(a.) Moving from place to place; changing place, or able to change place; as, a locomotive animal.
(a.) Used in producing motion; as, the locomotive organs of an animal.
(n.) A locomotive engine; a self-propelling wheel carriage, especially one which bears a steam boiler and one or more steam engines which communicate motion to the wheels and thus propel the carriage, -- used to convey goods or passengers, or to draw wagons, railroad cars, etc. See Illustration in Appendix.
Example Sentences:
(1) Platelet-activating factor (PAF-acether), an inflammatory mediator with a wide range of biological activities including neutrophil aggregation and chemotaxis, was studied for its effect on human eosinophil locomotion (chemotaxis and chemokinesis).
(2) The model can account for speed changes in locomotion with a relatively smooth change of system parameters.
(3) When the organisms are free-swimming this is seen as the reversed locomotion of Jennings' "avoiding reaction."
(4) In naïve mice, i.e., mice with intact stores of DA, both the selective D1 antagonist SCH23390 and the selective D2 antagonist spiperone blocked the locomoter stimulation produced by (+)-amphetamine.
(5) With respect to the mechanism of the delayed invasion, it was suggested that the IFN-gamma might inhibit the adhesion of the cells to extracellular matrices (ECM) and the subsequent locomotion.
(6) During normal locomotion, SA-m exhibited a single burst of EMG activity per step cycle, during the swing phase.
(7) a 45-mg pellet every 45 s) induces considerable locomotion, rearing and other motor activities in food-deprived rats.
(8) One hypothesis to account for intercellular invasion proposes that a necessary condition for a cell type to be invasive to a given host tissue is that it lack contact paralysis of locomotion during collision with cells of that host tissue.
(9) The failure of agents which inhibit motility to inhibit capping of the normal lymphocytes suggests that active locomotion is not a direct prerequisite for capping.
(10) The average speed of the cells, as well as the proportion of neutrophils showing locomotion, is increased.
(11) In the rotatory and transverse gallop (examples of the in-phase form of locomotion) the coupling is asymmetrical: on one side it is comparable to pacing (forelimb flexion precedes hindlimb extension), and on the other side to trotting (forelimb flexion follows extension).
(12) Wandering is movement changing over time and, thus, is a nonlinear ultradian rhythm, with locomoting and nonlocomoting phases.
(13) Locomotion and general activities were typically unchanged over days.
(14) While executing the latter movements no forward locomotion occurred at all; the cats solely executed lateral fore- and hindlimb movements opposite to the direction in which the cylinder rotated.
(15) In addition, this drug slightly reduced locomotion and more markedly rearing in a free exploration procedure.
(16) Animals injected with DZP, NPC 12626, CPP or buspirone spent at least 1.4 of the 4 post shock minutes locomoting.
(17) injection of bremazocine, an opiate kappa-receptor agonist, suppressed spontaneous locomotion but not CRF-induced locomotion.
(18) Without shocks, apomorphine-treated rats displayed stereotypy with locomotion and biting of various objects.
(19) Absence of a functioning velocity storage network in bottom-dwelling teleosts (as in Amphibia) may be related to the sporadic, slow locomotion of these species and the resulting small requirements for continuous gaze stabilization during self-motion at higher velocities.
(20) reversed the increase in locomotion and elevation of multiple squeak thresholds in the bilaterally kindled rats.
Locomotor
Definition:
(a.) Of or pertaining to movement or locomotion.
Example Sentences:
(1) Spontaneous locomotor activity was lower in naloxone-infused rats on day 3 only.
(2) The GABA receptor agonist progabide reduced VCMs and locomotor activity.
(3) Components of locomotor activity were measured in an open field.
(4) The present results suggest that the locomotor-stimulatory and positive reinforcing effects of ethanol as well as its enhancing effect on dopaminergic activity may involve an enhancement of calcium mediated mechanisms.
(5) This, however will not result in normal lower leg bones, as can be concluded from the fact that spontaneous fractures have occurred partly even in the locomotor apparatus after the pseudarthroses had healed.
(6) As expected, chronic administration led to complete tolerance to caffeine's locomotor stimulant effect, while subchronic administration produced sensitization.
(7) A rich protein solution obtained from the seaweed was assayed for myorelaxant, anticonvulsant and analgesic activity and for its effects on spontaneous locomotor activity, amphetamine-induced hypermotility, exploratory behaviour, barbiturate-induced sleep, and body temperature.
(8) Some organization schemes concerning locomotor and scratching rhythmicity generators are considered, such as: two half-centres with reciprocal inhibitory connections and tonic excitatory influences on these half-centres: two half-centres with inhibitory-excitatory connections and tonic excitatory influences on one half-centre; ring structures consisting of more than two functional groups of neurons with excitatory and inhibitory connections between them.
(9) Results suggest that the locomotor activating effects of CRF may be due to an activation of CRF receptors in the ventral forebrain, a region rich in CRF cell bodies and projections.
(10) However, when mice pretreated with reserpine 24 h earlier were used, NPA was found to be 6.5 times more active in producing locomotor stimulation and 8.7 times more active in producing stereotypy than apomorphine.
(11) Different reactions of FR on thermostimulation of different areas of the crus are explained by the locomotor generation control of afferent information.
(12) Most falls occurred for reasons external to the patient, but internal reasons, both nonlocomotor and locomotor, increased after age 65 years.
(13) However, the blockade of locomotor stimulation in mice by AMPT could be reversed by their prior treatment with a low, behaviorally inactive dose of L-DOPA.
(14) There were striking age- and dose-dependent differences in both intensities and durations of morphine-induced locomotor activity.
(15) This suggests that the locomotor stimulation induced by amphetamine involves central norepinephrine, while dopamine neurons play an important role in the induced compulsive gnawing behavior.
(16) Comparisons of hominoid metacarpals and phalanges reveal differences, many of which are closely linked to locomotor hand postures.
(17) The present study examines the possibility that this modulation may originate from the spinal cord locomotor networks rather than from the brainstem.
(18) These results demonstrate that the therapeutic window of halothane anesthesia for protection of hippocampal injury precedes the phase of locomotor hyperactivity, and that the appearance of the latter predicts delayed neuronal death.
(19) After high doses of DALA, locomotor activity in the center and at the periphery of the box were decreased.
(20) It is postulated that these low doses of cocaine which depress locomotor activity do so via inhibition of serotonin uptake, resulting in potentiation of serotonergic activity.