(v.) A burden; that which is laid on or put in anything for conveyance; that which is borne or sustained; a weight; as, a heavy load.
(v.) The quantity which can be carried or drawn in some specified way; the contents of a cart, barrow, or vessel; that which will constitute a cargo; lading.
(v.) That which burdens, oppresses, or grieves the mind or spirits; as, a load of care.
(v.) A particular measure for certain articles, being as much as may be carried at one time by the conveyance commonly used for the article measured; as, a load of wood; a load of hay; specifically, five quarters.
(v.) The charge of a firearm; as, a load of powder.
(v.) Weight or violence of blows.
(v.) The work done by a steam engine or other prime mover when working.
(v. t.) To lay a load or burden on or in, as on a horse or in a cart; to charge with a load, as a gun; to furnish with a lading or cargo, as a ship; hence, to add weight to, so as to oppress or embarrass; to heap upon.
(v. t.) To adulterate or drug; as, to load wine.
(v. t.) To magnetize.
Example Sentences:
(1) After a period on fat-rich diet the patient's physical fitness was increased and the recovery period after the acute load was shorter.
(2) The only sign of life was excavators loading trees on to barges to take to pulp mills.
(3) Spermine clearly activated 45Ca uptake by coupled mitochondria, but had no effect on Ca2+ egress from mitochondria previously loaded with 45Ca.
(4) In the case of nonspecific loading highly trained individuals may have low VT values close to the level characteristic for normal subjects.
(5) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(6) Excretion of inactive kallikrein again correlated with urine flow rate but the regression relationship between the two variables was different for water-load-induced and frusemide-induced diuresis.
(7) With this system, a brain region loaded with fura-2 was illuminated by a rotating disc bearing three different interference filters of 340, 360 and 380 nm at a rate of 600 rpm.
(8) Eddy current transducers measured relative displacements under application of static loads, serially applied in the axial, mediolateral, and craniocaudal directions.
(9) Over the course of 26-40 h the Na- and water-loaded cells returned to a normal state of hydration as judged by their density.
(10) Subjects who trained an additional 52 wk showed a slight drop in SV at submaximal work loads from the initial increase following the first 9 wk.
(11) For the non-emergency admissions, the low-load physicians' patients had an average LOS that was 56.2% greater and an average hospital cost that was 58.3% greater than were the LOS and cost of the patients of the high-load physicians.
(12) The presence of an inverse correlation between certain tryptophan metabolites, shown previously to be bladder carcinogens, and the N-nitrosamine content, especially after loading, was interpreted in view of the possible conversion of some tryptophan metabolites into N-nitrosamines either under endovesical conditions or during the execution of the colorimetric determination of these compounds.
(13) The effects of supervised mild aerobic exercise at the work load of the blood lactate threshold for 10 weeks on serum lipids and apolipoproteins were studied in 24 patients with essential hypertension.
(14) In the water-loaded state, MAP rose significantly at the lowest rate of infusion in both pregnant and non-pregnant ewes.
(15) Respiratory muscle endurance at a given level of load was assessed from the time of exhaustion and from the time course of the change in the power spectrum (centroid frequency) of the diaphragm electromyogram (EMG).
(16) Regressional analysis of relations between loads and the level of inbreeding in the Adyg population showed the explicit interrelation between the load of autosomal-dominant diseases and the Fst correlation coefficient being 0.89.
(17) 9 Women performed plantarflexion and dorsalflexion with maximum strength and at constant load of 60% MVC to exhaustion.
(18) In PSS amiloride and EIPA each had a small inhibitory effect on the pH recovery after an acid load.
(19) Also blacks differ from whites in 2 ways that could be relevant for their increased prevalence of hypertension: they excrete sodium loads more slowly and have a markedly lower urinary kallikrein.
(20) Calcium loading to erythrocytes in vitro caused a greater decrease in the membrane fluidity in essential hypertension than in the normotensive controls.
Overload
Definition:
(v. t.) To load or fill to excess; to load too heavily.
(n.) An excessive load; the excess beyond a proper load.
Example Sentences:
(1) By means of rapid planar Hill type antimony-bismuth thermophiles the initial heat liberated by papillary muscles was measured synchronously with developed tension for control (C), pressure-overload (GOP), and hypothyrotic (PTU) rat myocardium (chronic experiments) and after application of 10(-6) M isoproterenol or 200 10(-6) M UDCG-115.
(2) In iron-overloaded patients with primary haemochromatosis, there was inappropriately high uptake of iron by the biopsy specimens.
(3) The patient presented urgently for Caesarean section, with fluid overload and worsening thrombocytopaenia.
(4) Al hepatocytes overload appeared only in nuclei and not in nuclei and not in lysosomes, contrarily to chronic intoxications.
(5) Fluid overload, which could have been caused by the hyperosmolar properties of dextran, worsened progressively as fluids were drawn from the interstitial space and urine output was reduced.
(6) There were no significant differences between the mean levels of peak blood pressures (systolic, diastolic and mean), degree of fluid overload, and fractional sodium excretion in the 2 groups.
(7) Persisting diastolic dysfunction with a substantial rise in left ventricular filling pressure can be observed during dynamic exercise in postoperative patients with preoperative severe pressure overload hypertrophy.
(8) The 8 men and 3 women were clinically stable, were known to be compliant, and had no clinical evidence of aluminum overload; they were not receiving vitamin D supplements; and they had been on dialysis for an average of 65.6 months (range: 13-188 months).
(9) Wilson disease is due to a genetically determined impairment of copper excretion from liver into bile resulting in copper overload of the organism.
(10) There was no change in the sarcolemmal Mg2+ -ATPase of the left or right ventricle for the whole duration (3 to 9 months) of left ventricular pressure overload.
(11) These experimental results demonstrate that aluminium interferes with iron absorption and iron transfer, and suggest that these mechanisms may be responsible for maintaining and even increasing the anaemia observed in aluminium overload.
(12) When a high dose of the complex was administered, an overloading with hemosiderin of macrophages and hepatocytes was noticed.
(13) The subsequent accumulation of Na+ in the cell Na(+)-Ca2+ exchange, which can ultimately result in intracellular Ca2+ overload, contractile dysfunction and damage.
(14) If overloaded, these areas are subject to "cervical cratering," a common prelude to implant failure.
(15) The rationale for the inclusion of Mg in cardioplegic solutions therefore lies not in its cardioplegic properties, but in its ability to influence other cellular events such as the loss of Mg and K and perhaps to counter the detrimental effects of ischemia by antagonizing calcium (Ca) overload.
(16) Cardiac hypertrophy due to a chronic hemodynamic overload is accompanied by isoformic changes of two proteins of the thick filament of the sarcomere, myosin, and creatine phosphokinase.
(17) Age, gender and laboratory markers of iron overload did not differentiate patients with cardiac dysfunction (group 1) from those without cardiac dysfunction (group 2).
(18) Severe overloading can increase microdamage alarmingly, its repair by BMUs too, and can cause woven bone formation, anarchic resorption and a regional acceleratory phenomenon.
(19) Thus, it appears that the increased expression of the regulatory MLC2 gene in SHR atrial cells is a predetermined event, which, most likely, participates in functional adaptation of the myocardium in response to pressure overload and subsequent hypertrophy.
(20) To help resolve the issue of contractile function in volume overload hypertrophy, we examined ventricular function in a recently described model of severe chronic experimental mitral regurgitation.