(adv.) A direction in written or printed music to return to the proper pitch after having played an octave higher.
(n.) A plant (Astragalus Hornii) growing in the Southwestern United States, which is said to poison horses and cattle, first making them insane. The name is also given vaguely to several other species of the same genus. Called also loco weed.
Example Sentences:
(1) Staplers were used and therefore the choice between resection or amputation was determined by the degree of loco-regional infiltration of the neoplasm.
(2) No patient developed metastases without previous clinically-evident invasive loco-regional disease.
(3) It is of mechanical or mixed type, accompanied by local, pseudo-inflammatory signs being either apparent or discrete, very elective and very sharp pain upon palpation of a very limited area of a condyle or a tibial plate, with hyperfixation located through scintigraphy with technetium 99m polyphosphates, and regressing either spontaneously, or more quickly under treatment, of which thyrocalcitone is the essential part, without undergoing a phase of intense loco-regional demineralization.
(4) There was complete loco-regional tumour control in 51% of all patients (with and without distant metastases).
(5) Two of the 37 patients who underwent mastectomy developed loco-regional recurrences; both had invasive foci at their first operation and remain disease free at 8 years.
(6) Among the 25 cases of recurrence, 1 was exclusively local and 6 were loco-regional (T and N), while 18 patients presented metastatic progression, either exclusively, or with local or lymph node failure.
(7) All patients where managed similarly: 3 to 4 courses of chemotherapy (CMF: n = 24; AVCF: n = 42), then loco regional irradiation therapy with cobalt 60, followed by maintenance chemotherapy, only if the first chemotherapy had proved effective (CMF: n = 13; AVCF: n = 27).
(8) Since there seems to be a direct relation between tumor size and the chance of loco-regional recurrence and since salvage operations for local failure are not uniformly successful, electrofulguration for cure must be reserved for the very rare patient with a very small early-stage rectal cancer.
(9) Although the recurrence rates of 37% and 49% by 50 Gy and 40 Gy were not statistically different, there was a strong trend of a better control rate of loco-regional carcinoma by higher radiation doses.
(10) From these results, it is reasonable to conclude that Kupffer cells alone are activated in a condition without a supply of monocytes from peripheral blood; proliferate and cluster in the hepatic sinusoids; transform into peroxidase-negative macrophages, epithelioid cells, and multinuclear giant cells; and participate in granuloma formation in loco together with T lymphocytes.
(11) Patients with T1 squamous cell carcinomas had, in fact, the best prognosis (26.5% recurred) among the subgroups obtained by stratification of T number and cell type together; loco-regional failure as exclusive modality of relapse had a 5-year rate of 19.7% and metastatic failure of 30.0%.
(12) In patients with Dukes' B tumours, an increased risk of loco-regional recurrence was associated with perineural invasion, tumour located less than 10 cm from the anal verge, patient aged above 70 years, and small tumour size.
(13) An effort was made to neutralize the virus in loco either by infiltration of the inoculation site with povidone-iodine or with monoclonal antibodies, or by cauterization and excision.
(14) To establish whether predictive clinical patterns of disease occur in localized Non-Hodgkin's lymphoma, survival and relapse patterns for 496 patients with stage I and II non-Hodgkin's lymphoma (NHL) treated with loco-regional irradiation (XRT) alone were examined.
(15) Radiotherapy alone may be appropriate treatment for extensive loco-regional tumours or in those that have already metastasized.
(16) Thus, adjuvant systemic treatment alone (chemotherapy or tamoxifen) did not prevent loco-regional recurrences in high-risk patients after mastectomy and axillary lymph node sampling.
(17) Three factors were found to be statistically significant: adjuvant hormonotherapy, loco-regional metastases, adjuvant adriamycin containing regimen (pejorative prognostic factor).
(18) Risk factors for loco-regional relapse (seven cases) included: large tumour bulk, treatment by XRT alone and use of 'limited' radiation fields.
(19) Following initial promising results in terms of loco-regional disease control in this group of high-risk patients, the protocol was extended to include 34 patients defined as having locally extensive disease.
(20) These changes may be related to the endothelial damage present scleroderma patients I the consequent "in loco" activation of blood coagulation may cause the microthrombosis that is very often observed in the earliest phases of the disease.
Locomotive
Definition:
(a.) Moving from place to place; changing place, or able to change place; as, a locomotive animal.
(a.) Used in producing motion; as, the locomotive organs of an animal.
(n.) A locomotive engine; a self-propelling wheel carriage, especially one which bears a steam boiler and one or more steam engines which communicate motion to the wheels and thus propel the carriage, -- used to convey goods or passengers, or to draw wagons, railroad cars, etc. See Illustration in Appendix.
Example Sentences:
(1) Platelet-activating factor (PAF-acether), an inflammatory mediator with a wide range of biological activities including neutrophil aggregation and chemotaxis, was studied for its effect on human eosinophil locomotion (chemotaxis and chemokinesis).
(2) The model can account for speed changes in locomotion with a relatively smooth change of system parameters.
(3) When the organisms are free-swimming this is seen as the reversed locomotion of Jennings' "avoiding reaction."
(4) In naïve mice, i.e., mice with intact stores of DA, both the selective D1 antagonist SCH23390 and the selective D2 antagonist spiperone blocked the locomoter stimulation produced by (+)-amphetamine.
(5) With respect to the mechanism of the delayed invasion, it was suggested that the IFN-gamma might inhibit the adhesion of the cells to extracellular matrices (ECM) and the subsequent locomotion.
(6) During normal locomotion, SA-m exhibited a single burst of EMG activity per step cycle, during the swing phase.
(7) a 45-mg pellet every 45 s) induces considerable locomotion, rearing and other motor activities in food-deprived rats.
(8) One hypothesis to account for intercellular invasion proposes that a necessary condition for a cell type to be invasive to a given host tissue is that it lack contact paralysis of locomotion during collision with cells of that host tissue.
(9) The failure of agents which inhibit motility to inhibit capping of the normal lymphocytes suggests that active locomotion is not a direct prerequisite for capping.
(10) The average speed of the cells, as well as the proportion of neutrophils showing locomotion, is increased.
(11) In the rotatory and transverse gallop (examples of the in-phase form of locomotion) the coupling is asymmetrical: on one side it is comparable to pacing (forelimb flexion precedes hindlimb extension), and on the other side to trotting (forelimb flexion follows extension).
(12) Wandering is movement changing over time and, thus, is a nonlinear ultradian rhythm, with locomoting and nonlocomoting phases.
(13) Locomotion and general activities were typically unchanged over days.
(14) While executing the latter movements no forward locomotion occurred at all; the cats solely executed lateral fore- and hindlimb movements opposite to the direction in which the cylinder rotated.
(15) In addition, this drug slightly reduced locomotion and more markedly rearing in a free exploration procedure.
(16) Animals injected with DZP, NPC 12626, CPP or buspirone spent at least 1.4 of the 4 post shock minutes locomoting.
(17) injection of bremazocine, an opiate kappa-receptor agonist, suppressed spontaneous locomotion but not CRF-induced locomotion.
(18) Without shocks, apomorphine-treated rats displayed stereotypy with locomotion and biting of various objects.
(19) Absence of a functioning velocity storage network in bottom-dwelling teleosts (as in Amphibia) may be related to the sporadic, slow locomotion of these species and the resulting small requirements for continuous gaze stabilization during self-motion at higher velocities.
(20) reversed the increase in locomotion and elevation of multiple squeak thresholds in the bilaterally kindled rats.