.) Not concealed or secret; not hidden or disguised; exposed to view or to knowledge; revealed; apparent; as, open schemes or plans; open shame or guilt.
  • (a.) Not of a quality to prevent communication, as by closing water ways, blocking roads, etc.; hence, not frosty or inclement; mild; -- used of the weather or the climate; as, an open season; an open winter.
  • (a.) Not settled or adjusted; not decided or determined; not closed or withdrawn from consideration; as, an open account; an open question; to keep an offer or opportunity open.
  • (a.) Free; disengaged; unappropriated; as, to keep a day open for any purpose; to be open for an engagement.
  • (a.) Uttered with a relatively wide opening of the articulating organs; -- said of vowels; as, the an far is open as compared with the a in say.
  • (a.) Uttered, as a consonant, with the oral passage simply narrowed without closure, as in uttering s.
  • (a.) Not closed or stopped with the finger; -- said of the string of an instrument, as of a violin, when it is allowed to vibrate throughout its whole length.
  • (a.) Produced by an open string; as, an open tone.
  • (n.) Open or unobstructed space; clear land, without trees or obstructions; open ocean; open water.
  • (v. t.) To make or set open; to render free of access; to unclose; to unbar; to unlock; to remove any fastening or covering from; as, to open a door; to open a box; to open a room; to open a letter.
  • (v. t.) To spread; to expand; as, to open the hand.
  • (v. t.) To disclose; to reveal; to interpret; to explain.
  • (v. t.) To make known; to discover; also, to render available or accessible for settlements, trade, etc.
  • (v. t.) To enter upon; to begin; as, to open a discussion; to open fire upon an enemy; to open trade, or correspondence; to open a case in court, or a meeting.
  • (v. t.) To loosen or make less compact; as, to open matted cotton by separating the fibers.
  • (v. i.) To unclose; to form a hole, breach, or gap; to be unclosed; to be parted.
  • (v. i.) To expand; to spread out; to be disclosed; as, the harbor opened to our view.
  • (v. i.) To begin; to commence; as, the stock opened at par; the battery opened upon the enemy.
  • (v. i.) To bark on scent or view of the game.

Example Sentences:

  • (1) says Gregg Wallace opening the new series of Celebrity MasterChef (Mon-Fri, 2.15pm, BBC1).
  • (2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
  • (3) His son, Karim Makarius, opened the gallery to display some of the legacy bequeathed to him by his father in 2009, as well as the work of other Argentine photographers and artists – currently images by contemporary photographer Facundo de Zuviria are also on show.
  • (4) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
  • (5) Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial.
  • (6) By hybridization studies, three plasmids in two forms (open circular and supercoiled) were detected in the strain A24.
  • (7) It is the only fully-fledged casino to open in the region, outside Lebanon.
  • (8) Sixty-six patients were followed for 12 months in an open safety study.
  • (9) The PUP founder made the comments at a voters’ forum and press conference during an open day held at his Palmer Coolum Resort, where he invited the electorate to see his giant robotic dinosaur park, memorabilia including his car collection and a concert by Dean Vegas, an Elvis impersonator.
  • (10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
  • (11) An opening wedge osteotomy is then directed posterior-dorsal to anterior-plantar, to effectively plantarflex the posterior aspect of the calcaneus.
  • (12) … or a theatre and concert hall There are a total of 16 ghost stations on the Paris metro; stops that were closed or never opened.
  • (13) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
  • (14) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
  • (15) 'The French see it as an open and shut case,' says a Paris-based diplomat.
  • (16) The White House denied there had been an agreement, but said it was open in principle to such negotations.
  • (17) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
  • (18) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
  • (19) He also plans to build a processing facility where tourists can gain firsthand experience of the fisheries industry, and to open a restaurant.
  • (20) He had been just asked to open their new town hall, in the hope he might donate a Shakespeare statue.