(n.) A cutaneous disease which first appears as blebs or as reddish, shining, slightly prominent spots, with spreading edges. These are often followed by an eruption of dark or yellowish prominent nodules, frequently producing great deformity. In one variety of the disease, anaesthesia of the skin is a prominent symptom. In addition there may be wasting of the muscles, falling out of the hair and nails, and distortion of the hands and feet with destruction of the bones and joints. It is incurable, and is probably contagious.
Example Sentences:
(1) The differential diagnosis is more complex in Hawaii due to the presence of granulomatous diseases such as tuberculosis and leprosy.
(2) Leprosy is an uncommon disease in Saudi population.
(3) Mononuclear phagocytic cells from patients with either principal form of leprosy functioned similarly to normal monocytes in phagocytosis while their fungicidal activity for C. pseudotropicalis was statistically significantly altered and was more evident in the lepromatous than in the tuberculoid type.
(4) Serum levels of vitamins A and E, zinc and iron were determined in healthy control subjects and lepromatous leprosy patients belonging to an eastern state of India.
(5) A rare coincidence of cutaneous Rhinosporidiosis and Lepromatous leprosy is reported.
(6) In order to study the polyspecificities of human autoantibodies expressed during infection with Mycobacterium leprae we prepared human monoclonal antibodies derived from the fusion of peripheral blood lymphocytes of a patient with lepromatous leprosy to the human lymphoblastoid line GM 4672.
(7) The present report is a continuation of our earlier studies on the complex interaction between undernutrition and leprosy.
(8) It is known that the impairment of cell-mediated immunity (CM) exists in lepromatous leprosy patients.
(9) Age specific prevalence rates of leprosy after examining more than 80% of population from these colonies are compared with data derived from normal slums situated elsewhere in the city.
(10) The possible epidemiological significance of these findings for the transmission of leprosy in man is discussed.
(11) Consistently higher antigen positivity rates for the 35-, 12-, and 30- to 40-kDa components of M. leprae were observed in lepromatous leprosy patients than in tuberculoid leprosy patients.
(12) The results suggest that macrophages from patients with either tuberculoid or lepromatous leprosy are not by themselves capable of lysing live M. leprae.
(13) In 83 per cent of cases the nephrotic syndrome was due to minimal change disease, focal segmental glomerulosclerosis, mesangiocapillary glomerulonephritis, membranous usually secondary to tuberculosis or leprosy, was present in only 34 patients.
(14) Histopathologically, the lesions display caseating and noncaseating dermal granulomas that mimic those seen in tuberculosis, tuberculoid leprosy, sarcoidosis, and other diseases.
(15) Leprosy is one of the leading causes of corneal hyposensitivity.
(16) The presence of high anti-EBV antibody titers in lepromatous leprosy suggests that cell-mediated immunity is a significant factor in host response to EBV infection.
(17) Overall in the contacts, 71.7% were Mitsuda positive and 93.6% showed seropositivity, without regard to their age, sex, or leprosy type of their index case.
(18) In the nine index leprosy cases the pattern of responsiveness to the purified antigens paralleled that to whole sonicates from M. leprae and BCG.
(19) When incidence and prevalence of leprosy are low, testing with these antigens would not be cost effective, unless applied to high risk individuals.
(20) The protocol was devised by first evaluating a range of kits in London using a battery of African and non-African sera and then field testing 1455 sera in Malaŵi, which included 184 sera from leprosy patients and 60 sera from syphilis patients to check for cross-reactivity.
Leprous
Definition:
(a.) Infected with leprosy; pertaining to or resembling leprosy.
(a.) Leprose.
Example Sentences:
(1) It is very difficult to say whether heart disease was due to any other cause associated with leprosy or due to leprous affection of myocardium.
(2) The production of reversal reactions in leprous nude mice in response to adoptively transferred CMI was studied in a quantitative fashion.
(3) It is suggested that Lazarine leprosy may result from enhanced lepromatous leprous infection occurring as a result of protein malnutrition.
(4) We detected substantial amounts of mycobacterial antigen in 16 leprous lymph nodes using anti-BCG by the peroxidase anti-peroxidase method.
(5) The present report describes a similar study, using TNS treatment in attempts to accelerate healing of chronic leprous ulcers that had resisted treatment for several months or years.
(6) With an immunoperoxidase method to localize lysozyme in leprous tissues, two distinct staining patterns were found, granular and saccular.
(7) In 1856 it was decided that all leprous patients should be examined by the local doctor (District Health Officer), and registered in a national leprosy register.
(8) Few studies have been published on large series of leprous neuritis patients treated surgically.
(9) The study demonstrates a clear therapeutic effect for low-frequency TNS in patients with leprous ulcers.
(10) In a yeast extract, glycerol and sheep serum containing medium, slow but abundant growth of mycobacteria occurred when media were inoculated with M. leprae isolated from leprous tissues of armadillos (Dasypus novemcinctus Linn.).
(11) Furthermore, all leprosy patients with B8 had leprous member(s) in their family.
(12) It would be a great thing if one of [the] alternatives [aspirants] garners a large enough number of votes to show thinking Nigerians that there could be a third force, because in reality, both the [incumbent] PDP and the [opposition] APC are rotten fingers of the same leprous hand,” wrote Chxta , a prominent Nigerian blogger.
(13) The hepatitis B virus markers were studied on 553 leprous sera and 100 controls sera.
(14) For eighty-six cases of leprous paralysis of the intrinsic muscles of the hand, a modified Bunnell opponensplasty (transfer of a finger flexor) was done.
(15) From none of these liver homogenates were acid-fast bacilli grown on culture in Löwenstein-Jensen medium.The alterations in liver functions were more consistently seen when acid-fast bacilli were associated with the presence of leprous granulomatous lesions.
(16) In the dermal hypersensitivity assay, the guinea pigs sensitized with soluble antigens of M. lepraemurium only responded to the antigens of M. lepraemurium, M. leprae and partly to M. scrofulaceum, but not to other antigens, including lepromin and leprous serum globulins.
(17) Twelve cases were of diabetic neuropathy (DN), nine of Guillain-Barre syndrome (GBS), eight of idiopathic, six of leprous, three of toxic neuropathy and one each of acute intermittent porphyria (AIP) and carcinomatous neuropathy.
(18) A list of published applications includes use in therapy for postherpetic neuralgia, increased peripheral circulation, itching, varicose ulcers, ischemic ulcers, diabetic neuropathy, leprous neuritis, would healing, increased survival of skin flaps, Raynaud's phenomenon, scleroderma, esophageal dysmotility, and glossodynia.
(19) Mycobacteria were isolated from pooled leprous tissues of an armadillo.
(20) In view of the phagocytic propensity of schwann cells for M. leprae as the important factor in leprous neuritis, TC preparations of gliomas, (in addition to acoustic schwannomas and meningiomas), were inoculated with two mycobacteria, M. scrofulaceum and the ICRC bacillus.