(n.) A line or surface to which, at every point, a vertical or plumb line is perpendicular; a line or surface which is everywhere parallel to the surface of still water; -- this is the true level, and is a curve or surface in which all points are equally distant from the center of the earth, or rather would be so if the earth were an exact sphere.
(n.) A horizontal line or plane; that is, a straight line or a plane which is tangent to a true level at a given point and hence parallel to the horizon at that point; -- this is the apparent level at the given point.
(n.) An approximately horizontal line or surface at a certain degree of altitude, or distance from the center of the earth; as, to climb from the level of the coast to the level of the plateau and then descend to the level of the valley or of the sea.
(n.) Hence, figuratively, a certain position, rank, standard, degree, quality, character, etc., conceived of as in one of several planes of different elevation.
(n.) A uniform or average height; a normal plane or altitude; a condition conformable to natural law or which will secure a level surface; as, moving fluids seek a level.
(n.) An instrument by which to find a horizontal line, or adjust something with reference to a horizontal line.
(n.) A measurement of the difference of altitude of two points, by means of a level; as, to take a level.
(n.) A horizontal passage, drift, or adit, in a mine.
(a.) Even; flat; having no part higher than another; having, or conforming to, the curvature which belongs to the undisturbed liquid parts of the earth's surface; as, a level field; level ground; the level surface of a pond or lake.
(a.) Coinciding or parallel with the plane of the horizon; horizontal; as, the telescope is now level.
(a.) Even with anything else; of the same height; on the same line or plane; on the same footing; of equal importance; -- followed by with, sometimes by to.
(a.) Straightforward; direct; clear; open.
(a.) Well balanced; even; just; steady; impartial; as, a level head; a level understanding. [Colloq.]
(a.) Of even tone; without rising or falling inflection.
(v. t.) To make level; to make horizontal; to bring to the condition of a level line or surface; hence, to make flat or even; as, to level a road, a walk, or a garden.
(v. t.) To bring to a lower level; to overthrow; to topple down; to reduce to a flat surface; to lower.
(v. t.) To bring to a horizontal position, as a gun; hence, to point in taking aim; to aim; to direct.
(v. t.) Figuratively, to bring to a common level or plane, in respect of rank, condition, character, privilege, etc.; as, to level all the ranks and conditions of men.
(v. t.) To adjust or adapt to a certain level; as, to level remarks to the capacity of children.
(v. i.) To be level; to be on a level with, or on an equality with, something; hence, to accord; to agree; to suit.
(v. i.) To aim a gun, spear, etc., horizontally; hence, to aim or point a weapon in direct line with the mark; fig., to direct the eye, mind, or effort, directly to an object.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(3) Multiple stored energy levels were randomly tested and the percent successful defibrillation was plotted against the stored energy, and the raw data were fit by logistic regression.
(4) Serum levels of both dihydralazine and metabolites were very low and particularly below the detection limit.
(5) Carbon dioxide (CO2) levels, volumes, and temperatures of expired gas were measured from the tracheal and esophageal tubes.
(6) Since fingernail creatinine (Ncr) reflects serum creatinine (Scr) at the time of nail formation, it has been suggested that Ncr level might represent that of Scr around 4 months previously.
(7) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(8) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(9) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(10) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
(11) On the other hand, the LAP level, identical in preterms and SDB, is lower than in full-term infants but higher than in adults.
(12) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(13) Together these results suggest that IVC may operate as a selective activator of calpain both in the cytosol and at the membrane level; in the latter case in synergism with the activation induced by association of the proteinase to the cell membrane.
(14) Participants (n=165) entering a week-long outpatient education program completed a protocol measuring self-care patterns, glycosylated hemoglobin levels, and emotional well-being.
(15) Measurement of the intraspinal monoamine level revealed a decrease in the intraspinal norepinephrine level in the treated animals.
(16) The level of gadd45 mRNA increased rapidly after X rays at doses as low as 2 Gy.
(17) Irrespective of the type of arthropathy, synovial fluid dialysable hydroxyproline levels correlate with urinary hydroxyproline excretion.
(18) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(19) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(20) This new observation offers good possibilities to study the metabolism of tryptophan at the cellular level.
Notch
Definition:
(n.) A hollow cut in anything; a nick; an indentation.
(n.) A narrow passage between two elevation; a deep, close pass; a defile; as, the notch of a mountain.
(v. t.) To cut or make notches in ; to indent; also, to score by notches; as, to notch a stick.
(v. t.) To fit the notch of (an arrow) to the string.
Example Sentences:
(1) The Notch locus in Drosophila encodes a transmembrane protein required for the determination of cell fate in ectodermal cells.
(2) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
(3) For histometric evaluation, the radicular notches were used as reference points.
(4) Conversely, in 66 of 80 pregnancies the absence of a notch was associated with the livebirth of an infant beyond 32 weeks gestation, with a birthweight above the 5th centile.
(5) The left subclavian artery was prominent in 33 cases, signs indicating a collateral circulation (rib notching, internal mammary artery) were present in 26 cases.
(6) Notched tympanograms were typical of neonatal ears for a 220-Hz probe tone.
(7) Radiographic manifestations include endosteal sclerosis of the neurocranium with loss of the diploë, osteosclerosis and hyperostosis of the mandible with absence of the normal antegonial notches, endosteal sclerosis of the diaphyses of long bones (including metacarpals and metatarsals), and osteosclerosis of the pelvis.
(8) For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring.
(9) Lymphadenopathies were classified by the criteria proposed by Yoshinaka et al., type I: poorly-defined borders, diffuse internal echoes; type II: well-defined borders, diffuse internal echoes; type III: well-defined borders, notchings, strong internal echoes.
(10) Here, we examine a group of six recessive mutations, the facets (fa, fa3, fag, fag-2, fafx and fasw), which affect eye and optic lobe morphology and have been previously shown to be associated with the insertion of transposable elements into an intronic region of Notch.
(11) Another frequent finding was partial or total obstruction at the tentorial notch, often in combination with reduced or absent activity along the superior sagittal sinus.
(12) In one patient, the fibrous band extended from the distal pole of the patella to the intracondylar notch, tethering the patella inferiorly.
(13) This thin flap, usually extending from the hyoid bone to the sternal notch at the central part of the anterior neck, provides a skin island of about 4 by 8 cm.
(14) The chest roentgenographic findings in Takayasu's arteritis include widening of the ascending aorta, contour irregularities of the descending aorta, arotic calcifications, pulmonary arterial changes, rib notching, and hilar lymphadenopathy.
(15) In two cases the epidermoid, located mainly in the cerebello-pontine angle, spread into the middle cranial fossa; in three the epidermoid extended from the parasellar cisterns to the posterior cranial fossa; in six patients the epidermoid, enlarging the tentorial notch, occupied extensively both cranial fossae.
(16) This post-transcriptional regulation is suppressed in embryos mutant for the genes Notch and Delta; where all cells expressing RNA accumulate protein.
(17) The femoral intercondylar notch width was measured in 93 patients with chronic anterior cruciate ligament (ACL) insufficiency (Group 1), in 62 patients with an acute tear of the ACL (Group 2), and in 38 fresh anatomic specimen knees (Group 3).
(18) Deep notch cases had more retrusive mandibles with a shorter corpus, smaller ramus height, and a greater gonial angle than did shallow notch cases.
(19) The acicular alpha structure has been shown to exhibit the best fatigue properties for Ti-6A1-4V alloy in the notched condition.
(20) The anatomical relations of the semilunar notch of the ulna were studied in radiographs, taken in a strict lateral view, from 100 patients with elbow dislocations.