(1) These results suggest that signal transduction pathways for IL2 and IL3 involve tyrosine phosphorylation of protein substrates common to both lymphoid and myeloid linages.
(2) Binding of Bestatin to cells in the histiocytic linage upregulates colony stimulating activity (both in vitro and in vivo), which subsequently increases hematopoietic and hematologic values.
Linkage
Definition:
(n.) The act of linking; the state of being linked; also, a system of links.
(n.) Manner of linking or of being linked; -- said of the union of atoms or radicals in the molecule.
(n.) A system of straight lines or bars, fastened together by joints, and having certain of their points fixed in a plane. It is used to describe straight lines and curves in the plane.
Example Sentences:
(1) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
(2) Twelve families with Wiskott-Aldrich syndrome (WAS) were studied by linkage analysis using 10 polymorphic marker loci from the X-chromosome pericentromeric region.
(3) A complex linkage between the cytoskeleton and the extracellular matrix is illustrated both in the cord forming Sertoli and granulosa cells, and in the adjacent mesenchymal cells.
(4) The assumption was also corroborated using reagents from a family in which DR3 and DQw2 were not found in the usually described linkage.
(5) This linkage information was used to design complementation tests to determine allelism with previously characterized complementation groups affecting sensitivity to radiation.
(6) Sensitivity and specificity were enhanced when we linked multiple predictors, but this linkage was seldom successful because few patients had more than one positive predictor.
(7) Analysis of the product by equilibrium density centrifugation and processive hydrolysis with snake venom phosphodiesterase suggested that the noncomplementary nucleotides were present in phosphodiester linkage.
(8) The same segments have been described to be responsible for the hexamer-hexamer linkage (Yu, M.-H. & Glazer, A.N.
(9) The two disorders may associate within families through genetic linkage or a failure of neurotransmitter homoeostasis.
(10) Isopycnic analyses of the ribonucleotide initiated fd DNA replication products demonstrated covalent linkage between the initiator RNA and newly synthesized DNA.
(11) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
(12) Absence of linkage in a large group of families shows that lamp genes are not involved in Salla disease.
(13) Because each linkage project is different, the modular nature of the software allows for better control of the programming process and development of unique strategies.
(14) Family clustering suggests a genetic pathogenesis, but linkage to HLA or other blood group markers has not been found.
(15) Biosynthesis of the two N-glycosyl linkage units involves dolichol monophosphate and dolicholdiphosphate-linked saccharide precursors.
(16) In addition, the distances between markers in the mouse and human were similar except for one region of the conserved linkage group where we could detect a larger distance in the mouse compared to the human.
(17) The inter-connecting linkage system develops postnatally, and the 'tip-linkages' are already found in one-week-old mice, suggesting that the critical organization of the micromechanics of the stereocilia matures rapidly during the postnatal period.
(18) Using molecular probes to examine somatic cell lines and recombinant inbred and congenic strains of mice, we have re-evaluated these linkage relationships.
(19) We now report linkage between CF and pJ3.11 (Z = 4.92, theta = 0) and between CF and 7C22 (Z = 3.42, theta = 0).
(20) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).