(n.) The line traced by a point which varies its position according to some determinate law; the surface described by a point or line that moves according to a given law.
Example Sentences:
(1) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(4) The Notch locus in Drosophila encodes a transmembrane protein required for the determination of cell fate in ectodermal cells.
(5) The second protein could represent either an allozymic form of the enzyme or the product of a distinct locus.
(6) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
(7) The effects of clozapine on the spontaneous firing rate of noradrenergic (NE, locus coeruleus), dopaminergic (DA, zona compacta, ventral tegmental area) and non-dopaminergic (zona reticulata) neurons was studied in chloral hydrate anesthetized rats.
(8) Twenty-nine deletion breakpoints were mapped in 220 kb of the DXS164 locus relative to potential exons of the Duchenne and Becker muscular dystrophy gene.
(9) Mice homozygous for mutations at either locus exhibit several phenotypic abnormalities including a virtual absence of mast cells.
(10) These data suggest that increased TNF production may be responsible for endotoxin hypersensitivity in TCDD-treated mice and that the Ah locus mediates this response.
(11) (3) Two RFLP defined patterns of the DQA1 locus, DQA1.5 (DQA1*0501) and DQA1.8 (DQA1*0401, *0601) are strongly associated with the disease.
(12) Interspecific hybridization between sexual species carrying different b-alleles and producing different B subunits may be responsible for the heterozygosity at the lactate dehydrogenase b-locus in diploid parthenogenetic Cnemidophours.
(13) These findings are consistent with reports that implicate the PYK locus in yeast cell cycle control and suggest that it may be challenging to model relations between fitness and activity for multifunctional proteins.
(14) Evidence for a third locus, ENO3, is supplied by the electrophoretic pattern of muscle extracts.
(15) The data indicate that the locus for the alpha chain of the T-cell receptor is split by the chromosomal breakpoint between the V alpha and the C alpha gene segments, and that the V alpha segments are proximal to the C alpha segment within chromosome band 14q11.2.
(16) The new scale appears to be a more sensitive measure of locus of control than Rotter's scale.
(17) Incomplete penetrance of the simpler pattern suggests that this genetic locus interacts in a probabilistic manner with epigenetic mechanisms involved in morphogenesis of the cerebellum.
(18) Proposed models for the inheritance of locus-specific methylation phenotypes in somatic cells include those in which there is stable inheritance of a methylation pattern such that all cells contain a similarly methylated locus, as well as models in which the inheritance of methylation can be variable.
(19) Extensive LSR data were obtained as a by-product of specific-locus experiments.
(20) The deficits noted in the granule cells of the dentate gyrus in this study were more severe than those found in our previous studies on the effect of the low protein diet in these same rats on visual cortical pyramidal cells and on the 3 cell types in the nucleus raphe dorsalis and nucleus locus coeruleus.
Nidus
Definition:
(n.) A nest: a repository for the eggs of birds, insects, etc.; a breeding place; esp., the place or substance where parasites or the germs of a disease effect lodgment or are developed.
Example Sentences:
(1) The nidus was excised totally, then a gradual improvement of those symptoms followed.
(2) The roentgenographic appearance of most lesions consisted of a radiolucent central nidus encircled by sclerotic bone.
(3) It was suggested that the dorsum of the tongue may function as a nidus for periodontopathic micro-organisms.
(4) Osteoid osteomas were removed by CT-guided core drill excision of the nidus in 4 patients.
(5) The nidus was significantly reduced and total removal of the nidus was successfully done 28 days following the embolization.
(6) Angiograms obtained prior to treatment in 53 cases of deep-seated cerebral arteriovenous malformations (AVM's) were retrospectively analyzed with particular attention to the topography of the AVM nidus and the venous drainage.
(7) As kala-azar patients and dogs infected with visceral leishmaniasis are mostly in the area below 1,600 m sea level and the area above 2,000 m sea level is unpopulated, the natural infection of sandflies was thought, therefore, to come from wild animal hosts and the natural nidus of kala-azar there warrants further investigation.
(8) Slit-like cysts may result from old haemorrhage from the AVM nidus.
(9) MR angiograms were also helpful for further defining the nidus.
(10) Precipitation of calcium salts from bile is important in pigment gallstone formation and may serve as a nidus for cholesterol precipitation.
(11) Total extirpation of the nidus was successful in 32 cases, while no surgery was undertaken in 15.
(12) These ovoid bodies then appeared to serve as a nidus for further extensive basement membrane calcification.
(13) Because AP binds amyloid fibrils, codistribution of amyloid deposits and AP in amyloid elastosis strongly supports the theory that elastic fiber-associated AP may act as a nidus for amyloid deposition.
(14) An adhesion is considered as a nidus for segmental sclerosis; as the adhesion progresses, the related tuft regions turn into sclerosis.
(15) In pathological conditions, thrombogenic surfaces act as a nidus for platelet adherence and thrombus formation.
(16) Radiological investigation showed a typical feature for osteoblastoma of iliac bone, with two niduses.
(17) MR imaging was also inferior to angiography in determining the nidus and the exact nature of collateral vascular structures in arteriovenous malformations.
(18) The papilla of Vater, diminutive as it may be, forms the nidus for a variety of clinical disorders.
(19) If septic shock ensues, extirpation of the nidus of infection becomes a primary consideration.
(20) The relatively large nidus of the AVM was located mainly in the anterior portion of the corpus callosum, and there was a smaller nidus in the splenium.