(n.) A contraction of the muscles of the jaw by which its motion is suspended; a variety of tetanus.
Example Sentences:
(1) Several years' observations with the muscle relaxant Mydeton (150 mg coated tablet) in the treatment of lockjaw of different etiology have been discussed.
(2) All of these patients with tetanus on admission showed typical features, with the most common initial complaints being lockjaw and dysphagia (82.6%).
(3) Keep Belfast festive I watched ’71, Yann Demange’s thriller about a British soldier stranded in the streets of Troubles-era Belfast, with a mixture of lockjaw tension and vague recognition.
(4) The tumor had created a fusion with the ipsilateral coronoid process of the mandible, thus causing lockjaw.
(5) Like the purified defibrinating fraction("Arvin") of the venom of the Malayan pit viper (Agkistrodon rehodostoma), which is currently being used and evaluated as an anticoagulant, the thereapeutic possibilities of a purified neurotoxin that could produce a flaccid paralysis lasting two days or more were anticipated well before 1891 by Lauterer, who, as a result of his experiments, "injected viper poison...under the skin of a boy suffering from tentanus treaumaticus (lockjaw) and slackened the muscles of the whole body by it."
(6) Edward Fox is something of a Flemingesque dreamboat, with his flaxen locks, his aristocratic lockjaw and his subaltern's bearing (I imagine Fox as Freddie Forsyth's idealised version of himself ).
Tetanus
Definition:
(n.) A painful and usually fatal disease, resulting generally from a wound, and having as its principal symptom persistent spasm of the voluntary muscles. When the muscles of the lower jaw are affected, it is called locked-jaw, or lickjaw, and it takes various names from the various incurvations of the body resulting from the spasm.
(n.) That condition of a muscle in which it is in a state of continued vibratory contraction, as when stimulated by a series of induction shocks.
Example Sentences:
(1) Twitch-tetanus ratios were calculated and found not to be related to unit contraction time.6.
(2) The combination vaccine consisted of 12 Lf tetanus toxoid and 10 TCID50 vaccinia virus "MVA" preserved with gelatine and glucosamine.
(3) An analysis of 249 cases of neontal tetanus admitted to Korle-Bu Teaching Hospital, Accra, between January 1971 and December 1974, has been presented.
(4) The stiffness of the fibre first rose abruptly in response to stretch and then started to decrease linearly while the stretch went on; after the completion of stretch the stiffness decreased towards a steady value which was equal to that during the isometric tetanus at the same sarcomere length, indicating that the enhancement of isometric force is associated with decreased stiffness.
(5) Between 1974 and 1984, 418 patients with tetanus, aged 10 years and older, represented 64.8% of all admissions to the intensive care unit of the Lagos University Teaching Hospital.
(6) Neither the two-chain forms of botulinum A toxin and tetanus toxin, under reducing conditions, nor the light chains of tetanus toxin, inhibited amylase release triggered by Ca2+, or combinations of Ca2+ + GTP[S] or Ca2+ + cAMP.
(7) The only significant change found was in the radioactivity of the 18,000-dalton light chain of myosin; during a single tetanus, an increase of 85 to 90% occurred as compared to the resting muscle.
(8) In this report, we describe the successful generation of triomas secreting HuMAbs to tetanus toxin (tt).
(9) In DA-depleted slices, LTD could be restored by applying exogenous DA (30 microM) before the conditioning tetanus.
(10) Different components of B. pertussis were found to have a similar inhibitory effect on thymidine-3H incorporation caused by phytohemagglutinin (PHA) in the culture of lymphocytes taken from donors immunized with tetanus toxoid.
(11) Two main polypeptides, Mr about 27,000 and 21,000, were protected against pepsin proteolysis when a mixture consisting of asolectin vesicles and 125I-labeled tetanus toxin was subjected to a pH drop from 7.2 to 3.0.
(12) Enzyme-linked immunosorbent assay (ELISA) tests were developed to detect IgG antibodies to diphtheria, tetanus, and pertussis in a healthy New Zealand population.
(13) The tetanus antitoxin titers of blood obtained by venepuncture and those of finger-blood absorbed on filter paper are compared when the titration techniques use fresh or formalinized erythrocytes sensitized by the bis-diazotized benzidine (BDB) method.
(14) Because previous studies assumed that tetanus is an acetylcholine intoxication, atropine as a potent anticholinergic agent has been employed as a continuous infusion in the treatment of 4 severe tetanus cases as a supplement to routine therapy.
(15) Secondary structure contents of tetanus neurotoxin have been estimated at neutral and acidic pH using circular dichroism (CD) and Fourier transform infrared (FT-IR) spectroscopy.
(16) In regular medicine if a patient goes to a doctor to be treated for a rat bite, the physician cleans the bite, dresses it, gives antibiotics, and gives a tetanus shot.
(17) These findings are in accordance with the immunization programme followed for prophylaxis against tetanus among pregnant women.
(18) AMP aminohydrolase activity is enhanced by 60% after 5 s tetanic stimulation of phosphorylase kinase-deficient mouse muscle and after 60 s tetanus in normal mice.
(19) Fragment C is a non-toxic 50 kDa fragment of tetanus toxin which is a candidate subunit vaccine against tetanus.
(20) Data are presented to show that the adoption of such methods would increase the information available from each animal and so reduce the number of animals required for the satisfactory standardization of diphtheria and tetanus vaccines.