(n.) The act of linking; the state of being linked; also, a system of links.
(n.) Manner of linking or of being linked; -- said of the union of atoms or radicals in the molecule.
(n.) A system of straight lines or bars, fastened together by joints, and having certain of their points fixed in a plane. It is used to describe straight lines and curves in the plane.
Example Sentences:
(1) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
(2) Twelve families with Wiskott-Aldrich syndrome (WAS) were studied by linkage analysis using 10 polymorphic marker loci from the X-chromosome pericentromeric region.
(3) A complex linkage between the cytoskeleton and the extracellular matrix is illustrated both in the cord forming Sertoli and granulosa cells, and in the adjacent mesenchymal cells.
(4) The assumption was also corroborated using reagents from a family in which DR3 and DQw2 were not found in the usually described linkage.
(5) This linkage information was used to design complementation tests to determine allelism with previously characterized complementation groups affecting sensitivity to radiation.
(6) Sensitivity and specificity were enhanced when we linked multiple predictors, but this linkage was seldom successful because few patients had more than one positive predictor.
(7) Analysis of the product by equilibrium density centrifugation and processive hydrolysis with snake venom phosphodiesterase suggested that the noncomplementary nucleotides were present in phosphodiester linkage.
(8) The same segments have been described to be responsible for the hexamer-hexamer linkage (Yu, M.-H. & Glazer, A.N.
(9) The two disorders may associate within families through genetic linkage or a failure of neurotransmitter homoeostasis.
(10) Isopycnic analyses of the ribonucleotide initiated fd DNA replication products demonstrated covalent linkage between the initiator RNA and newly synthesized DNA.
(11) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
(12) Absence of linkage in a large group of families shows that lamp genes are not involved in Salla disease.
(13) Because each linkage project is different, the modular nature of the software allows for better control of the programming process and development of unique strategies.
(14) Family clustering suggests a genetic pathogenesis, but linkage to HLA or other blood group markers has not been found.
(15) Biosynthesis of the two N-glycosyl linkage units involves dolichol monophosphate and dolicholdiphosphate-linked saccharide precursors.
(16) In addition, the distances between markers in the mouse and human were similar except for one region of the conserved linkage group where we could detect a larger distance in the mouse compared to the human.
(17) The inter-connecting linkage system develops postnatally, and the 'tip-linkages' are already found in one-week-old mice, suggesting that the critical organization of the micromechanics of the stereocilia matures rapidly during the postnatal period.
(18) Using molecular probes to examine somatic cell lines and recombinant inbred and congenic strains of mice, we have re-evaluated these linkage relationships.
(19) We now report linkage between CF and pJ3.11 (Z = 4.92, theta = 0) and between CF and 7C22 (Z = 3.42, theta = 0).
(20) Recently, a gene for ITD (DYT1) in a non-Jewish kindred was located on chromosome 9q32-34, with tight linkage to the gene encoding gelsolin (GSN).
Recombination
Definition:
(n.) Combination a second or additional time.
Example Sentences:
(1) We were able to detect genetic recombination between vaccine strains of PRV following in vitro or in vivo coinoculation of 2 strains of PRV.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
(4) To determine whether or not the glycan moieties in hTPO play a role in the disease-associated epitopes in Hashimoto's thyroiditis, radiolabeled recombinant hTPO was immunoprecipitated after digestion with N-glycanase.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Preincubation of human neutrophils with recombinant tumor necrosis factor alpha has previously been shown by us to enhance superoxide production of neutrophils in response to the chemotactic peptide formyl-methionyl-leucyl-phenylalanine, and the phorbol ester, phorbol myristate acetate.
(7) The relative potencies compared to insulin-like growth factor 2 (IGF-2) in displacing [125I]IGF-2 from rat liver membranes were recombinant truncated IGF-1, 0.3% and recombinant IGF-1, 0.2%.
(8) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
(9) Conjugational recombination in Escherichia coli was investigated by monitoring synthesis of the lacZ+ product, beta-galactosidase, in crosses between lacZ mutants.
(10) To augment the in vitro expansion of LAK cells, we added highly purified human recombinant interleukin-2, phytohemagglutinin and accessory cells (Uc cells) to the LAK culture system, with which huge number of LAK cells (LAK-L) were generated from originally small number of peripheral blood lymphocytes of cancer patients.
(11) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(12) The coding sequence for Spirulina platensis acetohydroxy acid synthase (AHAS, EC 4.1.3.18) is shown to be contained within a 4.2 Kb ClaI fragment (ilvX) that has been cloned from a recombinant lambda library.
(13) The yield of the process is also shown to be particularly dependent on the recombinant protein concentration.
(14) Analysis of genetic markers associated with the deleted haplotypes pointed to the independent origin of similar deletions and the involvement of intergenic sequences in the mispairing-recombination process.
(15) Unlike unattenuated virus, the Us3::pgC-lacZ recombinant caused little apparent damage to normal hippocampal morphology.
(16) Immunogenic or pathogenic factors of recombinant proteins (rBCSP20, rBCSP-31, and rBCSP45 of Brucella abortus strain 19) for mice were compared with factors of a proteinase K-treated lipopolysaccharide extracted from B abortus strain 2308.
(17) The majority of the recombinants had received all the other gene segments from the sensitive parent strain.
(18) When CO was photolytically dissociated from the reduced protein two recombination processes were observed with rates almost identical with those observed in the stopped-flow experiments (k+1 = 3.3 X 10(3)M-1-S-1 and k+2 = 6.0 X 10(2)M-1-S-1).
(19) In 130 patients, who were considered to be anti-HTLV-I positive or negative by the PA method, we compared the anti-HTLV-I detection rates and the specificity of the following three EIA methods: the Ei-test ATL and two new EIA methods using different recombinant antigens which recognize different sites.
(20) Neurospora crassa mitochondrial deoxyribonucleic acid shows strict uniparental inheritance in sexual crosses, with a notable absence of mixtures and recombinant types that appear frequently in heteroplasmons.