(n.) Loss sustained from failure to fulfill a bargain or contract.
(n.) Any morbid change in the exercise of functions or the texture of organs.
Example Sentences:
(1) The telencephalic proliferative response has been studied in adult newts after lesion on the central nervous system.
(2) To quantify the size of the lesion in mice, the area of the infarct on the brain surface was assessed planimetrically 48 h after MCA occlusion by transcardial perfusion of carbon black.
(3) An effective graft-surveillance protocol needs to be applicable to all patients; practical in terms of time, effort, and cost; reliable; and able to detect, grade, and assess progression of lesions.
(4) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(5) Weddellite calcification was associated with benign lesions in 16 cases, but incidental atypical lobular hyperplasia and lobular carcinoma in situ were present, each in one case.
(6) One must be suspicious of any gingival lesion, particulary if there is a sudden onset of bleeding or hyperplasia.
(7) The cross sectional area of the aortic lumen was gradually decreased while the length of the stenotic lesion gradually increased by using strips with different width.
(8) A total of 555 caries lesions were registered on proximal surfaces, 49.1% being primary lesions in the enamel, 21.4% primary lesions into the dentin and 29.5% secondary lesions.
(9) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(10) Pleural or subpleural lesions were found in all cases.
(11) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(12) The results also indicate that small lesions initially noted only on CT scans of the chest in children with Wilms' tumor frequently represent metastatic tumor.
(13) The lesion (10.6 X 9.8 mm) was a well-defined ellipsoid granuloma due to a foreign body with a central zone of necrosis surrounded entirely by a fibrous wall.
(14) Macroscopic lesions included mild congestion of the gastric mucosa and focal consolidation of the lung.
(15) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
(16) We report on a patient, with a CT-verified low density lesion in the right parietal area, who exhibited not only deficits in left conceptual space, but also in reading, writing, and the production of speech.
(17) Differentiation between these two types of lesions is of utmost importance since the surgical approach will be different.
(18) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
(19) In the present study, the expression of type IV collagen associated with the basal membrane (BM) was studied histochemically (indirect immunoperoxidase-antiperoxidase) in cervical human papillomavirus (HPV) lesions (diagnosed using in situ DNA hybridization) of different grades.
(20) Patients with sarcoidosis that present only cutaneous lesions are uncommon but have been described.
Pellagra
Definition:
(n.) An erythematous affection of the skin, with severe constitutional and nervous symptoms, endemic in Northern Italy.
Example Sentences:
(1) On the basis of that work Joseph Goldberger developed a diet which produced a condition analogous to pellagra in dogs.
(2) Pellagra diagnosis was made on the basis of the typical clinical skin picture, and low urinary excretion of N'methylnicotinamide and N'methyl-2-pyridone-5-carboxamide (reduced by 70 and 80%, respectively, compared with controls).
(3) These results suggest that Zn interacts with niacin metabolism in alcoholic patients with pellagra through a probable mediation by vitamin B-6.
(4) D-xylose absorption tests and jejunal morphology have been shown to be unaltered in 12 African patients with pellagra when compared with normal values for Zambian Africa adults; that result is contrary to two previous investigations in India and Egypt respectively.
(5) 231 cases of pellagra among 8,000 consulting patients has been observed from May 1977 to June 1978 in the Dermatological Dispensary of the Hospital G.E.C.A.-Mines of Lumbumbashi (Zaire).
(6) Two types of pathologic state are unquestionably the concern of vitaminotherapy: More or less specific and intense vitamin deficiencies: Rickets, scurvy, beri beri, pellagra, vitamin deficiency related to alcohol consumption, polyneuritis, encephalopathy, malabsorption, mucoviscidosis, etc.
(7) Pellagra is a classical disease rarely seen in this country.
(8) Pellagra in the human is characterized by the clinical "three D's," namely, dermatitis, diarrhea, and dementia.
(9) Dermatoses with photosensitivity are divided into three groups: photo-aggravated dermatoses (solar herpes, lupus erythematosus), photosensitivity caused by protective system defect (xeroderma pigmentosum), and photosensitivity caused by metabolic defects (porphyrias, pellagra).
(10) His CNS lesions were composed of disseminated necrotic foci in the cerebral cortices with many Alzheimer type II astrocytes, pachymeningitis hemorrhagica interna, and lesions similar to pellagra and Wernicke encephalopathy.
(11) The nicotinamide nucleotide concentrations in the erythrocytes of subjects suffering from pellagra (pellagrins) were not lower than those in normal subjects, but the ability of erythrocytes to synthesize these nucleotides in vitro was significantly lower in pellagrins.
(12) In pellagra, symmetric keratotic areas on the face are always accompanied by lesions elsewhere on the body.
(13) It is concluded that pellagra per se does not alter intestinal structure or monosaccharide absorption.
(14) It is noted that some of the manifestations of prolonged sleep deprivation are similar to changes seen in pellagra.
(15) We evaluated the effects of SMS 201-995 in 14 such patients, 12 with diarrhea, 8 with flushing, 3 with wheezing, one with tricuspid valve incompetence, 6 with facial telangiectasia, 3 with a pellagra type dermatosis and one with myopathy.
(16) Tryp deficiency caused classical manifestations of pellagra although niacin intake was in excess of normal requirements.
(17) The first symptom of the disease was a serious and prolonged pellagra-like photodermatitis.
(18) Photosensitivity has also been associated with pellagra.
(19) The condition manifests as a pellagra-like skin rash within 8 weeks after birth, with signs of cerebellar ataxia and developmental retardation.
(20) A patient who was treated with isoniazid and who developed pellagra is presented.