What's the difference between lead and principal?

Lead


Definition:

  • (n.) An open way in an ice field.
  • (n.) A lode.
  • (n.) One of the elements, a heavy, pliable, inelastic metal, having a bright, bluish color, but easily tarnished. It is both malleable and ductile, though with little tenacity, and is used for tubes, sheets, bullets, etc. Its specific gravity is 11.37. It is easily fusible, forms alloys with other metals, and is an ingredient of solder and type metal. Atomic weight, 206.4. Symbol Pb (L. Plumbum). It is chiefly obtained from the mineral galena, lead sulphide.
  • (n.) An article made of lead or an alloy of lead
  • (n.) A plummet or mass of lead, used in sounding at sea.
  • (n.) A thin strip of type metal, used to separate lines of type in printing.
  • (n.) Sheets or plates of lead used as a covering for roofs; hence, pl., a roof covered with lead sheets or terne plates.
  • (n.) A small cylinder of black lead or plumbago, used in pencils.
  • (v. t.) To cover, fill, or affect with lead; as, continuous firing leads the grooves of a rifle.
  • (v. t.) To place leads between the lines of; as, to lead a page; leaded matter.
  • (v. t.) To guide or conduct with the hand, or by means of some physical contact connection; as, a father leads a child; a jockey leads a horse with a halter; a dog leads a blind man.
  • (v. t.) To guide or conduct in a certain course, or to a certain place or end, by making the way known; to show the way, esp. by going with or going in advance of. Hence, figuratively: To direct; to counsel; to instruct; as, to lead a traveler; to lead a pupil.
  • (v. t.) To conduct or direct with authority; to have direction or charge of; as, to lead an army, an exploring party, or a search; to lead a political party.
  • (v. t.) To go or to be in advance of; to precede; hence, to be foremost or chief among; as, the big sloop led the fleet of yachts; the Guards led the attack; Demosthenes leads the orators of all ages.
  • (v. t.) To draw or direct by influence, whether good or bad; to prevail on; to induce; to entice; to allure; as, to lead one to espouse a righteous cause.
  • (v. t.) To guide or conduct one's self in, through, or along (a certain course); hence, to proceed in the way of; to follow the path or course of; to pass; to spend. Also, to cause (one) to proceed or follow in (a certain course).
  • (v. t.) To begin a game, round, or trick, with; as, to lead trumps; the double five was led.
  • (v. i.) To guide or conduct, as by accompanying, going before, showing, influencing, directing with authority, etc.; to have precedence or preeminence; to be first or chief; -- used in most of the senses of lead, v. t.
  • (v. t.) To tend or reach in a certain direction, or to a certain place; as, the path leads to the mill; gambling leads to other vices.
  • (n.) The act of leading or conducting; guidance; direction; as, to take the lead; to be under the lead of another.
  • (n.) precedence; advance position; also, the measure of precedence; as, the white horse had the lead; a lead of a boat's length, or of half a second.
  • (n.) The act or right of playing first in a game or round; the card suit, or piece, so played; as, your partner has the lead.
  • (n.) The course of a rope from end to end.
  • (n.) The width of port opening which is uncovered by the valve, for the admission or release of steam, at the instant when the piston is at end of its stroke.
  • (n.) the distance of haul, as from a cutting to an embankment.
  • (n.) The action of a tooth, as a tooth of a wheel, in impelling another tooth or a pallet.

Example Sentences:

  • (1) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
  • (2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
  • (3) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
  • (4) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
  • (5) These are typically runaway processes in which global temperature rises lead to further releases of CO², which in turn brings about more global warming.
  • (6) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
  • (7) It would be fascinating to see if greater local government involvement in running the NHS in places such as Manchester leads over the longer term to a noticeable difference in the financial outlook.
  • (8) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
  • (9) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
  • (10) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
  • (11) The availability and success of changes in reproductive technology should lead to a reappraisal of the indications for hysterectomy, especially in young women.
  • (12) Photoirradiation of F1 in the presence of the analog leads to inactivation depending linearly on the incorporation of label.
  • (13) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
  • (14) The new Somali government has enthusiastically embraced the new deal and created a taskforce, bringing together the government, lead donors (the US, UK, EU, Norway and Denmark), the World Bank and civil society.
  • (15) Suggested is a carefully prepared system of cycling videocassettes, to effect the dissemination of current medical information from leading medical centers to medical and paramedical people in the "bush".
  • (16) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
  • (17) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
  • (18) In the case presented, overdistension of a jejunostomy catheter balloon led to intestinal obstruction and pressure necrosis (of the small bowel), with subsequent abscess formation leading to death from septicemia.
  • (19) This is rapidly followed by a gamut of changes leading to demyelination.
  • (20) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.

Principal


Definition:

  • (a.) Highest in rank, authority, character, importance, or degree; most considerable or important; chief; main; as, the principal officers of a Government; the principal men of a state; the principal productions of a country; the principal arguments in a case.
  • (a.) Of or pertaining to a prince; princely.
  • (n.) A leader, chief, or head; one who takes the lead; one who acts independently, or who has controlling authority or influence; as, the principal of a faction, a school, a firm, etc.; -- distinguished from a subordinate, abettor, auxiliary, or assistant.
  • (n.) The chief actor in a crime, or an abettor who is present at it, -- as distinguished from an accessory.
  • (n.) A chief obligor, promisor, or debtor, -- as distinguished from a surety.
  • (n.) One who employs another to act for him, -- as distinguished from an agent.
  • (n.) A thing of chief or prime importance; something fundamental or especially conspicuous.
  • (n.) A capital sum of money, placed out at interest, due as a debt or used as a fund; -- so called in distinction from interest or profit.
  • (n.) The construction which gives shape and strength to a roof, -- generally a truss of timber or iron, but there are roofs with stone principals. Also, loosely, the most important member of a piece of framing.
  • (n.) In English organs the chief open metallic stop, an octave above the open diapason. On the manual it is four feet long, on the pedal eight feet. In Germany this term corresponds to the English open diapason.
  • (n.) A heirloom; a mortuary.
  • (n.) The first two long feathers of a hawk's wing.
  • (n.) One of turrets or pinnacles of waxwork and tapers with which the posts and center of a funeral hearse were formerly crowned.
  • (n.) A principal or essential point or rule; a principle.

Example Sentences:

  • (1) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (2) While stereology is the principal technique, particularly in its application to the parenchyma, other compartments such as the airways and vasculature demand modifications or different methods altogether.
  • (3) Chromatography and immunoassays are the two principal techniques used in research and clinical laboratories for the measurement of drug concentrations in biological fluids.
  • (4) This paper reports, principally, the caries results of the first three surveys of 5, 12 and 5-year-olds undertaken at the end of 1987, 1988 and 1989, respectively.
  • (5) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
  • (6) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
  • (7) Mononuclear phagocytic cells from patients with either principal form of leprosy functioned similarly to normal monocytes in phagocytosis while their fungicidal activity for C. pseudotropicalis was statistically significantly altered and was more evident in the lepromatous than in the tuberculoid type.
  • (8) In the terminal segment of the hamster epididymidis there was some evidence of micro-merocrine protein secretion a the level of the principal cells and clear evidence of granular secretion in the light cells, presumable of glycoproteins.
  • (9) In the analysis of background fluorescence, the principal components were, as for the two-step technique, autofluorescence and propidium spectral overlap.
  • (10) However, at Period B, neutrophil numbers in the BAL fluid were increased in the principal but not in the control animals.
  • (11) Principal conclusions are: 1) rapid change to predominantly heterosexual HIV transmission can occur in North America, with serious societal impact; 2) gender-specific clinical features can lead to earlier diagnosis of HIV infection in women; 3) HIV infection in women does not pursue an inherently more rapid course than that observed in men.
  • (12) The concentrations of the principal extratesticular androgens and estradiol do not seem to have a quantitative influence on these androphilic proteins either.
  • (13) A principal function of GPIb is its attachment to von Willebrand Factor (vWF) on injured blood vessels which leads to the adhesion of platelets to these vessels.
  • (14) The principal variables influencing a particular configuration and their effects are indicated.
  • (15) The principal form of HMTs produced by these human peripheral blood monocytes has been subjected to biochemical, functional, and serological characterization.
  • (16) Micronutrient antioxidants such as alpha-tocopherol, the principal lipid-soluble antioxidant, assume potential significance because levels can be manipulated by dietary measures without resulting in side effects.
  • (17) Cytochrome oxidase histochemistry revealed patchy patterns of the enzyme activity in transverse sections through the caudal part of the ventral subnucleus of the principal sensory trigeminal nucleus, interpolar spinal trigeminal nucleus, and layer IV of the caudal spinal trigeminal nucleus in the cat.
  • (18) 3. an up-to-date review of the principal methods and systems used to measure the sedimentation rate--Automation of the Westergren initial methodology.
  • (19) • Queen Margaret Union, one of the University of Glasgow's two student unions, says 200 students there are marching on the principal's office at the moment to present an anti-cuts petition.
  • (20) This observation provides corroboration for the identification of the principal CCK-I neuron in the rat olfactory bulb as the centrally projecting middle tufted cell.