(n.) The line traced by a point which varies its position according to some determinate law; the surface described by a point or line that moves according to a given law.
Example Sentences:
(1) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(4) The Notch locus in Drosophila encodes a transmembrane protein required for the determination of cell fate in ectodermal cells.
(5) The second protein could represent either an allozymic form of the enzyme or the product of a distinct locus.
(6) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
(7) The effects of clozapine on the spontaneous firing rate of noradrenergic (NE, locus coeruleus), dopaminergic (DA, zona compacta, ventral tegmental area) and non-dopaminergic (zona reticulata) neurons was studied in chloral hydrate anesthetized rats.
(8) Twenty-nine deletion breakpoints were mapped in 220 kb of the DXS164 locus relative to potential exons of the Duchenne and Becker muscular dystrophy gene.
(9) Mice homozygous for mutations at either locus exhibit several phenotypic abnormalities including a virtual absence of mast cells.
(10) These data suggest that increased TNF production may be responsible for endotoxin hypersensitivity in TCDD-treated mice and that the Ah locus mediates this response.
(11) (3) Two RFLP defined patterns of the DQA1 locus, DQA1.5 (DQA1*0501) and DQA1.8 (DQA1*0401, *0601) are strongly associated with the disease.
(12) Interspecific hybridization between sexual species carrying different b-alleles and producing different B subunits may be responsible for the heterozygosity at the lactate dehydrogenase b-locus in diploid parthenogenetic Cnemidophours.
(13) These findings are consistent with reports that implicate the PYK locus in yeast cell cycle control and suggest that it may be challenging to model relations between fitness and activity for multifunctional proteins.
(14) Evidence for a third locus, ENO3, is supplied by the electrophoretic pattern of muscle extracts.
(15) The data indicate that the locus for the alpha chain of the T-cell receptor is split by the chromosomal breakpoint between the V alpha and the C alpha gene segments, and that the V alpha segments are proximal to the C alpha segment within chromosome band 14q11.2.
(16) The new scale appears to be a more sensitive measure of locus of control than Rotter's scale.
(17) Incomplete penetrance of the simpler pattern suggests that this genetic locus interacts in a probabilistic manner with epigenetic mechanisms involved in morphogenesis of the cerebellum.
(18) Proposed models for the inheritance of locus-specific methylation phenotypes in somatic cells include those in which there is stable inheritance of a methylation pattern such that all cells contain a similarly methylated locus, as well as models in which the inheritance of methylation can be variable.
(19) Extensive LSR data were obtained as a by-product of specific-locus experiments.
(20) The deficits noted in the granule cells of the dentate gyrus in this study were more severe than those found in our previous studies on the effect of the low protein diet in these same rats on visual cortical pyramidal cells and on the 3 cell types in the nucleus raphe dorsalis and nucleus locus coeruleus.
Variant
Definition:
(a.) Varying in from, character, or the like; variable; different; diverse.
(a.) Changeable; changing; fickle.
(n.) Something which differs in form from another thing, though really the same; as, a variant from a type in natural history; a variant of a story or a word.
Example Sentences:
(1) This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign course.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(5) In this study, the role of psychological make-up was assessed as a risk factor in the etiology of vasospasm in variant angina (VA) using the Cornell Medical Index (CMI).
(6) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
(7) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(8) A variant t-PA (G K1 K2 P), which contained only one of the two fibrin binding sites, i.e.
(9) In the DAUDI cell system, the acquired capability of tumor cell variants to grow in the presence of a relatively high concentration of vinblastine (VBL) is associated with a marked increase to NK and LAK susceptibility.
(10) An infant with a Sturge-Weber variant syndrome developed progressive megalencephaly and eventual hydrocephalus, which required shunting.
(11) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(12) Furthermore, they seem to suggest that most cases of cycloid psychosis are not variants of either schizophrenia or major affective disorders.
(13) Structurally altered polymorphic variants with reduced activity, such as tetrameric interface mutant Ile-58 to Thr, may produce not only an early selective advantage, through enhanced cytotoxicity of tumor necrosis factor for virus-infected cells, but also detrimental effects from increased mitochondrial oxidative damage, contributing to degenerative conditions, including diabetes, aging, and Parkinson's and Alzheimer's diseases.
(14) A variant of the FitzHugh-Nagumo model is proposed in order to fully make use of the computational properties of intraneuronal dynamics.
(15) All four human MBP variants were identical except for the insertion of deletion of two peptide fragments corresponding to those encoded by exons 2 and 5 of the MBP gene.
(16) Proliferation of untransformed FDC-PI cells and the emergence of variants with improved adaptation to in vivo conditions appear to be important and possibly necessary steps in the pathogenesis of the disease.
(17) The results are discussed with respect to Q phase variants and receptor binding properties.
(18) In small cell line NCI-H69 the growth inhibitory effect of VRP alone is greater in the resistant variant than in the parent line.
(19) A deficient G-6PD variant was discovered in 4 males of one family from northwestern Germany.
(20) Methods of analysis for some deterministic and stochastic variants of the integrate-to-threshold neural coding scheme are presented.