(n.) A cutaneous disease which first appears as blebs or as reddish, shining, slightly prominent spots, with spreading edges. These are often followed by an eruption of dark or yellowish prominent nodules, frequently producing great deformity. In one variety of the disease, anaesthesia of the skin is a prominent symptom. In addition there may be wasting of the muscles, falling out of the hair and nails, and distortion of the hands and feet with destruction of the bones and joints. It is incurable, and is probably contagious.
Example Sentences:
(1) The differential diagnosis is more complex in Hawaii due to the presence of granulomatous diseases such as tuberculosis and leprosy.
(2) Leprosy is an uncommon disease in Saudi population.
(3) Mononuclear phagocytic cells from patients with either principal form of leprosy functioned similarly to normal monocytes in phagocytosis while their fungicidal activity for C. pseudotropicalis was statistically significantly altered and was more evident in the lepromatous than in the tuberculoid type.
(4) Serum levels of vitamins A and E, zinc and iron were determined in healthy control subjects and lepromatous leprosy patients belonging to an eastern state of India.
(5) A rare coincidence of cutaneous Rhinosporidiosis and Lepromatous leprosy is reported.
(6) In order to study the polyspecificities of human autoantibodies expressed during infection with Mycobacterium leprae we prepared human monoclonal antibodies derived from the fusion of peripheral blood lymphocytes of a patient with lepromatous leprosy to the human lymphoblastoid line GM 4672.
(7) The present report is a continuation of our earlier studies on the complex interaction between undernutrition and leprosy.
(8) It is known that the impairment of cell-mediated immunity (CM) exists in lepromatous leprosy patients.
(9) Age specific prevalence rates of leprosy after examining more than 80% of population from these colonies are compared with data derived from normal slums situated elsewhere in the city.
(10) The possible epidemiological significance of these findings for the transmission of leprosy in man is discussed.
(11) Consistently higher antigen positivity rates for the 35-, 12-, and 30- to 40-kDa components of M. leprae were observed in lepromatous leprosy patients than in tuberculoid leprosy patients.
(12) The results suggest that macrophages from patients with either tuberculoid or lepromatous leprosy are not by themselves capable of lysing live M. leprae.
(13) In 83 per cent of cases the nephrotic syndrome was due to minimal change disease, focal segmental glomerulosclerosis, mesangiocapillary glomerulonephritis, membranous usually secondary to tuberculosis or leprosy, was present in only 34 patients.
(14) Histopathologically, the lesions display caseating and noncaseating dermal granulomas that mimic those seen in tuberculosis, tuberculoid leprosy, sarcoidosis, and other diseases.
(15) Leprosy is one of the leading causes of corneal hyposensitivity.
(16) The presence of high anti-EBV antibody titers in lepromatous leprosy suggests that cell-mediated immunity is a significant factor in host response to EBV infection.
(17) Overall in the contacts, 71.7% were Mitsuda positive and 93.6% showed seropositivity, without regard to their age, sex, or leprosy type of their index case.
(18) In the nine index leprosy cases the pattern of responsiveness to the purified antigens paralleled that to whole sonicates from M. leprae and BCG.
(19) When incidence and prevalence of leprosy are low, testing with these antigens would not be cost effective, unless applied to high risk individuals.
(20) The protocol was devised by first evaluating a range of kits in London using a battery of African and non-African sera and then field testing 1455 sera in Malaŵi, which included 184 sera from leprosy patients and 60 sera from syphilis patients to check for cross-reactivity.
Tuberculosis
Definition:
(n.) A constitutional disease characterized by the production of tubercles in the internal organs, and especially in the lungs, where it constitutes the most common variety of pulmonary consumption.
Example Sentences:
(1) The differential diagnosis is more complex in Hawaii due to the presence of granulomatous diseases such as tuberculosis and leprosy.
(2) The course of urogenital tuberculosis is complicated by unspecific bacterial infections of the urinary tract and nephrolithiasis.
(3) We identified four distinct clinical patterns in the 244 patients with true positive MAI infections: (a) pulmonary nodules ("tuberculomas") indistinguishable from pulmonary neoplasms (78 patients); (b) chronic bronchitis or bronchiectasis with sputum repeatedly positive for MAI or granulomas on biopsy (58 patients, virtually all older white women); (c) cavitary lung disease and scattered pulmonary nodules mimicking M. tuberculosis infection (12 patients); (d) diffuse pulmonary infiltrations in immunocompromised hosts, primarily patients with AIDS (96 patients).
(4) The radiologic findings on conventional examinations (plain films and cholangiograms) in a large group of patients with proven hepatobiliary tuberculosis are reviewed.
(5) Other organisms found together with N. miningitidis were H. influenzae (2 cases), S. dysgalactiae (1 case) and M. tuberculosis (1 case).
(6) The results of the examination of the tuberculosis cases detected during 7 years among the annually screened population are given.
(7) In view of its infrequent and vague presentation, care is required to avoid overlooking the diagnosis of abdominal tuberculosis, particularly in the immigrant population.
(8) Two years' experience of a simple serological test for the diagnosis of tuberculosis has been evaluated.
(9) A diagnosis of unilateral tuberculosis of the conjunctiva was established in a 75-year-old female patient eight years after the first manifestations of disease.
(10) Differential diagnosis must include renal tuberculosis and renal carcinoma.
(11) The qualification for carrying on the isonicotinic acid hydrazide monotherapy in the tuberculosis cutis luposa and verrucosa is proved on the basis of bacteriological, pathologo-anatomical and clinical peculiarities of these forms of tuberculosis of the skin.
(12) Approximately 16,000 people were diagnosed with multidrug-resistant tuberculosis in 2012 but were not given the treatment they needed to stay alive and prevent the spread of the disease, the World Health Organisation (WHO) has said.
(13) The risk of "Gesunde Befundträger" (healthy carriers of pulmonary lesions) to develop pulmonary tuberculosis is compared with that of persons with X-ray shadows in the lung.
(14) These findings are used to interpret published data from the chronic experimental murine tuberculosis model and support the view that in the mouse, the efficacy of RIF in widely spaced intermittent chemotherapy is the result of its long half-life.
(15) In tuberculosis this effect has been indirectly attributed to the production of cord factor (alpha,alpha-trehalose 6,6'-dimycolate).
(16) Twenty-two patients with radiologically localised pulmonary tuberculosis underwent one or more broncho-alveolar lavages: 10 patients had a single lavage in the disease area, 11 had two lavages (1 in a healthy zone and 1 in the affected zone) and 1 patient had a triple lavage.
(17) We concluded that IS986 is an extremely suitable tool for the diagnosis and epidemiology of tuberculosis.
(18) The in vitro susceptibility of Mycobacterium tuberculosis to a new macrolide antibiotic RU-28965, alone and in combination with rifampicin or isoniazid, was studied by the agar dilution method.
(19) Tuberculosis of the cervix of the uterus is a rare form of genital tuberculosis.
(20) However, a review of 103 cases of tuberculosis presenting to a general hospital showed that 53% of the patients did not have fever when they first came to the outpatient clinic, and 10% did not have fever at any time while under observation.