(1) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(2) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
(3) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(4) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(5) The predicted non-Lorentzian line shapes and widths were found to be in good agreement with experimental results, indicating that the local orientational order (called "packing" by many workers) in the bilayers of small vesicles and in multilamellar membranes is substantially the same.
(6) On the other hand, human IL-9, which is a homologue to murine P40, was cloned from a cDNA library prepared with mRNA isolated from PHA-induced T-cell line (C5MJ2).
(7) However, four of ten young adult outer arm (relatively sun-exposed) and one of ten young adult inner arm (relatively sun-protected) fibroblasts lines increased their saturation density in response to retinoic acid.
(8) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(9) In contrast to L2 and L3 in L1 the mid gut runs down in a straight line without any looping.
(10) In addition, KM231 could detect a small amount of the antigen ganglioside in human gastric normal and cancerous mucosa and in gastric cancer cell lines by HPTLC-immunostaining.
(11) Taken together these results are consistent with the view that primary CTL, as well as long term cloned CTL cell lines, exercise their cytolytic activity by means of perforin.
(12) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(13) The aetiological factors concerned in the production of paraumbilical and epigastric hernias have been reviewed along structural--functional lines.
(14) The antiproliferative activity of IFN was studied using the parental L cell line, a tk- derivative, and a tk- (tk+) subline into which the tk gene of herpes simplex virus was introduced.
(15) A murine keratinocyte cell line that is resistant to the growth-inhibitory effects of transforming growth factor beta 1 (TGF beta 1) was examined for differential gene expression patterns that may be related to the mechanism of the loss of TGF beta 1 responsiveness.
(16) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
(17) Cell lines specific for class I or class II loci of the MHC produced interferon and colony-stimulating factors.
(18) Seven patients were treated with combination chemotherapy, consisting of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) or MOPP (chloromethine, vincristine, procarbazine, prednisone), in some cases followed by non-cross-resistant second line chemotherapy, if no complete response was attained.
(19) Displacement of a colinear line over the same range without an offset evoked little, if any, response.
(20) N-Ethylmaleimide-sensitive 5'-nucleotide phosphodiesterase and alkaline phosphatase activities from other cell lines were also recovered in the cytosol.
Wrinkle
Definition:
(n.) A winkle.
(n.) A small ridge, prominence, or furrow formed by the shrinking or contraction of any smooth substance; a corrugation; a crease; a slight fold; as, wrinkle in the skin; a wrinkle in cloth.
(n.) hence, any roughness; unevenness.
(n.) A notion or fancy; a whim; as, to have a new wrinkle.
(v. t.) To contract into furrows and prominences; to make a wrinkle or wrinkles in; to corrugate; as, wrinkle the skin or the brow.
(v. t.) Hence, to make rough or uneven in any way.
(v. i.) To shrink into furrows and ridges.
Example Sentences:
(1) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(2) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(3) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(4) In fact, in some patients the lower-lid wrinkling appears far worse after fat removal.
(5) Substratum wrinkling was indicative of tension development and quantitated as percent of cells contracted.
(6) SMC also displayed several structurally detectable interactions with the fibrin substratum, such as organization of the gel by means of extension of numerous filamentous processes and contraction and wrinkling of the gel.
(7) A recipient cornea gradually developed wrinkling and opacification in Bowman's layer following an uneventful myopic epikeratoplasty.
(8) "But then a customer pointed out that our carpet was smoking and a chair was beginning to wrinkle in the heat, caused by the concentrated sun coming through the window."
(9) More than once, she replies to a question by wrinkling her nose and saying: “It’s all in the book.” Tempest can’t quite see why the breadth of her output – songs, poems, plays, a novel – is notable, because it’s all about writing and performance.
(10) Some intercalated sheaths had a wrinkled irregular configuration and some lacked a light-microscopically distinct myelin layer.
(11) Adhesions to the Gore-SM occurred at wrinkles in or at the edges of the membrane.
(12) During the course of the irradiation the animals develop permanent wrinkles on the exposed dorsal surface, which can be recorded in plastic impressions.
(13) The deflecting wrinkle is a well-known character state of the lower m2 and M1 of the human dentition, but there is little information regarding its presence in great apes.
(14) An algorithm is used to transform the number of wrinkles, recorded just before and 2.5 and 6 hr after the injection, into the intensity of the oedematous reaction.
(15) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(16) Kaeng Khoi virus was recovered from bedbugs (Stricticimex parvus and Cimex insuetus) and from suckling wrinkle-lipped bats (Tadarida plicata) collected in central Thailand.
(17) Hacked Off, which campaigns on behalf of victims of press intrusion for tighter press regulation, said this would help the government smooth out the wrinkles in the relevant clause added to the crime and courts bill, which attempts to define which publishers should be in or outside the regulator's remit.
(18) The percentage of cells showing a decrease of wrinkles was significantly higher (P less than 0.05 at 5 min and P less than 0.001 at 10 min) during the ANP-treated period than during the control period.
(19) Most dogs give a series of increasingly serious warning signs before they lose their tempers: lick their lips, blink, turn their heads away, curl their lip, lower their ears, wrinkle their foreheads, and if the dog that's annoying them doesn't get the message, they may growl or bare their teeth, and if that's still not enough it will be head and chest forward, muscles flexed, and bang, you've had it.
(20) Other specimens showed wrinkling of the outer layer that was seen later to peel off.