(n.) One who lets or permits; one who lets anything for hire.
(n.) One who retards or hinders.
(n.) A mark or character used as the representative of a sound, or of an articulation of the human organs of speech; a first element of written language.
(n.) A written or printed communication; a message expressed in intelligible characters on something adapted to conveyance, as paper, parchment, etc.; an epistle.
(n.) A writing; an inscription.
(n.) Verbal expression; literal statement or meaning; exact signification or requirement.
(n.) A single type; type, collectively; a style of type.
(n.) Learning; erudition; as, a man of letters.
(n.) A letter; an epistle.
(v. t.) To impress with letters; to mark with letters or words; as, a book gilt and lettered.
Example Sentences:
(1) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
(2) Accuracy of discrimination of letters at various preselected distances was determined each session while Ortho-rater examinations were given periodically throughout training.
(3) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.
(4) And, according to a letter leaked to the BBC last week , he reckons he has found one: default-on.
(5) Fry's letter was also delivered to the Lausanne headquarters of the International Olympic Committee, by Guillaume Bonnet of the campaign group All Out .
(6) It’s gender, age, disability, sexual orientation, social background, and – most important of all, as far as I’m concerned – diversity of thought.” Diversity needs action beyond the Oscars | Letters Read more He may have provided the Richard Littlejohn wishlist from hell – you know the one, about the one-legged black lesbian in a hijab favoured by the politically correct – but as a Hollywood A-lister, the joke’s no longer on him.
(7) We have much more fighting to do!” Now Cherwell is preparing to publish letters or articles from other students who have been inspired to open up about their own ordeals.
(8) The reported study demonstrates that performance asymmetries between normal or reflected letters presented in the right and left visual field favors the right visual field when stimulus patterns are blocked and rotated 90 degrees clockwise and favors the left visual field when they are blocked and rotated 90 degrees counterclockwise.
(9) The letters of discharge or the case records were obtained for all patients under one year for the entire period and for all patients over one year for the period 1984-1986, a total of 627 persons.
(10) But under Comey’s FBI, the agency has continued to disregard the justice department’s legal opinion, and to this day, demands tech companies hand it all sorts of data under due-process free National Security Letters.
(11) The letter to Florence Nightingale was written by Bernita Decker as part of a nursing course assignment for our Nurse Educator advisor, Betty Pugh.
(12) A letter Acosta received warned her of a Snap cut of $11 for each family member in November.
(13) However, the law minister indicated he would allow the supreme court to approve a draft of the letter.
(14) These letters are also written during a period when Joyce was still smarting from the publishing difficulties of his earlier works Dubliners and A Portrait of the Artist as a Young Man.” Gordon Bowker, Joyce’s biographer, agreed: “Joyce’s problem with the UK printers related to the fact that here in those days printers were as much at risk of prosecution on charges of publishing obscenities as were publishers, and would simply refuse to print them.
(15) The prime minister sent back a letter dismissing his allegations.
(16) She kept it up for three years, until her son's letters finally persuaded her to cut down to one day a week.
(17) The letter praised the company's progress in responding to the inspection.
(18) The letters, seen by Guardian Money, state that the French-owned company is conducting a review of customer records to make sure all its information is up to date.
(19) The day it opened in the US, three senators – senate select committee on intelligence chairwoman Dianne Feinstein, Carl Levin and John McCain – released a letter of protest to Sony Pictures's CEO, citing their committee's 6,000-page classified report on interrogation tactics and calling on him "to state that the role of torture in the hunt for Osama bin Laden is not based on the facts, but rather part of the film's fictional narrative".
(20) "Fifa received a letter via email and fax from the Costa Rica FA on March 24 with regards to the 2014 FIFA World Cup qualifier played on March 22 between USA and Costa Rica," Fifa said.
Primer
Definition:
(n.) One who, or that which, primes
(n.) an instrument or device for priming; esp., a cap, tube, or water containing percussion powder or other compound for igniting a charge of gunpowder.
(a.) First; original; primary.
(n.) Originally, a small prayer book for church service, containing the little office of the Virgin Mary; also, a work of elementary religious instruction.
(n.) A small elementary book for teaching children to read; a reading or spelling book for a beginner.
(n.) A kind of type, of which there are two species; one, called long primer, intermediate in size between bourgeois and small pica [see Long primer]; the other, called great primer, larger than pica.
Example Sentences:
(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) Elongation of existing RNA primers by the human polymerase-primase was semi-processive; following primer binding the DNA polymerase continuously incorporated 20 to 50 nucleotides, then it dissociated from the template DNA.
(3) This cDNA was obtained because of an identical 10 bp match with the 3' end of one of the GnRH primers.
(4) When PCR products in each of the 12 cats were subjected to a second amplification using the same primer pair (two-step amplification: double PCR), FIV proviral DNA was detected in all of the cats.
(5) In junctions, 3' PSS termini are preserved by fill-in DNA synthesis, although their 5' recessed ends cannot serve as a primer.
(6) Previous studies demonstrated that, when poly(dT).oligo(dA) was used as a template-primer, both proteins were required for poly(dA) synthesis.
(7) 5'-Ends of transcripts of the region were located by S1 nuclease mapping and primer extension.
(8) Nucleotide incorporation kinetics were determined and sequence specific pausing was analyzed by primer-extension.
(9) Primer extension and S1 nuclease protection analysis demonstrate that the hepatic and kidney specific mRNAs are transcriptionally initiated at different sites within the sialyltransferase gene.
(10) alpha 1 and alpha 2 were very similar as DNA polymerases in their sensitivity to several inhibitors and their preference for template-primers, except that alpha 1 had a slightly greater preference for poly (dT) X (rA)10 than alpha 2 did.
(11) Our results indicate that provirus expression occurs by two different mechanisms: one provirus acquired a single base pair mutation in the retrovirus tRNA primer binding site, permitting provirus expression; expression of three proviruses was mediated by 5'-flanking DNA sequences.
(12) Cognate sites in genomes that diverged approximately 100 million years ago can be detected by PCR assays based on primer pairs from unique sequences.
(13) HDV cDNA was then directly amplified with Taq polymerase using three pairs of specific primers.
(14) This reaction involved the synthesis of a short oligoribonucleotide primer which was then extended into a DNA chain.
(15) cDNA was prepared by reverse transcription of peripheral blood mRNA and amplified by the polymerase chain reaction (PCR) using primers corresponding to sequences 400 bp apart on the cDNA, spanning the last three exons (X, Y, Z) of the beta-Sp gene.
(16) B.subtilis phage M2 uses a protein, instead of RNA, as the primer of its DNA replication.
(17) Optimum specific amplification resulted when the primer annealing temperature was 60 degrees C. The gene fragment was amplifiable in 25 different Brucella species and strains.
(18) Primer extension experiments show that in fission yeast transcripts are initiated at the same starting point as in tomato, indicating for the first time that a plant promoter can be correctly recognized in fission yeast.
(19) Genomic clones for the mouse estrogen receptor have been isolated from a cosmid library and used in conjunction with the cDNA clones to study the expression of the receptor in vivo by RNase mapping, primer extension, and Northern blotting.
(20) By using primer 1 (5'-AAAGAATTCATGGAATCCAGGATCTG-3', upstream nucleotides 157 to 2877), primer 2 (5'-AAAGAATTCATGAACGTGAAGGAATCG-3', upstream nucleotides 1846 to 2877), and primer 4(5'-ATAAAGCTTAATCAGACGTTCTCTTCTTC-3', downstream nucleotides 157 to 2877 and 1846 to 2877), the HCMV B gene code region sequence and its glycoprotein 52 kd antigenic domain sequence were amplified from the recombinant plasmid pBH1 DNA containing the HCMV B gene.