(n.) A complex, nitrogenous phosphorized substance widely distributed through the animal body, and especially conspicuous in the brain and nerve tissue, in yolk of eggs, and in the white blood corpuscles.
Example Sentences:
(1) We similarly evaluated the ability of other phospholipids to form stable foam at various concentrations and ethanol volume fractions and found: bovine brain sphingomyelin greater than dipalmitoyl 3-sn-phosphatidylcholine greater than egg sphingomyelin greater than egg lecithin greater than phosphatidylglycerol.
(2) These observations suggest that the liver secretes disk-shaped lipid bilayer particles which represent both the nascent form of high density lipoproteins and preferred substrate for lecithin-cholesterol acyltransferase.
(3) Saturated acyl residues predominated in lysolecithin and unsaturated ones in acids released by hydrolysis of egg lecithin.
(4) The permeability properties of planar lipid bilayers made from egg lecithin, n-decane and a long-chain secondary amine (n-lauryl [trialkylmethyl]amine) are described.
(5) In the absence of lipid transfer protein activity in incubations containing purified lecithin: cholesterol acyltransferase, 73% of the esterified [3H]cholesterol was in HDL, 25% in LDL and only 1% in VLDL.
(6) perfringens was studied by gel-diffusion in agarose-lecithin gels.
(7) Several short-chain asymmetric lecithins with a total of 14 carbons in the acyl chains (ranging from 1-lauroyl-2-acetylphosphatidylcholine to 1-hexanoyl-2-octanoylphosphatidylcholine) have been synthesized and characterized.
(8) It was shown that indocyanin green (ICG) test, prothrombin time (PT), lecithin cholesterol acyltransferase (LCAT), gamma-globulin, age of patients and total bilirubin appeared to be important factors to discriminate the subjected patients into two groups.
(9) We synthesized lecithinized superoxide dismutase (PC-SOD), in which a lecithin derivative was covalently bound to recombinant human SOD.
(10) The high level of serum free cholesterol in the female obese rat is not due to a deficiency in lecithin-cholesterol acyltransferase activity.
(11) Mixed micelles (MM) formed from glycocholic acid and lecithin are suited to solubilize lipophilic drugs for intravenous use.
(12) Basal lecithin release from placental tissue was unaffected by any steroid concentration.
(13) Later, animals exposed to lifelong 5 or 2% soy lecithin preparations were hypoactive, had poor postural reflexes, and showed attenuated morphine analgesia.
(14) It has been concluded that purified lecithin: cholesterol acyltransferase is capable of increasing the size of HDL3 towards that of HDL2 but that other factors must operate in vivo to modulate the chemical composition of the enlarged particles.
(15) Compared to the group of controls, the group treated with Bromhexine metabolit VIII, as well as to the group treated with Betamethason, significantly higher values with regard to the content of total phospholipids, lecithine and palmitic acid could be found in the fetal rat lungs.
(16) In egg lecithin with a variety of polyunsaturated side chains, the side chains with the greater number of double bonds are preferentially displaced by high concentrations of cholesterol, which accounts for the increase in the ratio of outer to inner -N(+)(CH(3))(3) groups.
(17) The lecithins of the primary hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene (DAB) and host liver of rat were isolated, and the individual molecular species were estimated quantitatively by combined thin-layer and gaschromatographic analysis and specific enzymic hydrolysis.
(18) On lecithin agar, interpretation was easier, phospholipase A was detectable, and opaque zones were visible 1 or 2 days earlier than on egg yolk agar.
(19) On the contrary, cell incubation with lecithin liposomes resulted in cholesterol depletion.
(20) Both the relative decrease in the mass of disaturated lecithins in the BA washes and the increase in the percentage of esterified unsaturated fatty acids in the lecithins may be directly related to the reduced lung function reported to occur during the course of murine M. pulmonis pneumonia.
Phosphatidylcholine
Definition:
Example Sentences:
(1) We similarly evaluated the ability of other phospholipids to form stable foam at various concentrations and ethanol volume fractions and found: bovine brain sphingomyelin greater than dipalmitoyl 3-sn-phosphatidylcholine greater than egg sphingomyelin greater than egg lecithin greater than phosphatidylglycerol.
(2) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(3) Increasing concentrations of cholesterol monotonically increase the dipole potential of egg phosphatidylcholine monolayers, from 415 mV with no cholesterol to 493 mV with equimolar cholesterol.
(4) This value may be compared to a Kd of 7.3 pM obtained by the same method for the interaction of DF-VIIa with TF1-263 reconstituted into phosphatidylcholine vesicles.
(5) Separation of PL by thin-layer chromatography revealed a prevalence of phosphatidylcholine followed by phosphatidylethanolamine.
(6) The phosphatidylcholine and phosphatidylethanolamine had distinctive fatty acid distributions for position sn-2 of the triacylglycerol had a predominance of unsaturated fatty acids of which 18:1 (69.9%) was the major component.
(7) Phosphatidylcholine dispersed on Celite was rapidly solubilized by neutral bovine serum albumin solutions.
(8) Growth of C. albicans in the presence of AGE affected the yeast lipid in a number of ways: the total lipid content was decreased; garlic-grown yeasts had a higher level of phosphatidylserines and a lower level of phosphatidylcholines; in addition to free sterols and sterol esters, C. albicans accumulated esterified steryl glycosides; the concentration of palmitic acid (16:0) and oleic acid (18:1) increased and that of linoleic acid (18:2) and linolenic acid (18:3) decreased.
(9) In terms of segmental motion and anisotropy of packing the lipoprotein-X bilayer closely resembles a model bilayer system consisting of phosphatidylcholine, lysophosphatidylcholine, sphingomyelin and cholesterol mixed in the same molar ratio as in lipoprotein-X.
(10) CCK-OP and PMA activated phospholipase A (PLA) which liberated lysophosphatidylcholine (LPC) and free fatty acids from membrane phosphatidylcholine.
(11) cAMP decreased the incorporation of choline into phosphatidylcholine, but did not change the flux of metabolites through the step catalyzed by CTP:phosphocholine cytidylyltransferase.
(12) Biochem Pharmacol 40: 489-497, 1990), we showed that the inhibitory potency of gentamicin on the activity of lysosomal phospholipases, measured towards phosphatidylcholine included in negatively-charged liposomes, is markedly influenced by the nature of the acidic phospholipid used (phosphatidylinositol, phosphatidylserine, phosphatidic acid), whereas the binding of the drug to the three types of liposomes is similar.
(13) The 32P labelling of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) was not affected.
(14) The decrease in cardiac phosphatidylcholine and phosphatidylethanolamine content was prevented by iloprost, whereas the decrease in cardiolipin content was unaltered.
(15) Fe2+ and L-ascorbic acid induced oxidation of cholesterol was investigated in liposomes of egg yolk phosphatidylcholine (PC).
(16) Using the experimental model of the everted sac prepared from rat jejuna, kinetic studies on [14C]oleic acid uptake from bile salt micelles were conducted in the presence and absence of phosphatidylcholine.
(17) Phosphatidylcholine of high specific radioactivity was prepared biosynthetically in good yield from [Me-(14)C]choline by using Saccharomyces cerevisiae.
(18) On prolonged UV-A illumination the ESR spectrum of 16-doxylstearic acid in dimyristoyl phosphatidylcholine vesicles loaded with 8-methoxypsoralen changed dramatically as a second broad component gradually appeared.
(19) A chemiluminescence-high performance liquid chromatography (CL-HPLC) system was newly developed and used for the hydroperoxide-specific determination of phosphatidylcholine hydroperoxide (PCOOH) in human plasma.
(20) SM cultures exposed to [3H]choline incorporated about 90% of the radioactivity to phosphatidylcholine (PC) and 10% to sphingomyelin (SPM).